A kind of isoleucine extraction process

Abstract

The invention relates to a corn deep processing method, which is an isoleucine extraction process, which comprises: filtering a fermentation liquid through a ceramic membrane to obtain a filtrate, removing impurities through a cation column, carrying out elution, collecting to obtain an isoleucine high flow liquid, removing impurities through an anion column, carrying out ultra-filtration to remove most of pigments, polysaccharides and large molecular weight soluble proteins to obtain an ultra-filtration filtrate, carrying out decolorization with active carbon, making the obtained material enter an evaporator through a decarburization machine, carrying out concentration crystallization to obtain an isoleucine crude product, making the wet finished product into an elutriation tank, adding purified water, mixing and stirring to obtain an elutriation liquid, beating into a cooling clean tank, cooling, separating, and drying the wet finished product. According to the present invention, the anion exchange column is additionally arranged, the grade of the product is improved to USP31 from USP24, the single elutriation is used to replace the secondary decolorization so as to substantially reduce the material loss, the energy consumption and the cost, and the yield of isoleucine is increased to more than 65% from 60%.

Description

technical field [0001] The invention relates to a corn deep processing method, namely an isoleucine extraction process. Background technique [0002] Isoleucine, also known as "isoleucine", is systematically named "α-amino-β-methylpentanoic acid". It is one of the essential amino acids for human body, chemical formula: CH3CH2CH(CH3)CH(NH2)COOH. Molecular weight: 131.17. L-isoleucine is an essential amino acid for the human body and one of the three branched-chain amino acids. Because of its special structure and function, it occupies a particularly important position in the metabolism of human life. L-Isoleucine is mainly used to prepare compound amino acid preparations, especially for high branched chain amino acid infusion (such as 3H infusion, etc.) and oral liquid (ganan dry syrup, etc.). At present, the isoleucine extraction process uses a cation exchange column to remove impurities and impurities, which can remove NH 4 + , Ca 2+ , Mg 2+ and other impurity ions a...

AI Technical Summary

Problems solved by technology

However, during the process of secondary crystallization and secondary separation to obtain the finished isoleucine product, a large amount of isoleucine mother liquor is produced, and the mother liquor goes to the separation column again, which increases the loss of mother liquor and the extraction and refining yield of isoleucine. Not high, only up to 60%, low yield, serious waste

Due to the adoption of the secondary crystallization process, the process route is longer, the energy consumption in the process of extracting isoleucine is relatively large, and the cost of the final product is relatively high.

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