41 results about "Prehypertension" patented technology

The invention discloses a noninvasive continuous human body arterial blood pressure measuring method and equipment. The noninvasive continuous human body central arterial blood pressure measuring method comprises the steps as follows: calculating individualization parameters of a to-be-measured person artery blood vessel network model according to acquired pulse wave forms of radial arteries and brachial arteries; calculating radial artery blood pressure systolic pressure, diastolic pressure and blood pressure wave forms according to radial artery pulse wave speeds and artery blood vessel network parameters; calculating ascending aorta-radial artery transfer functions; further calculating central arterial blood pressure. The noninvasive continuous human body central arterial blood pressure measuring equipment consists of a signal processing and analyzing unit, a pulse wave and motion signal acquisition unit worn on the wrist as well as an electro-cardio and motion signal acquisition unit worn in front of the chest. According to the method and the equipment, electrocardiograms, the radial artery blood pressure, the central arterial blood pressure as well as motions and postures are monitored simultaneously, heart rate and electro-cardio morphological parameters are analyzed in various motion states, artery network model parameters and blood pressure parameters, particularly central arterial pressure wave form parameters, are analyzed, and the method and the equipment have great significance for prevention and control on cardiovascular diseases, particularly for prevention and control on high-risk diseases such as the hypertension, the coronary heart disease and the like.

The present invention relates to methods of treating subjects suffering from pre-hypertension or hypertension by administering to a subject in need of treatment thereof a therapeutically effective amount of at least one xanthine oxidoreductase inhibiting compound or salt thereof.

The invention discloses a cardiovascular and cerebrovascular disease therapeutic apparatus capable of positioning function recovery therapy, preventing hypertension and cardiovascular and cerebrovascular diseases, and carrying out clinic therapy and first-aid, which consists of an oxygen inhalation horizontal exerciser and a massager and utilizes physical and chemical medicine combination treatment; the oxygen inhalation horizontal exerciser consists of a bed body, an oxygen inhalation device and a rotary wheel, for oxygen inhalation, respiratory administration, recovering abdominal breathing function and reducing blood pressure, which is combined with medicine oral administration, and the massager comprises medicine cloth and a massage head for medically massaging rigid muscle and activating blood, which is combined with local medicine injection; the invention is based on treatment principle and method of serious diseases, aims at the cause of hypertension and cardiovascular and cerebrovascular diseases to be function reduction and structural damage which are restricted by each other, and integrates function recovery with existing treatment of medicine, operation, and bypass grafting injury protection which can promote one another. The invention can cure cardiovascular and cerebrovascular diseases by treatment of disease cause.

A computerized health management method and a health management electronic device are provided. The computerized health management method includes the following steps. A blood pressure curve of a user is measured. A systolic pressure and a diastolic pressure of the blood pressure curve are calculated by a microprocessor. A high blood pressure risk level of the user is analyzed by the microprocessor according to the systolic pressure and the diastolic pressure. A cardiovascular disease risk level of the user is analyzed by the microprocessor according to the high blood pressure risk level. A measuring frequency for measuring the blood pressure is suggested to the user by the microprocessor according to the high blood pressure risk level or the cardiovascular disease risk level.

The invention provides application of apigenin in the preparation of a medicine for preventing and treating hemorrhagic cerebrovascular disease and ischemic cerebrovascular disease caused by high blood pressure. The invention indicates that apigenin treatment can decrease the death rate of model mice with hypertensive cerebral hemorrhage by a dosage-dependent method. The apigenin decreases the onset risk of hypertensive cerebral hemorrhage by regulating the genetic expression of cerebrovascular smooth muscle cells.

The invention discloses a novel use of a novel use of growth-differential factor 15 (GDF15) in assessment of first cerebral stroke of a hypertension patient. The GDF15 is used as a marker for assessment of a first cerebral stroke risk of a subject to be detected. The invention also provides a use of a reagent for detecting a GDF15 level in a detection agent or detection system for assessment of a first cerebral stroke risk of a subject to be detected and also provides a detection system for assessment of a first cerebral stroke risk of a subject to be detected. A hypertension cohort population perspective research proves that the hypertensive patient with a high baseline blood plasma GDF15 level has a high risk of first cerebral stroke and cerebral ischemic stroke.

