58results about How to "Rapid coagulation" patented technology

A flexible infrared delivery apparatus useful for endoscopic infrared coagulating of human or animal blood and tissue or for other uses employs a source of infrared radiation which is not a laser and an elongated flexible fiber optic member which transmits radiation from the source to a contact portion at a distal end of the member and to a material such as human or animal tissue proximate the contact portion. The elongated member has an outer diameter which enables it to be inserted into and through an accessory channel of an endoscope to view the human or animal tissue or material to be treated with infrared radiation. A connector on the proximal end of the member allows the elongated member to be quickly connected to and disconnected from the apparatus where the member is aligned for receiving infrared radiation from the source. The contact portion defines a size, direction and shape of a radiation delivery area from the member to the human or animal tissue or material proximate the contact portion.

The invention relates to a staged membrane bioreactor device, for treating sewage or micro-polluted source water, with a water container, pertaining to the environmental protection technology field. The device consists of a half-reaction zone, an anaerobic reaction zone, an aeration reaction zone and a pure water zone. The half-reaction is communicated with the bottom of the aeration zone, the bottom of the half-reaction is provided with an empty valve, one side of the half-reaction zone has a water inlet pump, the inside of the half-reaction has an internal ring filled with stuff, and the top of the half-reaction is provided with a stirrer, and the effluent of the half-reaction automatically flows into the anaerobic reaction zone. The top of the anaerobic reaction zone is provided with a stirrer, the bottom thereof is provided with a sludge empty valve, and a sludge empty device is shaped like a horn mouth and positioned in the anaerobic reaction zone, and the top of the anaerobic reaction zone is provided with a drug feeding mouth. The bottom of the aeration reaction zone has an internal return pump, the lower part of the aeration reaction zone is provided with an aeration pipe with an air inlet positioned at one side of the aeration reaction zone, and a fan is connected to the aeration pipe through the air inlet; the top of the aeration reaction zone is provided with an overflow pipe, the bottom of the aeration reaction zone is provided with an empty valve, while the middle is provided with a membrane component. The pure water zone is divided into two units, and the inside of each unit is provided with an effluent valve. The invention has the advantages of good effluent quality, multi purposes, small land occupancy, flexible and convenient using method, and is applied to the treatment of domestic sewage and micro-polluted source water, and can widen and facilitate the application of membrane bioreactor water treatment and water resource reutilization technique.

A synthetic leather is made by a impregnating a non-woven or woven textile with an aqueous polyurethane dispersion comprised of a nonionizable polyurethane and an external stabilizing surfactant. The impregnated textile is then exposed to water containing a coagulant for a coagulation time sufficient to coagulate the dispersion. The method may be used to form a synthetic leather having excellent wet ply adhesion and may contain an insoluble multivalent cation organic acid.

The invention discloses a method for preparing a high-viscosity chitosan quick hemostatic patch. The method comprises the following steps: preparing chitosan gel from high-viscosity chitosan having a deacetylation degree in the range from 80% to 90%, drying the chitosan gel and then immersing one single side of the chitosan gel into a mixed solution of chloroacetic acid and isopropanol for carboxymethylation, and then soaking the chitosan gel into a 30% glycerol solution for 30 minutes and then draining; and finally, carrying out a cross-linking reaction by using a calcium chloride solution so as to introduce calcium ions and thrombin, and then carrying out vacuum freeze-drying, thereby obtaining the high-viscosity chitosan quick hemostatic patch. Raw materials used for the process of the method are low in cost; the process is simple and convenient, and short in period; the obtained chitosan hemostatic patch is high in adhesiveness, and capable of quickly stopping bleeding of a wound under the promotion effect of the calcium ions and the thrombin.

