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Medicine for preventing and treating hip replacement sequela as well as preparation method and application thereof

A technology for hip replacement and sequelae, applied in the field of medicine, can solve the problems of prolonged course of disease, repeated attacks, prolonged unhealing, etc., and achieves the effects of short healing time, less recurrence, and definite curative effect.

Inactive Publication Date: 2018-01-16
THE WENDENG OSTEOPATH HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing treatments have disadvantages such as poor effect, long-term non-healing, prolonged course of disease, difficulty in curing, recurrent attacks, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] In an embodiment of the present invention, a medicine for preventing and treating sequelae of hip joint replacement comprises the following raw materials: 15 kg of celery, 7 kg of Shuibazhi, 11 kg of rue, and 1 kg of Radix Polygoni Multiflori.

[0027] Grind celery and water cypress branches, pass through a 60-mesh sieve, and then soak them in 50% ethanol aqueous solution with a volume concentration three times the mass of the two for 2 hours, then microwave extraction twice, the microwave power is 600W, 10 minutes each time, The extracts were combined and dried at 55°C to obtain mixture A. The Radix Polygoni Multiflori was crushed, passed through a 100-mesh sieve, and deionized water 10 times its mass was added for ultrasonication for 50 minutes. After ultrasonication, it was centrifuged to obtain the supernatant; the ultrasonic temperature was 70°C, and the ultrasonic frequency was 700W. The centrifugal speed is 3000r / min, and the centrifugal time is 5min. Crush the ...

Embodiment 2

[0029] In an embodiment of the present invention, a medicine for preventing and treating sequelae of hip joint replacement comprises the following raw materials: 25 kg of celery, 15 kg of water cypress, 19 kg of rue, and 5 kg of Radix Polygoni Multiflori.

[0030] Grind the celery and water cypress branches, pass through a 80-mesh sieve, and then soak them in 50% ethanol aqueous solution with a volume concentration 4 times the mass of the two for 2.5 hours, then microwave extraction twice, the microwave power is 600W, 15 minutes each time , Combine the extracts and dry at 60°C to obtain mixture A. The Radix Polygoni Multiflori was crushed, passed through a 120-mesh sieve, and deionized water 12 times its mass was added for ultrasonication for 55 minutes. After ultrasonication, it was centrifuged to obtain the supernatant; the ultrasonic temperature was 72°C, and the ultrasonic frequency was 700W. The centrifugal speed is 3000r / min, and the centrifugal time is 10min. Crush the...

Embodiment 3

[0032] In an embodiment of the present invention, a medicine for preventing and treating sequelae of hip joint replacement comprises the following raw materials: 18 kg of celery, 9 kg of water cypress branch, 13 kg of rue, and 2 kg of Radix Polygoni Multiflori.

[0033] Grind the celery and water cypress branches, pass through a 80-mesh sieve, and then soak them in 50% ethanol aqueous solution with a volume concentration 4 times the mass of the two for 2.5 hours, then microwave extraction twice, the microwave power is 600W, 15 minutes each time , Combine the extracts and dry at 60°C to obtain mixture A. The Radix Polygoni Multiflori was crushed, passed through a 120-mesh sieve, and deionized water 12 times its mass was added for ultrasonication for 55 minutes. After ultrasonication, the supernatant was obtained by centrifugation; the ultrasonic temperature was 71°C, and the ultrasonic frequency was 700W. The centrifugal speed is 3000r / min, and the centrifugal time is 10min. C...

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Abstract

The invention discloses a medicine for preventing and treating hip replacement sequela as well as a preparation method and application thereof. The medicine comprises the following raw materials in parts by weight: 15-25 parts of pleurospermum camtschaticum, 7-15 parts of myricaria prostrate, 11-19 parts of ruta graveolens and 1-5 parts of radix cynanchi bungei. The preparation method comprises the following steps: grinding pleurospermum camtschaticum and myricaria prostrate, soaking into an aqueous solution of ethanol, performing microwave extraction, merging the extracting solution, and drying to prepare a mixture A; grinding the radix cynanchi bungei, adding deionized water for performing ultrasonic treatment, and taking the supernatant; grinding the ruta graveolens, adding the deionized water to be heated and stirred, adding the deionized water to heat, seal and stir, centrifuging, and removing the precipitate to obtain a ruta graveolens solution; and mixing the materials to perform ultrasonic treatment, and stirring to be dry, thereby obtaining the product. The medicine disclosed by the invention is capable of preventing and treating deep venous thrombosis after the hip replacement operation and further treating hip joint pain or gonitis, is high in safety performance, exact in curative effects, fast in efficacy and safe and does not have any toxic or side effect.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a medicine for preventing and treating sequelae of hip joint replacement and its preparation method and application. Background technique [0002] With the continuous maturity of hip arthroplasty, it has increasingly become the primary means of clinical treatment of femoral neck fractures, femoral head necrosis, osteoarthritis and other femoral diseases, and has gradually been accepted and promoted by patients and medical workers. However, the formation of deep venous thrombosis in the lower extremities seriously affects the recovery of patients after operation, and even endangers the lives of patients. At present, reports of lower extremity deep vein thrombosis after hip replacement have attracted more and more attention. The current treatment has disadvantages such as large side effects and poor curative effect, which is not conducive to the cure of patients after hip replace...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/75A61P7/02A61P19/02A61P29/00
Inventor 王艺钧邹德宝李磊周纪平鞠海洋姜红江
Owner THE WENDENG OSTEOPATH HOSPITAL
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