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Hemostasis and healing promotion waterless gel with biological glass micro balls for cervix uteri wound repairing

A bioglass and wound repair technology, which is applied in the field of improvement of medical wound repair gel, can solve the problems of wounds, difficult to heal wounds, poor hemostatic effect, etc., and achieve the effect of rapid hemostasis, reducing exudation, reducing bleeding, and promoting wound healing.

Inactive Publication Date: 2018-02-23
张家港蓝智生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are many ways and means of hemostasis and repair of medical wounds and wounds, including various physical methods, chemical methods, hydrogels, etc. These methods have their own advantages and disadvantages. Some of them have poor hemostatic effect, and some ingredients contain water. Can cause wounds and wounds to be difficult to heal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The technical scheme adopted in this embodiment is: it is prepared with poloxamer or carbomer as the gel matrix material, microporous bioactive glass and chitosan as the main functional components, and the parts by weight of its raw material formula As follows: carbomer: 1 part, microporous bioactive glass: 3 parts, medical glycerin: 35.5 parts, propylene glycol: 25.5 parts, chitosan: 0.8 parts, sodium hyaluronate: 0.2 parts.

[0018] Described carbomer selects carbomer 940 for use.

[0019] The present invention reduces bleeding, has long-term bacteriostasis, and promotes wound healing through the adsorption of microporous biological glass and the hemostatic and healing-promoting functions of the bioactive glass and chitosan. It is a functional medical device product with broad application prospects. Its main features:

[0020] 1. Hemostatic effect: through nano-scale micropores and chitosan powder, it can quickly absorb blood and quickly reduce bleeding; 2. Neutrali...

Embodiment 2

[0023] The technical scheme adopted in this embodiment is: it is prepared with poloxamer or carbomer as the gel matrix material, microporous bioactive glass and chitosan as the main functional components, and the parts by weight of its raw material formula As follows: carbomer: 1.5 parts, microporous bioactive glass: 10 parts, medical glycerin: 45 parts, propylene glycol: 40 parts, chitosan: 1.5 parts, sodium hyaluronate: 0.6 parts.

Embodiment 3

[0025] The technical scheme adopted in this embodiment is: it is prepared with poloxamer or carbomer as the gel matrix material, microporous bioactive glass and chitosan as the main functional components, and the parts by weight of its raw material formula As follows: carbomer: 2 parts, microporous bioactive glass: 20 parts, medical glycerin: 65.5 parts, propylene glycol: 55.5 parts, chitosan: 2.0 parts, sodium hyaluronate: 1.0 parts.

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PUM

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Abstract

The invention relates to a hemostasis and healing promotion waterless gel with biological glass micro balls for cervix uteri wound repairing and relates to improvement of a medical wound repairing gel, in particular to the hemostasis and healing promotion waterless gel with biological glass micro balls for cervix uteri wound repairing. The gel is prepared in the mode that poloxamer or carbomer isused as a gel matrix material and micro-hole bioactive glass and chitosan are used as main functional components. The raw material composition of the gel comprises, by weight, 1-2 parts of carbomer, 3-20 parts of micro-hole bioactive glass, 35.5-65.5 parts of medical glycerinum, 25.5-55.5 parts of propanediol, 0.8-2.0 parts of chitosan and 0.2-1.0 part of sodium hyaluronate. According to the hemostasis and healing promotion waterless gel, through the adsorption effect of the micro-hole bioactive glass and the hemostasis and healing promotion functions of the micro-hole bioactive glass and thechitosan, hemorrhage is reduced, bacteria are effectively inhibited for a long time, and wound healing is promoted. The gel is a functional medical instrument product with wide application prospects.

Description

technical field [0001] The invention relates to an improvement of a medical wound repairing gel, in particular to an anhydrous gel containing biological glass microspheres for hemostasis and promoting healing of cervical wound repair. Background technique [0002] Microporous glass is a kind of granular porous glass with good rigidity and high mechanical strength. It is mainly used in the production of high-silica glass and is used in bioengineering, genetic engineering, refining of biology and pharmaceuticals, and immobilizing enzymes. [0003] Due to its unique composition, structure and characteristics, microporous glass has been developed into a new functional material with many uses. In medicine, it can be used as a separation membrane for medical purposes such as blood purification. [0004] Hydrogels are gels in which water is the dispersion medium. A part of hydrophobic groups and hydrophilic residues are introduced into the water-soluble polymer with a network cro...

Claims

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Application Information

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IPC IPC(8): A61L24/08A61L24/02A61L24/06A61L24/00
CPCA61L24/0015A61L24/0031A61L24/02A61L24/06A61L24/08A61L2300/10A61L2300/236A61L2300/404A61L2300/41A61L2300/412A61L2400/04C08L5/08C08L33/02
Inventor 张劲松朱礼飞李保芝张宇辰
Owner 张家港蓝智生物科技有限公司
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