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Drug compound for treating fatty liver, preparation method and application thereof

A composition, fatty liver technology, applied in the direction of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., can solve the problems of lack of specific drugs, poor treatment effect, etc. Sexual diseases, anti-aging effect

Inactive Publication Date: 2017-10-24
YANGTZE RIVER PHARM GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine currently has no clear and effective drugs for the treatment of fatty liver. Because fatty liver is often accompanied by obesity, diabetes, hyperlipidemia, etc., its treatment is mainly aimed at different risk factors, mainly lipid-lowering and liver-protecting drugs, supplemented by diet, Exercise therapy lacks specific drugs, and the treatment effect is not good; while traditional Chinese medicine has its unique advantages in the treatment of fatty liver

Method used

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  • Drug compound for treating fatty liver, preparation method and application thereof
  • Drug compound for treating fatty liver, preparation method and application thereof
  • Drug compound for treating fatty liver, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] 5 parts of Shouwu, 10 parts of Salvia miltiorrhiza, 20 parts of Alisma, 20 parts of hawthorn, 10 parts of Yinchen, 18 parts of Prunella vulgaris, 10 parts of Gui Jianyu, add 50-70% ethanol with a volume weight ratio of 6-10 times Extract 1-3 times, 1-2h each time, and concentrate; 15 parts of turmeric, 5 parts of Cyperus officinalis extract volatile oil, and then add 5 parts of seaweed, 15 parts of fried silkworm, 15 parts of Polygonatum chinensis to the volume weight ratio of 6- Decoction with 10 times the amount of water for 1-3 times, 1-2 hours each time, combine the decoction liquid, filter, concentrate the filtrate to a relative density of 1.25-1.35, dry, and pulverize it into extract powder; take the extract powder above , Add dextrin or lactose or starch or magnesium stearate and steviol to the volatile oil, mix well, granulate and press into tablets to make tablets.

Embodiment 2

[0038] 5 parts of Shouwu, 10 parts of Salvia miltiorrhiza, 20 parts of Alisma, 20 parts of hawthorn, 10 parts of Yinchen, 18 parts of Prunella vulgaris, 10 parts of Gui Jianyu, add 50-70% ethanol with a volume weight ratio of 6-10 times Extract 1-3 times, 1-2h each time, and concentrate; 15 parts of turmeric, 5 parts of Cyperus officinalis extract volatile oil, and then add 5 parts of seaweed, 15 parts of fried silkworm, 15 parts of Polygonatum chinensis to the volume weight ratio of 6- Decoction with 10 times the amount of water for 1-3 times, 1-2 hours each time, combine the decoction liquid, filter, concentrate the filtrate to a relative density of 1.25-1.35, dry, and pulverize it into extract powder; take the extract powder above , volatile oil, add dextrin or lactose or starch or magnesium stearate and steviol, mix well, granulate, namely make granules.

Embodiment 3

[0040] 10 parts of Shouwu, 15 parts of Salvia miltiorrhiza, 15 parts of Alisma orientalis, 15 parts of hawthorn, 15 parts of Yinchen, 12 parts of Prunella vulgaris, 15 parts of ghost arrow feathers, add 50-70% ethanol with a volume-to-weight ratio of 6-10 times Extract 1-3 times, 1-2h each time, and concentrate; 10 parts of turmeric and 10 parts of Cyperus officinalis extract the volatile oil, and then add 10 parts of seaweed, 10 parts of fried silkworm, and 10 parts of Polygonatum chinensis in a volume-to-weight ratio of 6- Decoction with 10 times the amount of water for 1-3 times, 1-2 hours each time, combine the decoction liquid, filter, concentrate the filtrate to a relative density of 1.25-1.35, dry, and pulverize it into extract powder; take the extract powder above , volatile oil, add dextrin or lactose or starch or magnesium stearate and steviol, mix well, granulate, namely make granules.

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Abstract

The invention discloses a drug compound for treating fatty liver, a preparation method and an application thereof. The active ingredient of the compound is prepared from the following bulk drugs in parts by weight: 10-20 parts of oriental wormwood, 6-18 parts of selfheal, 10-20 parts of salviae miltiorrhizae, 10-20 parts of hawthorn, 10-20 parts of ramuli euonymi, 5-15 parts of sunburned silkworm, 5-15 parts of alga, 10-20 parts of rhizoma alismatis, 5-15 parts of prepared fleece-flower root, 5-15 parts of prepared sealwort, 5-15 parts of prepared nutgrass galingale rhizome and 5-15 parts of zedoary. The drug compound for treating fatty liver has the effects of tonifying liver and kidney, clearing heat, transferring dampness, reducing phlegm and removing stasis and is used for treating fatty liver. The drug compound is conveniently taken, acts smoothly and stably, has a curative effect, has dosage form stability, controllable control and no toxic or side effect and can meet the requirement of the patient.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a medicinal composition for treating fatty liver prepared by using traditional Chinese medicine as a raw material, and a preparation method and application thereof. Background technique [0002] Fatty liver disease (FLD), referred to as fatty liver, is a series of clinical symptoms caused by lipid metabolism disorders and dynamic balance disorders in the liver caused by various etiologies, resulting in lipid accumulation in liver cells and steatosis of liver cells. pathological syndrome. The incidence of fatty liver in my country is increasing year by year. The incidence of fibrosis is as high as 25%, and about 1.5%-8.0% of patients can develop liver cirrhosis. Therefore, active prevention and treatment of fatty liver has important clinical significance to prevent the development of chronic liver disease and improve the prognosis. [0003] At pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/16A61K35/64
CPCA61K36/8905A61K36/8969A61K36/9066A61K35/63A61K36/02A61K36/282A61K36/37A61K36/536A61K36/537A61K36/704A61K36/734A61K36/884A61K2236/331A61K2236/33A61K2236/51A61K2300/00
Inventor 宋敏谭琴姚仲青汪斌何倩灵赵静李娜陈钟
Owner YANGTZE RIVER PHARM GRP CO LTD
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