The invention provides a hybrid fiber sponge with hemostasis and wound repair functions and a preparation method thereof. The hybrid fiber sponge is formed by processing after soaking a freeze-dried sponge in an ethanol solution of 1-ethyl-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide, wherein the freeze-dried sponge is formed by freeze-drying hydrogel formed by crosslinking polyphenol modified chitosan and a protein material and has a composite three-dimensional network structure; and in the process that the freeze-dried sponge is soaked in the ethanol solution of 1-ethyl-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide, carboxyl and amino in the freeze-dried sponge form amido bonds, and meanwhile, the protein material in the freeze-dried sponge are denatured to form beta folds, so that the hybrid fiber sponge is of a porous structure. The hybrid fiber sponge provided by the invention can take effects of inhibiting bacteria and promoting tissue regeneration while stopping bleeding, and is suitable for various bleeding models such as body surface oppression bleeding and in-vivo non-oppression bleeding.

The invention discloses a stancher and a preparation method thereof. The stancher comprises the following components by weight: 1.5 to 15 portions of aizoon stonecrop root, 3.5 to 35 portions of bletilla striata, 3.5 to 35 portions of parched Pollen Typhae, 2 to 20 portions of sanguisorba carbon, 3.5 to 35 portions of crinis carbonisatus, 5 to 50 portions of red madder root, 2 to 20 portions of frankincense, 2 to 20 portions of myrrh, 1.5 to 15 portions of dragon's blood, 5 to 50 portions of halloysitum rubrum, 5 to 50 portions of drgon's bones and 0.3 to 3 portions of borneol. The stancher has the advantages of high healing effect, convenient use, fast blood assuaging, pain assuaging, tissue regeneration promoting and healing, low medical treatment cost, and the like, the preparation method is simple, and the usage of the stancher is convenient.

A one-piece stent implanter comprises a front handle and a rear handle; the front end of the front handle is provided with an outer pipe whose top is flexibly connected with a cautery tip, the outer pipe is internally provided with a middle pipe and a stent; the rear handle includes a stainless steel pipe for supporting and an inner pipe positioned in the stainless steel pipe; one end of the stent is close to the cautery tip, with a certain gap kept; when the front handle is retreated along the stainless steel pipe, the outer pipe simultaneously retreats and separates from the cautery tip, positions of the middle pipe and the rear handle remain unchanged, and the stent is automatically released.

The invention discloses a composite material with a rapid blood coagulation effect and a preparation method thereof and belongs to the technical field of biological medicines. The composite material with the rapid blood coagulation effect is prepared from the following raw materials in parts by mass: 8 to 20 parts of chitosan, 7 to 14 parts of salicylaldehyde, 8 to 16 parts of 2-aminoisonicotinic acid, 1.5 to 3.5 parts of ferrous sulfate, 3 to 5 parts of dopa and 10 to 15 parts of disodium hydrogen phosphate. The prepared composite material with the rapid blood coagulation effect has good product stability and high biological safety, has a remarkable effect on blood coagulation, and is simple in process and easy to industrially produce.

The invention relates to a postoperative tourniquet for percutaneous coronary intervention treatment. The postoperative tourniquet for percutaneous coronary intervention treatment comprises a main fixing plate, wherein a hemostasis module is arranged on the main fixing plate, and fixing adhesive tapes are respectively connected to two sides of the main fixing plate. The hemostasis module comprises a supporting plate and a hemostasis material layer, wherein the supporting plate is arranged on the main fixing plate, the hemostasis material layer is arranged on the supporting plate and comprises two PVA layers and a collagen layer arranged between the PVA layers. The postoperative tourniquet for percutaneous coronary intervention treatment can achieve quick hemostasis, the working amount of mecical workers can be reduced, and a simple hemostasis device can be replaced. The postoperative tourniquet is convenient to use, a hemostasis material is made of an expansible material, can intelligently exert pressure without pressure regulation, misoperation is avoided, and errhysis is decreased to the most degree.

