The invention provides health wine capable of enabling old people to glow and live well and long. The health wine is prepared from the following components: astragalus membranaceus, angelica sinensis, radix pseudostellariae, schisandra chinensis, fructus rosae laevigatae, the fruits of Chinese wolfberry, caltrop, pilose antler, tortoise shell, the root of red-rooted salvia,ligusticum wallichii, semen sesami nigrum, nut, prepared polygonum multiflorum, dandelion, radix angelicae pubescentis, lycopodium clavatum, sea-buckthorn, morinda officinalis, desertliving distance, Armstrong, fringed pink, coix seeds, liquorice, eucommia ulmoides, rhizoma cyperi, flatstem milkvetch seeds, semen plantaginis, mulberries, longan aril, raw hawthorn fruits and parasitic loranthus. The health wine is prepared from the following steps: grinding all the raw materials, packing into a hop-pocket, placing the hop-pocket into white spirit of 70 degrees or above and heated to 50-60 DEG C, soaking, carrying out cave storage for one month, and blending the brewed wine to be 39 degrees, and thus obtaining the health wine. The medicated wine can directly reach the viscera of the old people, so that the functions of the organs are balanced, and the mutual nourishing and complementary tonifying can delay pro-senescence of cells, and repair the cells lost due to no in-advance maintenance, so that the efficacies of recovering the cell viability, eliminating in-vivo free radicals, and regrowing immune system factors and growth factors are achieved, and thus the cell function is activated, and the life is prolonged.