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Micro-fluidic chip for realizing liquid droplet upward and downward separation, original droplet upward floating and injected substance sinking

A microfluidic chip and droplet technology, applied in fluid controllers, laboratory appliances, laboratory containers, etc., can solve problems such as activity, efficacy, performance, state changes, affecting applications, and adverse effects

Active Publication Date: 2017-10-10
李木
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006]However, the above method uses a strong electric field, which has a bad influence on the droplet and the samples inside the droplet, and even causes the samples screened by this method to Irreversible changes have taken place in the activity, efficacy, performance, and state of the product, which affects subsequent applications

Method used

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  • Micro-fluidic chip for realizing liquid droplet upward and downward separation, original droplet upward floating and injected substance sinking
  • Micro-fluidic chip for realizing liquid droplet upward and downward separation, original droplet upward floating and injected substance sinking
  • Micro-fluidic chip for realizing liquid droplet upward and downward separation, original droplet upward floating and injected substance sinking

Examples

Experimental program
Comparison scheme
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Embodiment 1

[0087] "Up and down sorting, injecting and sinking" droplet sorting: light droplets become heavier after being injected into the material, and the droplets are sorted along the upper and lower branches.

[0088] figure 1 It is a schematic diagram of this embodiment, and the number 1 is the liquid inlet interface; the number 2 is one liquid outlet interface; the number 3 is another liquid outlet interface; the number 4 is the substance injected into the droplet; the number 5 is the liquid filling port; The number 6 is the detection area; the number 7 is the liquid that has just entered the channel through the liquid inlet port; the number 8 is the liquid drop that has been added through the liquid filling port; A channel fork structure that implements sorting.

[0089] In this embodiment, the density of the liquid droplets of the present invention is lower than that of the surrounding liquid, and the density is higher than that of the surrounding liquid after selective injecti...

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Abstract

Provided is a micro-fluidic chip for realizing liquid droplet upward and downward separation, original droplet upward floating and injected substance sinking. The invention relates to the micro-fluidic chip and a control method of the micro-fluidic chip, especially to the micro-fluidic chip which can achieve liquid droplet separation through changing the density of liquid droplets and the control method of the micro-fluidic chip. The channel of the micro-fluidic chip is provided with upward and downward branch channels, the liquid droplets with an injected substance sink because the density of the liquid droplets with the injected substance is bigger than that of liquid around the liquid droplets with the injected substance, and the liquid droplets free of the injected substance float upward naturally because the density of the liquid droplets free of the injected substance is smaller than that of liquid around the liquid droplets free of the injected substance, so that separation of the two kinds of liquid droplets is achieved.

Description

technical field [0001] The invention relates to a microfluidic chip and a corresponding microfluidic method. Background technique [0002] In today's world economy, the process of drug research and development, medical testing, food development, biocatalysis, and chemical experiments in the fields of biotechnology, life technology, and chemical technology is complex and lengthy, involving many disciplines. Most of the experimental occasions still use traditional methods, including the use of liquid extractors, liquid extraction guns, kits and other tools, and are mostly carried out manually or semi-manually. The degree of automation is not high, the efficiency is low, and the amount of samples and raw materials used in the whole process On the high side, the waste is serious, making the cost of related materials, manpower, and management high. With the advancement of science and technology and the development of the times, many complex detections and experiments can be real...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/5027B01L2200/10B01L2200/027B01L2300/0864B01L2400/0469B01L2400/0457
Inventor 李木
Owner 李木
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