Skin care/treatment composition with itch-relieving effect

A kind of treatment composition, skin care technology

Active Publication Date: 2020-08-25
成都华西珐玛生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In practice, it has been found that antihistamine preparations can relieve some skin itching mediated by histamine, but fail to produce effective relief for most skin itching; Temporarily relieve itching within a short period of time, but it cannot effectively reduce the possible skin inflammation and the cause of itching, and it cannot be used for a long time to avoid even very serious side effects

Method used

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  • Skin care/treatment composition with itch-relieving effect
  • Skin care/treatment composition with itch-relieving effect
  • Skin care/treatment composition with itch-relieving effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Embodiment 1: antipruritic repair cream (pharmaceutical preparation)

[0052] composition:

[0053] Composition gram Osmanthus Absolute Extract 0.02 Glycerin (Xiamen Xingsha Pharmaceutical Co., Ltd., batch number: 140901) 7.0 Stearic acid (Tianjin Dingshengxin Chemical Co., Ltd., production date: March 10, 2016) 8.0 Lanolin (Tianjin Zhiyuan Chemical Reagent Co., Ltd., production date: April 10, 2016) 2.0 Emulsifier (polysorbate-80, Chengdu Kelong Chemical Reagent Factory, batch number: 151201) 1.5 Preservatives (Genma BP, Shanghai Tongding Industrial Co., Ltd., batch number: 20160301) 0.1 Deionized water add up to 100

[0054] Preparation method: According to the conventional cosmetic preparation method, mix the sweet-scented osmanthus absolute extract, stearic acid, lanolin and polysorbate-80 in the above composition, heat and melt in a water bath at 70-80°C to form a liquid (oil phase). In addition, add glycer...

Embodiment 2

[0055] Embodiment 2: antipruritic repair emulsion (cosmetic preparation)

[0056] composition:

[0057] Composition gram Osmanthus Absolute Extract 0.04 Glycerin (same as Example 1) 6.0 Stearic acid (same as Example 1) 2.0 1,3-Butanediol (OXEA, USA, Shanghai Tongding Industrial Co., Ltd., batch number: 20160115) 1.0 Xylitol (Shandong Futian Pharmaceutical Co., Ltd., batch number: 116032307) 0.5 Emulsifier (with embodiment 1) 1.5 Antiseptic (same as embodiment 1) 0.1 Deionized water 89

[0058] Preparation method: According to the conventional cosmetic preparation method, mix the sweet-scented osmanthus absolute extract, stearic acid, xylitol and emulsifier in the above composition, heat and melt in a 70-80°C water bath to become liquid, keep the temperature at 70-80°C, and Under stirring, add 20 grams of deionized water, stir until emulsification is complete, and let cool. Add glycerin, 1,3-butanediol and preserv...

Embodiment 3

[0059] Embodiment 3: antipruritic repair milk (cosmetic preparation) composition:

[0060] Composition gram Osmanthus Absolute Extract 0.06 Glycerin (same as Example 1) 5.0 Sodium polyacrylate (Henan Siyuan Biotechnology Co., Ltd., batch number: 20151206) 0.3 1,3-Butanediol (OXEA, USA, Shanghai Tongding Industrial Co., Ltd., batch number: 20160115) 2.5 Vitamin B 5 (Guangzhou Guanghui Biotechnology Co., Ltd., batch number: 20160322)

[0061] Preparation method: dissolve 0.30 g of sodium polyacrylate into 70 ml of water, stir, and fully swell. Slowly add glycerin, 1,3-butanediol, EDTA-Na 2 and preservative, stirring constantly to obtain an aqueous phase liquid; another 10ml of deionized water was taken, polysorbate-80 emulsifier and sweet-scented osmanthus absolute extract were added, and stirred to make it into an emulsion. Add the emulsion into the water phase liquid, stir evenly, add deionized water to 100 grams, and sterilize at hig...

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Abstract

A skin care / treatment composition with the effect of relieving itching, the active ingredient is the extract in the form of osmanthus absolute, and the weight composition includes: 0.01%~0.2% of the extract in the form of osmanthus absolute, and the balance is acceptable in external preparations for skin Excipient ingredients. Wherein, the gas chromatography-mass spectrum of linalool derivatives, β-ionone derivatives, γ-decalactone derivatives, α-linolenic acid and linolenic acid esters as landmark components in the osmanthus absolute form extract The sum of the areas of the chromatographic ion peaks should be at least 15% of the total peak areas of the osmanthus absolute form extract liquid chromatography. Experiments have shown that the medicament and / or cosmetic preparations made from the skin care / treatment composition of the present invention can significantly relieve itching for various causes of skin itching and skin diseases accompanied by skin itching, and can help For the local maintenance and treatment of its diseased skin.

Description

technical field [0001] The invention relates to a skin maintenance / treatment composition capable of alleviating pruritus, which can be used as an external medicine or cosmetic having maintenance / treatment effects on skin with pruritus symptoms or diseases. Background technique [0002] Pruritus is an unpleasant sensation produced by human skin that causes the desire to scratch, and is a subjective feeling of humans or animals. Itching is not only a common symptom of many localized skin diseases, but may also be an external symptom of diseases in other parts of the body or organs / tissues on the skin. The specific mechanism is still unclear. [0003] According to whether the skin at the itching site shows abnormal conditions, skin itching can be divided into two types: skin itching with skin lesions and skin itching without skin lesions. [0004] The first type is skin itching with skin lesions, most of which are accompanied by skin diseases, such as skin itching caused by va...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/63A61K31/702A61K31/715A61K8/9789A61K8/60A61K8/73A61P17/04A61Q19/00
CPCA61K8/60A61K8/73A61K8/97A61K31/702A61K31/715A61K36/63A61Q19/00
Inventor 黄静王建忠刘显波
Owner 成都华西珐玛生物科技有限公司
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