The invention discloses a multifunctional mesoporous biological material and a preparation method thereof. The amorphous glass state particulate matter is composed of an external wrapping mesoporous structure and an internal cabbage structure, the diameters of external wrapping annular mesopores are 5-25 nm, and the gap pitch of the internal cabbage structure is 30-200 nm. The main component of the mesoporous biological material is SiO2-B2O3-CaO, and the mesoporous biological material also contains P2O5, CuO, MgO, ZnO, SrO, Li2O, Na2O and / or K2O. A unique mesoporous particle material is prepared by using a microstructure directing agent and adopting a sol-gel method, and the preparation process is simple. The material is used for arterial and venous hemostasis and promoting healing or regenerative repair of soft tissue and bone tissue wounds, has good histocompatibility, and is a biomedical material capable of adjusting inflammatory response in wounds and preventing and treating pathogenic bacteria infection.

The invention discloses a preparation method of a chitosan-agar oligosaccharide porous ball hemostatic material. The method comprises the following steps of: S1, preparing a chitosan-agar oligosaccharide compound solution; S2, adding a crosslinking agent 1,3-diepoxy glyceryl ether glycerinum into a compound alcohol solution, dropwise adding the chitosan-agar oligosaccharide compound solution into the compound alcohol solution containing the 1,3-diepoxy glyceryl ether glycerinum under the ultrasonic power of 130-150W, after dropwise addition, stopping ultrasonic treatment, and stirring the mixture for 30min at 600-800rpm; and S3, filtering balls, and washing, freezing and drying the balls. The hemostatic material prepared by the invention is good in biocompatibility and safe and non-toxic, can quickly accelerate blood clotting and has efficient hemostatic activity, has a certain volume, and is unlikely to enter blood to induce a thrombus risk. Meanwhile, the material has excellent wound adaptability, and is in particular suitable for bleed stopping of wounds which are deep, narrow and irregular. The preparation disclosed by the invention is simple in preparation process and easy for industrial production.

The invention discloses a method for treating low-temperature and low-turbidity sewage by PAC, which comprises the following steps: adjusting the pH value of to-be-treated sewage to maintain the pH value of the to-be-treated sewage between 6.0 and 9.0; adding zeolite powder into the to-be-treated sewage, and stirring the sewage for 1 hour underwater at the rotating speed of 100-150 r / min; adding kaolin into the to-be-treated sewage, and stirring the sewage for 1 minute underwater at the rotating speed of 60 r / min; adding polyaluminum chloride while stirring the sewage at the rotating speed of60 r / min, and standing the sewage until the floc is completely settled. Zeolite powder is added into the sewage with rapid stirring, so that ammonia nitrogen in water can be removed, dissolved oxygenis increased, meanwhile, the total alkalinity of a water body is improved, and the water quality is stabilized. Kaolin is used as a coagulant aid and is added into water firstly, so that the effectivecollision probability among particles is increased, suspended solids in water are coagulated quickly after polyaluminum chloride is added, compact floc is formed, and alum floc is large in mass and high in settling speed.

The invention discloses a fuse insulation protection sleeve, which comprises pin fixation cylinder, connecting cylinders and an insulation protection cover. The two ends of the insulation protection cover are connected with the pin fixation cylinders through the connecting cylinders respectively. When a fuse is installed, the fuse is arranged in the insulation protection cover, and independent pins at the two ends of the fuse are exposed; then, the connecting cylinders are clamped at the two ends of the insulation protection cover respectively, so that the position of the fuse is fixed; the two independent pins of the fuse are inserted into first pin through holes in the two fixation cylinders, and the end parts of the independent wire pins are clamped by a spring piece so as to be conducted with a circuit; in the whole fuse installation process, the fuse is connected to the circuit without a hinging and welding mode, and thus the fuse is convenient to install and replace; and a sleevecore is made of a high-heat-conductivity insulating composite material, and the high-heat-conductivity insulating composite material comprises a heat conduction layer and insulating layers arranged on the two faces of the heat conduction layer, wherein the insulating layers have good heat conduction capacity, heat resistance and electric insulativity.

