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A traditional Chinese medicine combination extract with freckle-removing and whitening effects and its application

A technology for removing freckles, whitening, and extracts, which is applied in the field of fine chemical daily necessities, can solve the problems of beauty and whitening that have not been reported, and achieve the effect of overcoming unstable effects, stable effects, and clear effects

Active Publication Date: 2019-06-04
QINGDAO UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the research on Lycium barbarum is mostly focused on the extraction and biological activity of the pigments and polysaccharides contained in the fruit, but there is no report on the beauty and whitening of the leaf extract.

Method used

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  • A traditional Chinese medicine combination extract with freckle-removing and whitening effects and its application
  • A traditional Chinese medicine combination extract with freckle-removing and whitening effects and its application
  • A traditional Chinese medicine combination extract with freckle-removing and whitening effects and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] 40 parts of black wolfberry leaves, 30 parts of Panax notoginseng leaves, 10 parts of Nepeta nepeta, 10 parts of crabapple leaves, 10 parts of Duyiwei

[0028] Take dried black fruit wolfberry leaves, Panax notoginseng leaves, Nepeta japonica, Begonia variegata leaves, and unique medicinal materials, grind them, pass through a 20-mesh sieve, add 8 times the amount (V / m) of 70% ethanol according to the volume-to-mass ratio, and reflux Extract 2 times, extract 2 hours each time, filter, combine the filtrates, recover ethanol under reduced pressure at 65°C until there is no alcohol smell, then purify on AB-8 macroporous resin column, collect 60% ethanol eluted fraction, Recover ethanol under reduced pressure at 60°C to obtain extract, dry in vacuum at 70°C, and pulverize, which is the traditional Chinese medicine combination extract with freckle-removing and whitening effects of the present invention.

Embodiment 2

[0030] 30 parts of black wolfberry leaves, 30 parts of Panax notoginseng leaves, 10 parts of Nepeta japonica, 10 parts of crabapple leaves, 20 parts of Duyiwei

[0031]Take dried black wolfberry leaves, Panax notoginseng leaves, Nepeta japonica, Begonia variegata leaves, and unique medicinal materials, grind them, pass through a 20-mesh sieve, add 5 times the amount (V / m) of 60% ethanol according to the volume-to-mass ratio, and reflux Extract 3 times, extract 1 hour each time, filter, combine the filtrates, recover ethanol under reduced pressure at 55°C until there is no alcohol smell, then purify on a D101 macroporous resin column, collect 50% ethanol eluted fraction, and store at 60°C The ethanol is recovered under reduced pressure under the conditions to obtain the extract, which is vacuum-dried at 60° C. and pulverized, which is the Chinese medicine combination extract with the effect of removing freckles and whitening of the present invention.

Embodiment 3

[0033] 20 parts of black wolfberry leaves, 40 parts of Panax notoginseng leaves, 20 parts of Nepeta nepeta, 10 parts of crabapple leaves, 10 parts of Duyiwei

[0034] Take dried black fruit wolfberry leaves, Panax notoginseng leaves, Nepeta japonica, Begonia variegata leaves, and unique medicinal materials, grind them, pass through a 20-mesh sieve, add 6 times the amount (V / m) of 80% ethanol according to the volume-to-mass ratio, and reflux Extract once, extract 3 hours each time, filter, combine filtrates, recover ethanol under reduced pressure at 75°C until there is no alcohol smell, then purify on AB-8 macroporous resin column, collect 70% ethanol eluted fraction, Recover ethanol under reduced pressure at 60°C to obtain extract, vacuum-dry at 55°C, and pulverize, which is the traditional Chinese medicine combination extract with freckle-removing and whitening effects of the present invention.

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Abstract

The invention discloses a traditional Chinese medicine combination extract with effects of removing beverage and whitening skin. The traditional Chinese medicine combination extract is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-40 parts of black lycium barbarum leaves, 10-40 parts of panax notoginseng leaves, 10-30 parts of nepeta hemsleyana,10-30 parts of malus toringoides leaves and 10-30 parts of lamiophlomis rotate. The traditional Chinese medicine combination extract disclosed by the invention has the characteristics of beverage removal and skin whitening, nature and safety and synergistic interaction.

Description

technical field [0001] The invention belongs to the technical field of fine chemical daily necessities, and specifically relates to a traditional Chinese medicine combination extract with freckle-removing and whitening effects and its application. Background technique [0002] The skin is a barrier of the human body, which can reflect the health status of the human body to a certain extent. With the changes of the natural environment and personal health status and the increasing external pressure, the vitality of the body's own antioxidant system decreases, oxygen free radicals in the body increase, and tyrosinase increases, which will cause melanin deposition and pigmentation. , leading to dull skin. [0003] There are many reasons for the production of melanin, such as ultraviolet exhaust gas, active oxygen and other environmental problems, and some genetic factors. The reasons for its production are quite complicated. The general research results show that the process of...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61Q19/02
CPCA61K8/97A61Q19/02
Inventor 黄山常柄权孟宁李斌
Owner QINGDAO UNIV OF SCI & TECH
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