A kind of lipid-lowering traditional Chinese medicine composition and its preparation method and application

The technology of a composition and a pharmaceutical preparation is applied in the field of lipid-lowering traditional Chinese medicine compositions, and can solve the problems of intolerance, intolerance of liver damage, myolysis, poor lipid-lowering effect and the like

Active Publication Date: 2020-12-11
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although intensive statins can effectively reduce the level of LDL-C, although some patients have used large doses of statins, LDLC still has not reached the normal level, and some patients have liver damage and muscle damage due to intolerance of statins. Therefore, for patients with poor lipid-lowering effect and intolerance of statins, it is particularly important to study new lipid-lowering drugs

Method used

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  • A kind of lipid-lowering traditional Chinese medicine composition and its preparation method and application
  • A kind of lipid-lowering traditional Chinese medicine composition and its preparation method and application
  • A kind of lipid-lowering traditional Chinese medicine composition and its preparation method and application

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1: honey pill

[0028] The raw materials are taken according to the following weight ratio: 2 grams of fried scutellaria baicalensis, 2 grams of raw Puhuang, 2 grams of sealwort, 2 grams of Polygonum cuspidatum, 2 grams of turmeric, and 2 grams of caper fruit.

[0029] The above Qiwei raw materials were pulverized and mixed respectively to make a powdery mixture, and then made into honeyed pills according to the conventional method in this field, each honeyed pill was 3 grams, and was taken orally twice a day, 2 capsules each time.

Embodiment 2

[0030] Embodiment 2: Granules

[0031] The raw materials are taken according to the following weight proportions: 4 grams of fried scutellaria baicalensis, 6 grams of raw Puhuang, 7 grams of sealwort, 4 grams of Polygonum cuspidatum, 4 grams of turmeric, and 7 grams of caper fruit.

[0032] Add water to decoct the above Qiwei raw materials for 2 times, count from boiling, each time for 1 hour, add 10 times the amount of water for the first time, add 8 times the amount of water for the second time, after the decoction is completed, filter through 10 layers of gauze, and combine the two The filtrate is concentrated to an extract with a specific gravity of 1.35, added appropriate amount of dextrin and powdered sugar, dried at 70°C, and made into granules, ready to be prepared, bagged, 10 grams per bag, orally 3 times a day, 1 bag each time.

Embodiment 3

[0033] Embodiment 3: decoction

[0034] The raw materials are taken according to the following weight proportions: 9 grams of fried scutellaria baicalensis, 12 grams of raw Puhuang, 15 grams of sealwort, 9 grams of knotweed, 12 grams of turmeric, and 15 grams of caper fruit.

[0035] The above seven-flavor raw materials are decocted twice with an appropriate amount of water, counted from boiling, and each time is 1 hour. After the decoction is completed, the two decoction liquids are combined. The method of administration is: take twice a day.

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Abstract

The invention discloses a traditional Chinese medicine composition with a function of reducing blood fat. The traditional Chinese medicine composition is mainly prepared from the following effective component raw material medicines in parts by weight: 2-9 parts of fried radix scutellariae, 2-12 parts of raw pollen typhae, 2-15 parts of rhizoma polygonati, 2-9 parts of rhizoma polygoni cuspidati, 2-12 parts of radix curcumae and 2-15 parts of capparis spinosa fruit. The invention also discloses application of the traditional Chinese medicine composition in preparation of drugs for reducing blood fat. The invention also provides a pharmaceutical preparation prepared from the traditional Chinese medicine composition and pharmaceutical adjuncts. The traditional Chinese medicine composition provided by the invention has a remarkable blood fat reducing effect, is more obvious in effect compared with all the single medicines, and has a synergistic effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a lipid-lowering traditional Chinese medicine composition, a preparation method of the compound and an application in the fields of food, health products or traditional Chinese medicine. Background technique [0002] Dyslipidemia usually refers to elevated plasma triglycerides (triglyceide, TG) and (or) total cholesterol (total cholesterol, TC), commonly known as hyperlipidemia. In fact, hyperlipidemia also generally refers to various blood lipid abnormalities including low-density lipoprotein (lowdensity lipoprotein, LDL) hyperlipidemia. Although the blood lipid level and the prevalence of dyslipidemia in the Chinese population are still lower than those in most western countries, with the development of society and economy, the improvement of people's living standards and the change of lifestyle, the average serum TC level of the population is gradually increasing. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P3/06
CPCA61K9/0056A61K36/185A61K36/539A61K36/704A61K36/88A61K36/8969A61K36/9066A61K2300/00
Inventor 周华杨涛杨雪军瞿惠燕
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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