The invention discloses a preparation method of a chitosan-agar oligosaccharide porous ball hemostatic material. The method comprises the following steps of: S1, preparing a chitosan-agar oligosaccharide compound solution; S2, adding a crosslinking agent 1,3-diepoxy glyceryl ether glycerinum into a compound alcohol solution, dropwise adding the chitosan-agar oligosaccharide compound solution into the compound alcohol solution containing the 1,3-diepoxy glyceryl ether glycerinum under the ultrasonic power of 130-150W, after dropwise addition, stopping ultrasonic treatment, and stirring the mixture for 30min at 600-800rpm; and S3, filtering balls, and washing, freezing and drying the balls. The hemostatic material prepared by the invention is good in biocompatibility and safe and non-toxic, can quickly accelerate blood clotting and has efficient hemostatic activity, has a certain volume, and is unlikely to enter blood to induce a thrombus risk. Meanwhile, the material has excellent wound adaptability, and is in particular suitable for bleed stopping of wounds which are deep, narrow and irregular. The preparation disclosed by the invention is simple in preparation process and easy for industrial production.

The invention discloses a preparation method of a hemostatic material based on fibrin gel. The preparation method comprises the following steps: A. dissolution of bovine fibrinogen: at the temperature of 30-50 DEG C, bovine fibrinogen is dissolved by the use of a 0.9% NaCl solution so as to obtain a bovine fibrinogen solution with the concentration of 5-30 mg / Ml; B. dissolution of human thrombin: at the temperature of 30-50 DEG C, human thrombin is dissolved by the use of 330-660 mol / L of a CaCl2 solution so as to obtain a human thrombin solution with the concentration of 3-7 * 104 unit / L; and C. synthesis of gel: at the temperature of 30-50 DEG C, the fibrinogen solution obtained in the Step A and the thrombin solution obtained in the Step B are mixed according to the volume ratio of 1:1-5 so as to obtain mixed liquor; and the mixed liquor is dropped on gauze and then reacts on a shaker of 30-50 DEG C for 4-12 h. The hemostatic material prepared by the method has a good hemostatic effect, has good biocompatibility, can promote formation of granulation tissues and epithelial tissues and speed up healing and repairing of skin tissues, is beneficial to observation of wounds and healing situation, and is convenient for diagnosis and treatment of wounds.

The invention discloses a hemihydrate building gypsum coagulant and a preparation method and application thereof. The coagulant comprises mother liquor and powdery master batch, wherein the powdery master batch comprises soluble calcium salts; and the mother liquor is a sulfuric acid solution. The soluble calcium salts are matched with dilute sulfuric acid with a certain concentration to improve the concentration of calcium ions and sulfate ions in the fluid phase of the hemihydrate gypsum slurry so as to rapidly reach the supersaturation degree of crystallization of calcium sulfate dihydrate,finally, a large amount of primary micro calcium sulfate dihydrate crystal nuclei are formed in the solution of the hemihydrate gypsum slurry, the obtained crystal nuclei are smaller in size and strong in induced crystallization effect, so that quick hardening of the hemihydrate building gypsum is achieved; the preparation process is simple, the using method is simple and easy to operate, technical support and theoretical guidance are provided for the hemihydrate gypsum coagulant with low cost and high coagulation promoting effect, and the method has good application prospect.

Devices and methods can be used to deliver thermal therapy to treat tissue. For example, this document provides devices and methods for treating varices, varicosity, other bleeding vessels, polyps, and cancer using microwave-delivered thermal therapy in a minimally invasive fashion. In some embodiment's provided herein, a multidirectional thermal therapy that does not injure surface tissues but causes endothelial injury and coagulation is described. In some implementations, varices are suctioned into a cup that is configured to deliver thermal therapy to the varices, resulting in coagulation.

The invention discloses a chitosan hemostatic gel and a preparation method thereof. The chitosan hydrogel is glycidyl ether modified chitosan dissolved in water. For the deficiency that the blood coagulation rate of the common chitosan material is relatively slow, a hydrophobic chitosan derivative is prepared by introducing the alkane long chain in the invention; when in contact with blood, the hydrophobic group thereof can promote erythrocyte aggregation to realize rapid blood coagulation; the chitosan hemostatic gel in the invention is the gel dosage form, which is convenient to use and carry; and the preparation method adopted in the invention is simple and convenient in process and convenient to operate, and can be used for large-scale industrial production.