The invention discloses a multifunctional medicine taking device for a patient suffering from a hypertensive chronic disease. The multifunctional medicine taking device comprises a body, wherein a PLC and a voice prompt are arranged on the side surface of the body respectively, the input end of the PLC is electrically connected with the output end of an external power supply, a medicine adding port is formed in the upper surface of the body and is communicated with a medicine storage cavity formed in the body, the lower surface of the medicine storage cavity is communicated with a medicine delivery pipe, a magnetic valve is arranged at the medicine delivery pipe of the internal upper surface of the medicine storage cavity, both the input end of the magnetic valve and the input end of the voice prompt are electrically connected with the output end of the PLC, and a photoelectric counter is arranged on the side surface of the inner wall of the medicine delivery pipe. The multifunctional medicine taking device for the patient suffering from the hypertensive chronic disease is simple in structure, lower in cost, convenient to popularize and promote, convenient to operate, diversified in function and capable of storing solid medicines and liquid medicines, meanwhile can detect the blood pressure of the patient and is convenient to use and high in practicability.

The present application provides methods for treating cardiovascular conditions. The methods can include administering a Transient Receptor Potential Vanilloid 1 (TRPV1) receptor agonist to an epidural space. The methods can be used to treat a variety of conditions such as hypertension, prehypertension, mild hypertension, severe hypertension, refractory hypertension, congestive heart failure and myocardial scarring.

The invention relates to a traditional Chinese medicine composition for controlling hypertension and protecting hypertension target organ against damage, and the traditional Chinese medicine composition is prepared from the following raw material medicines: rhizoma chuanxiong, bupleurum, coptis root, notopterygium, radix saposhnikoviae, prunella spike, cyathula root, polygonatum, concha haliotidis, fried radix scutellariae and herba taxilli. The invention also provides the application of the traditional Chinese medicine composition. The advantages of the traditional Chinese medicine composition are that: the traditional Chinese medicine composition can significantly improve blood pressure indexes of pre hypertension patients, significantly reduces systolic pressure and diastolic pressure level of spontaneously hypertensive rats (SHR), and more important, has significant protective effect against target organ damage in heart, brain and kidney. The traditional Chinese medicine composition used in hypertension early intervention can not only delay the process of hypertension, more important, has the protective effect against target organ damage in hypertension, can be clinically and widely popularized, delays target organ damage, and improves the life quality of the patients.

The invention belongs to the technical field of pharmaceutical preparations comprising an organic active ingredient with an oxygen atom as a hetero atom, in particular to berberine used in the treatment of heart failure or cardiac hypertrophy. Berberine can be used for preventing and treating pressure load-induced cardiac hypertrophy and heart failure, especially for hypertension-induced cardiac hypertrophy and heart failure, and can lower blood pressure, improve a cardiac function, prevent a cardiac remodeling process and prevent a heart from entering a heart failure stage. Berberine can be used as a drug and a health care product for preventing and treating pressure load-induced heart failure, has the dual effects of lowering blood pressure and improving the heart function, is small in side effects, and can reduce the burden of medication on patients.

The invention discloses an application of des-O-methyllasiodiplodin in preparation of a medicament for treating hypertension. Experimental studies show that the des-O-methyllasiodiplodin can well reduce caudal arterial blood pressure, central aortic systolic blood pressure, central aortic diastolic blood pressure, central aortic mean blood pressure and pulse wave velocity of spontaneously hypertensive rats (SHR), improve the artery elastic function, reduce the aortic media thickness and vascular wall collagen fibers and increase the inside diameters of blood vessels, and has a good effect of preventing and treating the hypertension. Obvious adverse response is avoided in the experimental process, and the des-O-methyllasiodiplodin is expected to be developed into a new-generation safe and effective medicament for preventing and treating the hypertension.

A computer system and method is disclosed as a support structure for patients with hypertension or prehypertension to encourage life style changes leading to dietary control, increase exercise and blood pressure control. The method includes automated messages and responses delivered in real time to encourage appropriate actions by the patient. A diary feature is provided for user input of various relevant parameters, such as foods consumed, exercise activities, body weight, blood pressure, and heart rate. The computer system and method may be implemented on a mobile computing device, such as a smart phone or wearable, a conventional personal computer, or a web service. Most functions will be provided on the mobile device, but some housekeeping and data visualization functions may be limited to the personal computer or web service implementations.

