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Maca extract with sexual dysfunction improving function and preparation method and application thereof

A technology for maca extract and improving sexual function, applied in the field of medicine, can solve the problems of complex process flow, no quality control method for maca extract, no safety research, etc.

Inactive Publication Date: 2017-07-25
YUNNAN INST OF MATERIA MEDICA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Publication number is the preparation method of the maca extract that the Chinese patent application of CN104513173A provides, first obtains the maca crude extract with solvent extraction, then organic solvent extraction obtains an extract, continues to purify as purification raw material and obtains macamide content relatively High maca extract, the method needs to extract, extract, and pass through the chromatographic column, and the process is complicated; in addition, the patent does not provide the quality control method of maca extract, nor has its safety research been carried out

Method used

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  • Maca extract with sexual dysfunction improving function and preparation method and application thereof
  • Maca extract with sexual dysfunction improving function and preparation method and application thereof
  • Maca extract with sexual dysfunction improving function and preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0032] Take 100kg of dried Maca roots, pulverize them, sieve (40 meshes), and extract the medicinal powder with petroleum ether (60-90°C) under reflux at 80°C for three times, adding petroleum ether (60-90°C) each time as the raw material 5 times, 4 times, and 4 times the weight, reflux for 3 hours for the first time, reflux for 2 hours each for the second and third times, filter, combine the filtrates, concentrate under reduced pressure to recover the solvent, and dry to obtain the maca extract. The yield is 1.34kg. The yield was 1.34%. The extract mainly contains macamide active ingredients: N-benzyl linoleamide, N-benzyl linoleamide and N-benzyl hexadecanamide. The total macamide content in this extract is up to 70% by HPLC. %.

Embodiment 2

[0034] Take 100kg of dried maca root, pulverize, sieve (20 mesh), add 15 times the weight of raw material to ethyl acetate, extract by percolation at room temperature (20-30°C), filter, combine the filtrates, concentrate under reduced pressure to recover the solvent, Dried to obtain maca extract; the extract mainly contains macamide active ingredients: N-benzyl linoleamide, N-benzyl linoleamide and N-benzyl hexadecanamide, detected by HPLC in this extract The total macamide content reaches 99%.

Embodiment 3

[0036] Take 100kg of dried maca roots, pulverize them, sieve (20 meshes), add acetone 5 times the weight of the raw materials to the medicinal powder, extract ultrasonically at 40°C for 1 hour, filter, combine the filtrates, concentrate under reduced pressure to recover the solvent, and dry to obtain the maca extract. The extract mainly contains macamide active ingredients: N-benzyl linoleamide, N-benzyl linoleamide and N-benzyl hexadecanamide, and the total macamide content in the extract is detected by HPLC up to 30%.

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Abstract

The invention relates to a maca extract with sexual dysfunction improving function and a preparation method and application thereof. The maca extract is an effective part which is extracted from maca, and mainly consists of maca amide active ingredients, such as N-benzyl linenamide, N-benzyl linoleamide, and N-benzyl hexadecanamide. In the maca extract of effective part, the content of maca amide is 30% to 100%. The invention also provides a preparation method of the maca extract, an active ingredient content measuring method and application. The maca extract has the advantages that the function of improving sexual dysfunction, improving fertility and resisting fatigue is good, and the effect is better than the effect of the maca raw material. The preparation method of the maca extract has the advantages that the preparation method is normal and standard, the technology is simple, and the industrialized production is easy; the content of effective component in maca extract is higher, and the medicine effect is clear.

Description

technical field [0001] The invention relates to a maca extract capable of improving sexual dysfunction, in particular to a maca extract with clear active ingredients extracted from maca, and its preparation method and application belong to the technical field of medicine. Background technique [0002] Maca (Lepidium meyenii Walp.) is an annual herb of the genus Lepidium in the family Cruciferae. Native to the Andes Mountains in South America at an altitude of 3500-4500m, it has the reputation of "Peruvian National Treasure" or "Peruvian Ginseng". In the past 10 years, it has gradually become one of the hot spots in the development of medicinal and edible plants in the world, and the scientific research and application of it in various countries are also deepening. The reason why maca stands out from many medicinal herbs in South America is that in addition to its mild nourishing effect, its claim to enhance sexual function is also a very important factor. The efficacy and ...

Claims

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Application Information

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IPC IPC(8): A61K36/31A61P15/08A61P39/00G01N30/02A61K125/00
Inventor 崔涛彭玲芳吴德松陆礼和王宁孙敏
Owner YUNNAN INST OF MATERIA MEDICA
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