The invention discloses a pantograph hemostatic structure and a hemostatic device, wherein the pantograph hemostatic structure comprises a hemostatic material external application film and an self-adaptive pantograph unfolding structure. The self-adaptive pantograph unfolding structure consists of a pantograph structure unit and a supporting rod. The inner end of the pantograph structure unit is fixed on the supporting rod, the hemostatic material external application film is adhered and fixed on the outer side of the self-adaptive pantograph unfolding structure, the pantograph structure unitis composed of pantograph units and an elastic element, the pantograph unit is formed by connecting the centers of two rods. The two ends of the elastic element are respectively connected to the connecting hinge of the adjacent pantograph structure units. When in use, the hemostatic structure is injected into a wound, the elastic element release the elasticity and can expand the self-adaptive pantograph unfolding structure in a radial direction, and the corresponding deformation is generated according to the wound shape, and the hemostatic material external application film is driven to fit the wound surface, so that the rapid hemostasis function is achieved.

Beer and beer-based beverages in which the content of polyphenols and / or silicon is enhanced by the addition of polyphenols of Silybum marianum in a water-soluble form comprising their mixture with at least one basic amino acid or aminohexitol in the molar ratio of from 1:1 to 1:2 and / or by the addition of colloidal silicon dioxide in a water-soluble form and comprising its mixture with at least one basic amino acid or aminohexitol in the molar ratio of from 1:3 to 1:4. A method of modification of the content of these substances in beverages is also described.

The invention provides an electrotome, a high-frequency electrotome and a connecting process of the electrotome in the high-frequency electrotome, the high-frequency electrotome comprises a handle assembly, an outer sheath pipe assembly, a traction assembly and the electrotome, the electrotome contains a tungsten material, and a knife body of the electrotome is arranged at one end of the outer sheath pipe assembly in a penetrating mode; the other end of the outer sheath pipe assembly is connected with the handle assembly; the traction assembly is arranged in the outer sheath pipe assembly in apenetrating mode and comprises a first connecting pipe, a soft wire, a second connecting pipe, a rotating shaft and a catheter which are connected in sequence, the soft wire is made of stainless steel materials or nickel-titanium wire materials, and the end of the soft wire and the knife body of the electrotome are both fixed in the first connecting pipe; and the catheter is connected with an electrode arranged in the handle assembly. According to the invention, the phenomena of smoke generation and mucous film tissue knife sticking during cutting are reduced.

A nano-diamond modified liquid band aid is prepared from raw materials in parts by weight as follows: 15-20 parts of a film forming material, 10-20 parts of ethyl acetate, 40-50 parts of ethanol, 3-5parts of propylene glycol, 2-6 parts of polydimethylsiloxane, 4-7 parts of medical vaseline, 4-8 parts of a cattail spike extract and 2-4 parts of modified nano-diamond, wherein the film forming material, ethyl acetate, ethanol, propylene glycol, polydimethylsiloxane and the medical vaseline are taken as basic raw materials, the cattail spike extract and the modified nano-diamond are taken as active ingredients, and the sum of parts of the basic raw materials and the cattail spike extract by weight is 100. The invention further discloses a preparation method of the nano-diamond modified liquidband aid. Compared with conventional band aids, the liquid band aid is convenient to use, has good antibacterial and anti-inflammatory functions and has no irritation or toxicity to skin, external wounds in any shape and in any position can be more conveniently treated, and the liquid band aid can rapidly form a film and has the efficacy of stopping bleeding, diminishing inflammation, relieving pain and promoting blood circulation to remove blood stasis.

The invention provides a hemostatic fabric containing trypsin. The hemostatic fabric contains a molecular sieve fiber compound and the trypsin, wherein the molecular sieve fiber compound contains molecular sieves and fibers, and the molecular sieves are distributed on the surfaces of the fibers and are in direct contact with the surfaces of the fibers; contact surfaces between the molecular sievesand the fibers do not contain binder and are inner surfaces, and the inner surfaces are rough planes, and growth matching coupling is formed between the molecular sieves and the fibers on the inner surfaces. By specifically combining the trypsin with the molecular sieve fiber compound and maintaining relatively high procoagulant activity, the hemostatic fabric with an excellent blood coagulationeffect is obtained. The preparation method of the hemostatic fabric is simple and low in cost, and the hemostatic fabric is convenient to use and can be widely applied to surgical hemostasis.

