The art paint box for art design comprises a paint box body and a top cover, the top cover is installed at the top of the paint box body, a sealing ring is arranged at the bottom of the top cover, a sealing groove is formed in the top of the paint box body, the sealing ring is embedded in the sealing groove, a positioning plate is arranged in the paint box body, and the positioning plate is arranged in the paint box body. A fixing frame is arranged in the paint box body. According to the art paint box for art design, the positioning plate, the positioning groove, the fixing frame and other structures are installed in the paint box body, so that the paint box body is convenient to clean, when the paint box needs to be cleaned, the top cover is taken out from the top of the paint box body firstly, then the fixing frame and paint are taken out, and the paint box is convenient to clean. In this way, the positioning groove in the bottom of the fixing frame can be taken out of the positioning plate, a user can clean the interior of the paint box body, and operation is easy during cleaning.