Avian coccidiosis vaccine stabilizer for spray or water drinking immunization, and preparation method and application thereof

Abstract

The invention provides an avian coccidiosis vaccine stabilizer for spray or water drinking immunization, and a preparation method and an application thereof. The stabilizer mainly comprises 10-35% ofedible gum, 2-5% of sodium alginate, 3-12% of a water stable compound sodium polyacrylate, 0.1-0.5% of a food coloring, 0.1-0.5% of a sweetener, 2-8% of ginseng leaf extract and 39-82.8% of dextrin. The prepared stabilizer is suitable for being diluted during water drinking immunization or spray immunization with an avian coccidiosis vaccine, can make the chicken coccidian oocysts form a uniformlydispersed system in water and keep for 8 h or more without settling, and improves the avian coccidiosis immunization effect.

Description

technical field [0001] The invention relates to a chicken coccidia vaccine stabilizer for spraying or drinking water and its preparation method and application. Background technique [0002] Chicken coccidiosis is the most susceptible to the disease for chicks over 10 days old, and its incidence rate can be as high as 50% to 70%, the fatality rate is usually 20% to 30%, and severe cases can be as high as 80%. cause serious economic losses. At present, it is mainly based on the use of anticoccidial drugs in the feed for prevention, or the use of anticoccidial drugs for treatment after the clinical symptoms of coccidiosis infection appear. As far as the current situation is concerned, the use of anticoccidial drugs cannot completely control chicken coccidiosis happened. Later, it developed into the use of chicken coccidiosis live vaccine for oral immunization to prevent chicken coccidiosis. Chicken coccidiosis vaccine is mainly immunized by feed or drinking water, and has ac...

AI Technical Summary

Problems solved by technology

However, in the promotion and application of chicken coccidia vaccines, a series of problems affecting the immune effect have been encountered. One is that the activity of chicken coccidia oocysts will weaken or die in a dry environment, resulting in poor immune effects. Improper methods in the preservation process can easily lead to immune failure; the second is that chicken coccidia oocysts have a large proportion and are prone to precipitation in water. Chickens cannot be evenly immunized or some chickens ingest excessive coccidiosis oocysts and chicken coccidiosis breaks out. At present, chicken coccidia oocysts are also added to the suspending agent to suspend the coccidia oocysts in the water system in a short period of time, but the operation is time-consuming and laborious, and it cannot be drunk for a long time, and the promotion is limited to a certain extent. In some cases, the chicken coccidia oocysts are still sprayed on the surface of the feed for mixing immunity

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