Production method of ''W'' model of sharp biological membrane for improving fracture healing

Abstract

The present invention provides a "W" model manufacturing method of a pointed biofilm for improving fracture healing. 2) Wet elastic layer and drug layer are respectively made, the elastic layer is a dense degradable or non-degradable biofilm, and the material of the drug layer is degradable or non-degradable with good biocompatibility with human bone, Absorb or not absorb or porous porous substances, and the drug layer is also encapsulated with drugs that promote bone healing; 3) The moist elastic layer is covered on the two raised peaks of the model, wrapping the two models. The raised peaks extend to both sides of the top corner of the model, and then the wet drug layer is covered on the elastic layer to form a biomicrostructure film; 4) After the biomicrostructure film is air-dried and the shape is fixed, the fabricated biomicrostructure The membrane peels off the top corners of the model. 5), cut the "W" type membrane into a "V" type membrane.

Description

technical field [0001] The invention relates to a method for making a "W" model of a pointed biofilm for improving fracture healing. Background technique [0002] At present, it is a frontier field of medical research to use a biocomposite film containing growth factors / stem cells to stick to the fracture line to enhance the speed and quality of fracture healing. There are blood vessels and bone cells distributed on the inner surface of the fracture line (anastomosis line), and whether the healing is good depends on the growth of blood vessels and bone cells in the fracture line. The reason why biofilm sticking to the surface of fracture anastomosis can increase the quality of fracture healing is that on the one hand, the drugs encapsulated in the biofilm can promote the growth of blood vessels and bone cells in the fracture anastomosis, and on the other hand, the biological The membrane isolates external muscles and other human tissues from the fracture anastomotic line, a...

AI Technical Summary

Problems solved by technology

[0004] 1. The biocomposite membrane has a relatively large volume area and a small fracture area, and 2 cannot be effectively fitted and fixed together

[0005] 2. The limitations of the current biocomposite membrane materials and manufacturing process lead to performance indicators such as the degradation rate of the biocomposite membrane and the time for the carried growth factors to release the effective drug concentration (the duration of the effective concentration is the key to the healing quality of the fracture line) Unable to meet clinical needs

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