The invention relates to a medicinal composition for reducing blood pressure and a preparation method thereof. The composition comprises menthol and a pharmaceutically acceptable carrier, wherein the menthol accounts for 30-50wt% of the medicinal composition. The medicinal composition is prepared from pure natural plate extract menthol, can be used for effectively and smoothly reducing the blood pressure of a patient in prehypertension (120-139 / 80-89mmHg) and with mild hypertension to improve the vasodilatation function of the patient, and does not have remarkable adverse response. The medicinal composition is particularly suitable for a patient in prehypertension, as well as a patient with confirmed primary hypertension.

The invention discloses a method for accurately evaluating blood pressure measurement results of mercury columns of 7-17-year-old children and teenagers in China. The method is based on a complex nonlinear SBP and DBP distribution curve constructed based on a reference population. The method is based on three distribution parameters of the curve in different genders, ages and height percentiles: amedian [mu], a variable coefficient sigma and a skewness Box-Cox conversion power skewness coefficient v required by data conversion normality, and also gives consideration to the skewness and kurtosis coefficients tau of the data; in combination with individual blood pressure measurement values and individual age, gender and height information, the blood pressure percentage digit is accurately calculated on the basis of an equation, and the accurate evaluation is carried out according to the international unified judgment standard '2004 4th children and adolescent hypertension diagnosis, evaluation and treatment guidelines' and the standard of whether hypertension reaches the prehypertension or hypertension or not.

The invention discloses application of streptomyces aureus Tu117 as a marker for detecting and diagnosing hypertension to preparation of a corresponding detection tool. A detection object of the detection tool is excrement, intestinal tissues or intestinal contents collected from a subject. The streptomyces aureus Tu117 of the invention is relatively high in content in bodies of hypertension model mice and hypertension patients, can be used for establishing a detection method or preparing a detection and diagnosis kit, and is used for auxiliary diagnosis and risk assessment of hypertension and prehypertension.

The invention discloses a first-aid cold compressing device for patients with hypertensive cerebral hemorrhage. The first-aid cold compressing device includes a bottom pillow, a top pillow, a hook and loop fastener and a twisting fastener, wherein the bottom pillow and the top pillow are connected by the twisting fastener; the hook and loop fastener includes a lopper fastener and a hook fastener; the twisting fastener includes a limiting buckle and a crossbar; the bottom pillow includes a neck mat, a head mat and a water inlet; the neck mat and the head mat are connected to form a bottom pillow body; the top pillow includes a head ring, a beck ring and a water inlet; the head ring and the neck ring are connected to form a top pillow body. According to the first-aid cold compressing device for patients with hypertensive cerebral hemorrhage, the radian of the bottom pillow designed according to the human engineering can well accord with the body of the patient, the head part cooling speed is improved while the sense comfort of the patient is also considered, and the design is more humanized; the neck ring of the top pillow is fit with the carotid artery, thus playing a role in reducing blood temperature, allowing the cooling of the brain to be more comprehensive, and being more conductive to the therapy of the patient; the first-aid cold compressing device is more safer and flexible due to the arrangement of the twisting fastener.

A computer system and method is disclosed as a support structure for patients with hypertension or prehypertension to encourage life style changes leading to dietary control, increase exercise and blood pressure control. The method includes automated messages and responses delivered in real time to encourage appropriate actions by the patient. A diary feature is provided for user input of various relevant parameters, such as foods consumed, exercise activities, body weight, blood pressure, and heart rate. The computer system and method may be implemented on a mobile computing device, such as a smart phone or wearable, a conventional personal computer, or a web service. Most functions will be provided on the mobile device, but some housekeeping and data visualization functions may be limited to the personal computer or web service implementations.

The present invention provides methods for treating arterial hypertension in a patient. The method includes selecting a patient with arterial hypertension and creating a flow pathway between a first vascular location and a second vascular location. The first vascular location includes a source of arterial blood, and the second vascular location includes a source of venous blood. The method results in a reduction in diastolic blood pressure and a reduction in systolic blood pressure; the reduction in diastolic blood pressure is at least close to the reduction in systolic blood pressure. The present invention also provides systems and devices for creating flow paths.

