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A gum base composition for protecting oral flora balance and preparation method thereof

A technology of flora balance and composition, which is applied in the field of gum-based compositions to protect the balance of oral flora, can solve the problems of inability to achieve comprehensive and comprehensive prevention and treatment of tooth sensitivity, and achieve strong market application value, long-term antibacterial properties, The effect of repairing dentin defects

Active Publication Date: 2020-03-27
北京刷新活力健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This document does not involve bioactive mineral powders or other bactericidal substances with a particle size greater than 90 μm. Since bioactive powders with larger particles can more effectively repair soft tissue damage in the oral cavity, the products provided in this document cannot achieve Comprehensive and comprehensive prevention and treatment of a series of oral problems such as tooth sensitivity, gingivitis, and oral ulcers

Method used

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  • A gum base composition for protecting oral flora balance and preparation method thereof
  • A gum base composition for protecting oral flora balance and preparation method thereof
  • A gum base composition for protecting oral flora balance and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0034] This embodiment provides a gum base composition for protecting the balance of oral flora, which consists of: 30 g of butyl rubber gum base, 9 g of bioactive mineral powder, 0.1 g of polylysine, 1 g of phosphate, and flavoring agent 20g, xylitol sweetener 15g, sorbitol flavoring agent 25g;

[0035] The composition of the bioactive mineral powder is: SiO 2 45%, CaO 25%, Na 2 O 24.5%, P 2 o 5 5.5%; the particle size of the biologically active mineral powder is 0.1-50 μm, and the mineral powder with 0.01 μm≤particle size≤20 μm accounts for 80-95% of the total amount.

Embodiment 2

[0037] This embodiment provides a gum base composition for protecting the balance of oral flora, which consists of: 29 g of butyl rubber gum base, 12 g of bioactive mineral powder, 0.02 g of polylysine, 1 g of phosphate, and flavoring agent 20g, xylitol sweetener 15g, sorbitol flavoring agent 23g;

[0038] The composition and particle size of the bioactive mineral powder are the same as in Example 1.

Embodiment 3

[0040] This embodiment provides a gum base composition for protecting the balance of oral flora, which consists of: 32 g of butyl rubber gum base, 5 g of bioactive mineral powder, 0.05 g of polylysine, 1 g of phosphate, and flavoring agent 20g, xylitol sweetener 17g, sorbitol flavoring agent 25g;

[0041] The composition and particle size of the bioactive mineral powder are the same as in Example 1.

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Abstract

The invention relates to a gum base composition for protecting the balance of oral flora. The gum-based composition is prepared from a gum base, bioactivity mineral powder and polylysine, wherein a weight proportion of the bioactivity mineral powder and the polylysine is (2 to 25) : (0.0003 to 10). According to the gum base composition disclosed by the invention, the bioactivity mineral powder and the polylysine in the gum base composition are capable of inhibiting and killing various pathogenic bacteria in an oral cavity, preventing and treating oral problems of oral infection, oral ulcer, chronic gingisitis and the like, and have long-acting bacteria resistance; meanwhile, the bioactivity mineral powder and the polylysine have a certain selective protection function on beneficial bacteria in the oral cavity, the balance of flora in the oral cavity can be effectively regulated, and normal sanitation and health of the oral cavity can be maintained. Through remineralization of the bioactivity mineral powder on teeth, the gum base composition is capable of effectively repairing dentin defects; the gum base composition provided by the invention is convenient to use, wide in receiver groups and very strong in market application value.

Description

technical field [0001] The invention relates to the field of prevention and treatment of oral diseases, in particular to a gum base composition for protecting the balance of oral flora. Background technique [0002] Bioactive mineral powder is an important inorganic bioactive material. It has a special inorganic amorphous structure and has excellent properties such as improving cell activity and promoting biomineralization. It is a class of more crystalline bioactive materials than other crystalline bioactive materials. Excellent tissue repair material. Bioactive mineral powder was first discovered by Professor Hench in 1969, and its composition includes SiO 2 、Na 2 O, CaO, P 2 o 5 Wait. The degradation products of bioactive mineral powder can promote the generation of growth factors, promote the reproduction of cells, enhance the gene expression of osteoblasts and the growth of bone tissue. Artificial biomaterials connected with soft tissues are considered to be good ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/42A61P1/02A61P31/02A61P31/04A61K31/785A61K33/08A61K33/00A61K33/16
CPCA61K31/785A61K33/00A61K33/08A61K33/16A61K33/42A61K2300/00
Inventor 常丽李次会
Owner 北京刷新活力健康科技有限公司
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