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A kind of process of extracting hematine from Huangteng fruit

A technology of extracting drosophila from yellow vine fruit and draconicin, which can solve the problems such as failure to meet the requirements of qualitative and quantitative reference substances and low purity of draconicin.

Active Publication Date: 2019-09-10
南宁成泰生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention provides a process for extracting Drassantrin from Huangteng fruit to solve the problem that the purity of the extracted and purified Dsheratin from Huangteng fruit is low and cannot meet the requirements of qualitative and quantitative reference substances

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A process for extracting hematogenin from Huangteng fruit, comprising the following steps:

[0037] S1: Pulverizing the fruit of the yellow vine fruit and passing it through a 50-mesh sieve to obtain the fruit of the yellow vine fruit;

[0038] S2: Add 7 times of its weight 72% ethanol to the yellow vine fruit powder prepared in step S1, and extract twice under ultrasonic reflux under water bath conditions, the frequency of each ultrasonic wave is 620W, the temperature is 46°C, and the time is 14min. After the extraction is complete, combine the extracts, adjust the pH value of the extracts to 4.2, control the temperature at 46°C, decolorize and remove impurities by activated carbon for 1.2 hours, and obtain a decolorized solution after filtration;

[0039] S3: Concentrate and dry the primary decolorization solution obtained in step S2 to obtain an extract extract, which is dissolved in water at 52°C with 5.6 times the volume of the extract extract, and extracted twice ...

Embodiment 2

[0044] A process for extracting hematogenin from Huangteng fruit, comprising the following steps:

[0045] S1: Pulverizing the fruit of the yellow vine fruit and passing it through a 30-mesh sieve to obtain the fruit of the yellow vine fruit;

[0046] S2: Add 6 times the weight of 68% ethanol to the yellow vine fruit powder prepared in step S1, and extract twice by ultrasonic reflux under water bath conditions. The frequency of each ultrasonic wave is 560W, the temperature is 42°C, and the time is 15min. After the extraction is complete, combine the extracts, adjust the pH value of the extracts to 4, control the temperature at 42°C, decolorize and remove impurities by activated carbon for 1.4 hours, and obtain a decolorized solution after filtration;

[0047] S3: Concentrate and dry the primary decolorization solution obtained in step S2 to obtain an extract extract, which is dissolved in water at 50° C. with 5 times the volume of the extract extract, extracted twice with anhy...

Embodiment 3

[0052] A process for extracting hematogenin from Huangteng fruit, comprising the following steps:

[0053] S1: Pulverize the fruit of the yellow vine and pass it through a 60-mesh sieve to obtain the powder of the fruit of the yellow vine;

[0054] S2: Add 8 times its weight of 78% ethanol to the yellow vine fruit powder prepared in step S1, and extract it under ultrasonic reflux for 3 times under water bath conditions, the frequency of each ultrasonic wave is 720W, the temperature is 50°C, and the time is 12min. After the extraction is complete, combine the extracts, adjust the pH value of the extracts to 4.3, control the temperature at 50°C, decolorize and remove impurities by activated carbon for 0.8h, and obtain a decolorized solution after filtration;

[0055] S3: Concentrate and dry the primary decolorization solution obtained in step S2 to obtain an extract extract, which is dissolved in water at 55° C. with 6.2 times the volume of the extract extract, extracted 3 times...

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PUM

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Abstract

The invention discloses a process for extracting dracorhodin from herba fibraureae recisae fruits and belongs to the technical field of extraction of effective components of the herba fibraureae recisae fruits. The dracorhodin is prepared through the following steps of crushing, carrying out primary de-coloring, coarsely crystallizing, carrying out secondary de-coloring, carrying out macro-porous adsorption resin separation and purification, concentrating and crystallizing, drying and the like. According to the method disclosed by the invention, the extraction yield of the dracorhodin is 40.94 percent or more and the purity of the dracorhodin is 98.35 percent or more; the purity reaches qualitative and quantitative reference substance requirements.

Description

[0001] 【Technical field】 [0002] The invention belongs to the technical field of extracting active ingredients from the fruit of the yellow vine, and in particular relates to a process for extracting hematogenin from the fruit of the yellow vine. [0003] 【Background technique】 [0004] Dracaena, also known as dracaena deep red pigment, is one of the important active ingredients in Huangteng fruit. According to literature reports, heserodin has antibacterial, antiviral and other activities. In recent years, research on the potential anticancer activity of heserotonin has attracted wide attention. There are very few reports in the published literature on the extraction and purification of prostaglandin from Huangteng fruit, and the purity of the obtained prostaglandin is low, which cannot meet the requirements for qualitative and quantitative reference substances. [0005] 【Content of invention】 [0006] The invention provides a process for extracting hessantrin from the fru...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07D311/60
Inventor 梁可文黄能谢冬养
Owner 南宁成泰生物科技有限公司