The invention relates to an application of microRNA (ribonucleic acid) has-miR574-3p in hypertension diagnosis. The application has the advantages as follows: plasma of hypertension patients in prehypertension and normal people is collected for research on whole-genome miR expression profile, research results show that a series of miRs are related to prehypertension and hypertension, and differentially expressed miRs help to explain the molecular mechanism for hypertension incidence; a molecular marker is provided for progress evaluation of prehypertension and hypertension; a brand new therapeutic target is provided for effective blood pressure control and treatment of prehypertension and hypertension; and meanwhile, an antagonist and a mimic containing a single miR or combining multiple miRs are adopted, and a brand new means is provided for treatment of prehypertension and hypertension.

The invention discloses a human body blood pressure limiter which comprises a valve body and a valve core which are arranged in a human body; the area of the front end of the valve core is A; a spring with the elastic force of F is arranged between the upper end of the valve core and that of a valve cavity; a blood inlet is formed on one side of the valve cavity, the inner port of the blood inlet is communicated with the valve cavity, and the outer port is communicated with arterial vessels of the human body through artificial blood vessels; a valve-in pipeline is arranged at the blood inlet and is communicated with the bottom of the valve cavity; a blood outlet is formed on the other side of the valve cavity and is led out of the human body or is communicated with the vein vessels of the human body through the artificial blood vessels; the dangerous critical blood pressure of the human body is set as P; A and F meet the condition that F equals to P multiplied by A; when the blood pressure of the human body is higher than P, the valve core moves upwards, a part of blood flows out of the human body or flows into the vein vessels of the human body from the arterial vessels of the human body through the blood inlet and outlet; and when the blood pressure of the human body is lower than P, the valve core moves downwards so as to block the blood inlet and the blood outlet. The human body blood pressure limiter can limit rising of the blood pressure automatically under the emergent situation that the blood pressure of hypertension personnel rises sharply and seriously threatens lives.

The invention discloses application of alpha-lipomycin as a marker for detecting and diagnosing hypertension to prepare a corresponding detection tool. A detection object of the detection tool is a to-be-detected sample collected from a subject. The content of alpha-lipomycin in hypertension model mice and hypertension patients is relatively high, and the alpha-lipomycin can be used for establishing a detection method or preparing a detection and diagnosis kit and can be used for auxiliary diagnosis and risk assessment of hypertension and prehypertension.

The present application provides methods for treating cardiovascular conditions. The methods can include administering a Transient Receptor Potential Vanilloid 1 (TRPV1) receptor agonist to an epidural space. The methods can be used to treat a variety of conditions such as hypertension, prehypertension, mild hypertension, severe hypertension, refractory hypertension, congestive heart failure and myocardial scarring.

The present invention relates to methods of treating subjects suffering from pre-hypertension or hypertension by administering to a subject in need of treatment thereof a therapeutically effective amount of at least one xanthine oxidoreductase inhibiting compound or salt thereof.

In a basal blood pressure measuring method, an examinee presses a basal blood pressure measuring key after the examinee gets out of bed in the morning to start a sphygmomanometer to measure the basal blood pressure A microprocessor in the sphygmomanometer displays the measured basal blood pressure and date on a display screen and saves the measured basal blood pressure into a basal blood pressure buffer of a memory automatically. When the examinee presses a basal blood pressure average key, the microprocessor in the sphygmomanometer computes and processes the basal blood pressure data in the memory and displays the basal blood pressure average of the current week or the past few weeks on the display screen to inform whether or not the examinee is a hypertension patient.

The present application provides methods for treating cardiovascular conditions. The methods can include administering a Transient Receptor Potential Vanilloid 1 (TRPV1) receptor agonist to an epidural space. The methods can be used to treat a variety of conditions such as hypertension, prehypertension, mild hypertension, severe hypertension, refractory hypertension, congestive heart failure and myocardial scarring.

The invention discloses an application of stervioside in the preparation of a therapeutic drug and a health product for prehypertension. Through experimental tests of dietary supplement of stevioside to spontaneously hypertensive rats with blood pressure not elevated yet, it is found that stevioside has an effect of delaying elevation of arterial blood pressure for prehypertension. Stevioside can lower JAK2 / STAT3 and SOCS3 expression, improve vascular insulin resistance and delay elevation of blood pressure. It shows that stevioside can improve resistance vessel functions by inhibiting vascular insulin resistance and delay elevation of blood pressure. Thus, stevioside can be used in preparation of a therapeutic drug and a health product for prehypertension, has a good research and application prospect, and provides a new control strategy and experimental evidence for early effective intervention with prehypertension people so as to prevent generation and development of clinical hypertension.