The invention relates to a preparation method of a starch microsphere and human recombinant tissue factor lipid composite hemostatic material. The preparation method comprises the following steps: dissolving potato starch in deionized water, mixing with emulsified soybean oil according to the mass ratio of water phase to oil phase solution of 1: 2.0-1: 2.5, and forming starch microspheres with mutually condensed hydroxyl groups under the action of an initiator; further dispersing the obtained starch microspheres in anhydrous 1,4-dioxane, modifying with N,N'-disuccinimido carbonate (DSC), adding human recombinant tissue factor lipids, and combining the tissue factors with the starch microspheres in a covalent bonding manner. The starch microsphere and human recombinant tissue factor lipid composite hemostatic material is obtained through centrifugation, cleaning and vacuum drying, and a rapid blood coagulation effect is achieved by utilizing the starting blood coagulation function of tissue factors.

The invention discloses an amorphous silicon-based material as well as a preparation method and application thereof, and the amorphous silicon-based material comprises the following components in parts by mole: 20 to 60 parts of SiO2, 10 to 30 parts of CaO, 5 to 10 parts of MgO, 0.1 to 5 parts of Na2O and 0.1 to 5 parts of K2O. According to the amorphous silicon-based material disclosed by the invention, through synthesis of the raw materials, efficient and rapid hemostasis of the hemostatic material under rapid wetting is realized, and meanwhile, the material has excellent antibacterial and healing-promoting properties while being biodegraded.

The invention relates to an antibacterial efficient hemostatic membrane-like structure disguised bioactive glass nano-composite particle and a preparation method thereof. The bioactive glass nano-composite particle comprises aminated macroporous bioactive glass, bovine serum albumin and chitosan. The preparation method comprises the following steps: taking aminated macroporous bioactive glass, deionized water, bovine serum albumin and chitosan as raw materials, according to a layer-by-layer self-assembly sequence, and through an electrostatic adsorption principle, obtaining the bioactive glass nano composite particle with the disguised membrane-like structure. The preparation process is simple, and no secondary product is generated. The membrane structure disguised porous nano-particles are wrapped by bovine serum albumin with a platelet generation promoting effect and chitosan with an erythrocyte gathering and antibacterial effect, and the membrane structure disguised porous nano-particles can simultaneously activate endogenous and exogenous blood coagulation pathways, quickly form thrombus stopping and wound blocking on a wound surface, reduce the bleeding amount and shorten the bleeding time. The coagulation effect and the biocompatibility of the bioactive glass are improved, the antibacterial performance is also given to the bioactive glass, and the bioactive glass has huge clinical application value.

The invention provides an implantable anti-tumor dressing, which comprises a nanofiber membrane. The outer side of the nanofiber membrane is covered with a hemostatic material, and the hemostatic material is chitosan aerogel; the nanofiber membrane is formed by weaving nanofibers, the nanofibers are set as core-shell composite structures composed of core layers and shell layers,the core layers ofthe nanofibers are prepared by using an anti-tumor drug doxorubicin, and the shell layers of the nanofibers are prepared by using polylactic acid-glycolic acid doped with black phosphorus quantum dots. The invention further provides a preparation method of the implantable anti-tumor dressing. The preparation method of the implantable anti-tumor dressing comprises the steps that a core layer spinning solution is prepared; shell layer spinning solution is prepared; a core-shell structure nanofiber membrane is prepared by using a coaxial electrostatic spinning method; a shell polyacetic acid solution is prepared; and the implantable anti-tumor dressing is prepared. The implantable anti-tumor dressing has outstanding effects in all of hemostatic properties, antibacterial properties, anti-tumordrug release, and photothermal killing of tumor cells and has broad medical prospects.