Nano-diamond modified liquid band aid and preparation method thereof

A nano-diamond and band-aid technology, applied in the medical field, can solve problems such as human health hazards, and achieve the effects of no skin irritation, reduced scar area, and good biocompatibility

Inactive Publication Date: 2018-01-19
THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Liquid Band-Aids often contain silver substances, which use silver to sterilize bacteria, but silver will enter the human body with blood circulation after long-term use, causing harm to human health

Method used

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  • Nano-diamond modified liquid band aid and preparation method thereof
  • Nano-diamond modified liquid band aid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A nano-diamond modified liquid band-aid, made of the following raw materials in parts by weight: 15 parts of film-forming substances, 20 parts of ethyl acetate, 40 parts of ethanol, 4 parts of propylene glycol, 6 parts of polydimethylsiloxane, and medical vaseline 7 parts, 4 parts of modified nano-diamond, 8 parts of cattail extract.

[0028] The film-forming substance is a mixture of low-nitrogen nitrocellulose and chitosan, and the mass ratio of the two is 0.4:0.6.

[0029] Described modified nano-diamond is made by following steps:

[0030] i) first place the nano-diamonds in a NaOH solution with a concentration of 15% and ultrasonically clean them for 10 minutes, stir them at a speed of 150 rpm, and wash them repeatedly with deionized water until the pH=7;

[0031] ii) Place the nano-diamonds treated in step a in a dilute nitric acid solution with a concentration of 30% and stir for 50 min at a speed of 50 rpm, and repeatedly wash with deionized water until pH=7; ...

Embodiment 2

[0042] A nano-diamond modified liquid band-aid, made of the following raw materials in parts by weight: 20 parts of film-forming substances, 15 parts of ethyl acetate, 46 parts of ethanol, 5 parts of propylene glycol, 6 parts of polydimethylsiloxane, and medical vaseline 4 parts, 2 parts of nano-diamond, 4 parts of cattail extract.

[0043] The film-forming substance is a mixture of low-nitrogen nitrocellulose and chitosan, and the mass ratio of the two is 0.6:0.4.

[0044] Described modified nano-diamond is made by following steps:

[0045] i) first place the nano-diamonds in a NaOH solution with a concentration of 20% and ultrasonically clean them for 15 minutes, stir them at a speed of 100 rpm, and wash them repeatedly with deionized water until the pH=7;

[0046] ii) placing the nano-diamonds treated in step a in a dilute nitric acid solution with a concentration of 35% and stirring at a speed of 60 rpm for 15 min, and repeatedly washing with deionized water until pH=7; ...

Embodiment 3

[0053] A nano-diamond modified liquid band-aid, made of the following raw materials in parts by weight: 20 parts of film-forming substances, 10 parts of ethyl acetate, 50 parts of ethanol, 3 parts of propylene glycol, 2 parts of polydimethylsiloxane, and medical vaseline 7 parts, 4 parts of nano-diamond, 8 parts of cattail extract.

[0054] The film-forming substance is a mixture of low-nitrogen nitrocellulose and chitosan, and the mass ratio of the two is 0.5:0.5. :

[0055] The preparation method of the extract of the rhododendron extract and the modified nano-diamond is the same as that in Example 1.

[0056] The preparation method of the nano-diamond modified liquid band-aid is the same as in Example 1.

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Abstract

A nano-diamond modified liquid band aid is prepared from raw materials in parts by weight as follows: 15-20 parts of a film forming material, 10-20 parts of ethyl acetate, 40-50 parts of ethanol, 3-5parts of propylene glycol, 2-6 parts of polydimethylsiloxane, 4-7 parts of medical vaseline, 4-8 parts of a cattail spike extract and 2-4 parts of modified nano-diamond, wherein the film forming material, ethyl acetate, ethanol, propylene glycol, polydimethylsiloxane and the medical vaseline are taken as basic raw materials, the cattail spike extract and the modified nano-diamond are taken as active ingredients, and the sum of parts of the basic raw materials and the cattail spike extract by weight is 100. The invention further discloses a preparation method of the nano-diamond modified liquidband aid. Compared with conventional band aids, the liquid band aid is convenient to use, has good antibacterial and anti-inflammatory functions and has no irritation or toxicity to skin, external wounds in any shape and in any position can be more conveniently treated, and the liquid band aid can rapidly form a film and has the efficacy of stopping bleeding, diminishing inflammation, relieving pain and promoting blood circulation to remove blood stasis.

Description

technical field [0001] The invention belongs to the field of medical technology, and in particular relates to a nano-diamond modified liquid band-aid and a preparation method thereof. Background technique [0002] Band-aid is a necessary medical item in the family first aid kit. It is widely used to treat small wounds on the human body. It is also more convenient to use. Generally, band-aids are composed of adhesive tape and sterile gauze. When using them, first use alcohol or disinfectant to simply disinfect the wound. , and then put the band-aid on the wound, and finally use the body's own wound repair function to restore the wound. However, the use of Band-Aids also has disadvantages, such as sticking to the wound for a long time, it is easy to cause the skin near the wound to turn white, and when the Band-Aid needs to be replaced many times, it is easy to cause secondary damage to the wound. In addition, the Band-Aid has poor air permeability and secretes The blood seru...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K47/38A61K47/36A61K47/34A61K36/88A61P17/02A61K33/44
Inventor 李真珍李骥赵占正肖静
Owner THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
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