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Medicine composition for treating or preventing adiposis and metabolic syndrome and application thereof

A technology for metabolic syndrome and composition, which is applied in the directions of drug combination, metabolic diseases, and medical preparations containing active ingredients, etc., to achieve the effect of reducing treatment costs, reducing the frequency of medication, and reducing the risk of adverse reactions and damage to the body

Inactive Publication Date: 2017-11-03
CHONGQING ZEN PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Therefore, taking orlistat alone has certain risks. An ideal weight loss drug needs to be effective and safe for long-term use without obvious adverse reactions. However, so far, there is no drug that can fully meet the above requirements

Method used

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  • Medicine composition for treating or preventing adiposis and metabolic syndrome and application thereof
  • Medicine composition for treating or preventing adiposis and metabolic syndrome and application thereof
  • Medicine composition for treating or preventing adiposis and metabolic syndrome and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The compound tablet prepared by embodiment 1 pharmaceutical composition

[0038]

[0039] Preparation method: Weigh orlistat, voglibose, microcrystalline cellulose and starch to make powder and mix uniformly; add appropriate amount of 50% ethanol solution to the mixed powder and mix uniformly to make soft material; pass 18 Make wet granules through a mesh sieve, dry at 30-35°C, granulate with a 20-mesh sieve, mix with magnesium stearate, and press into tablets.

Embodiment 2

[0040] The compound tablet prepared by embodiment 2 pharmaceutical composition

[0041]

[0042] Preparation method: except that the prescription is different, the preparation method is the same as in Example 1.

Embodiment 3

[0043] The compound tablet prepared by embodiment 3 pharmaceutical composition

[0044]

[0045] Preparation method: except that the prescription is different, the preparation method is the same as in Example 1.

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PUM

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Abstract

The invention belongs to the field of medicines, and particularly relates to a medicine composition for treating or preventing adiposis and metabolic syndrome and application thereof. Active ingredients of the medicine composition are orlistat and voglibose, wherein the mass ratio of the orlistat to the voglibose is (10 to 30) to 0.1. According to the medicine composition, the metabolism and endocrine system drug voglibose is creatively combined with the conventional antiobesity drug orlistat for use, and the purposes of remarkably reducing postprandial blood sugar and enabling the postprandial blood sugar to be stable can be realized by greatly reducing the dosage of the single drugs, so that the pressure of islet cells is lowered, and the probability of diabetic complication of an adiposis patient is retarded or prevented. When the composition is used for treating or preventing the adiposis and the metabolic syndrome, not only obvious advantage is shown on the treating and preventing of the adiposis, but also effective control is performed on the indexes of blood fat, blood glucose and the like, and the positive treating and preventing effects are realized on the metabolic syndrome.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition for treating or preventing obesity and metabolic syndrome and its application. Background technique [0002] Obesity has become a worldwide problem that endangers human health. The current methods of weight loss treatment include lifestyle adjustment, behavioral therapy, drug therapy and weight loss surgery. As far as obesity is concerned, diet and exercise are still the most commonly used strategies, but unfortunately, this approach has proven ineffective in most cases and is difficult to be adhered to by patients. Therefore, effective and safe weight loss drugs have broad application prospects in the context of the increasing prevalence of obesity. [0003] Obesity is the result of a combination of factors and is one of the symptoms of metabolic syndrome. Metabolic syndrome refers to the pathological state of metabolic disorders of proteins, fa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/365A61K31/133A61P3/10A61P3/04A61P3/00
CPCA61K31/365A61K31/133A61K2300/00
Inventor 邱宗荫肖玉梅李宏伟罗礼平贺耘于国锋
Owner CHONGQING ZEN PHARMACEUTICAL CO LTD
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