Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Yeast extract having vasorelaxing effect

A technology for yeast extract and vasodilation, which is applied in the field of food compositions and pharmaceutical compositions, can solve the problems of many side effects, long-term continuous taking, inability to decide whether to take or stop taking them, etc., and achieves the effects of low price and easy production.

Inactive Publication Date: 2018-01-19
KOHJIN CO LTD
View PDF10 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These medicines are mainly used in medical institutions for patients with severe hypertension. Although they are highly effective, they must be taken continuously for a long time, and they cannot decide whether to take them or stop taking them.
Moreover, there are many side effects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Yeast extract having vasorelaxing effect
  • Yeast extract having vasorelaxing effect
  • Yeast extract having vasorelaxing effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] 1. Methods of measuring vascular tension

[0046] a. Reagents and materials

[0047] Rats: Male SD rats (8-11 weeks)

[0048] Buffer: PSS (pH7.4) [NaCl 145, KCl 5, Na 2 HPO 4 1. CaCl 2 2.5, MgSO 4 ·7H 2 O 0.5, glucose 10, HEPES 5(mM)]

[0049] Contraction stimulator: 1.0μM phenylephrine (PE)

[0050] b. Preparation

[0051] PE: Dissolve in PSS to become 10μM

[0052] "Haicunx" YH-15: Dissolved in the prepared 10 μM PE. In the used "Haysense" YH-15, the glutathione content was 19.0% by mass, the adenine content was 0.2% by mass, the adenosine content was 0.1% by mass, and the methylthioadenosine content was 0.4% by mass.

[0053] c. Measurement steps

[0054] After the rat’s thoracic aorta was removed, it was mixed with gas (95% O 2 , 5% CO 2 )Bubbling balance for 45 minutes. Then, the adipose tissue is removed and cut into 2 to 3 mm as a blood vessel ring sample. Place the vascular ring sample on the hook in the Organ Bath filled with 4.5 mL of PSS, and balance with a load of 2 ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Provided is a vasorelaxant from food that has few side effects and is safe for hypertension patients and healthy persons said to have prehypertension. Also provided are foods and beverages including this composition and foods and beverages such as health foods, functional foods, and health supplements. An extract of yeast is used as an active ingredient. A yeast extract obtained by a simple procedure consisting of hot-water treatment, acid or alkali treatment, and enzyme treatment of yeast was discovered to have a superior vasorelaxing effect as a yeast extract.

Description

Technical field [0001] The present invention provides a food composition and a pharmaceutical composition that contain an aqueous solvent extract derived from torula yeast as an effective ingredient and are excellent in vasodilation. Background technique [0002] Because hypertension lacks subjective symptoms, the condition will develop without noticing it, and it may also cause adverse effects on other organs, as a complication may be complicated by various vascular diseases. The main complications include angina pectoris, myocardial infarction, cerebral infarction, decreased renal function, and dissecting aortic aneurysm. Some of these complications are fatal if they develop severely. [0003] As a treatment for hypertension, it includes improving living habits and medication. Improving living habits generally includes diet control, weight loss, alcohol control, moderate exercise, and smoking cessation. Because they do not use drugs, they have less hidden side effects and less...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/06A23L33/14A61K31/52A61K31/7076A61K38/00A61P7/00
CPCA23L33/14A61K31/52A61K31/7076A61K36/06A61K38/00A23V2002/00A23V2200/326A61K38/063A61P9/00A61P9/12
Inventor 佐伯知美大前允人滨泽和弘
Owner KOHJIN CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com