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Extract for treating pelvic inflammation and preparation method thereof

An extract and a technology for pelvic inflammatory disease, which are applied in the field of extracts for the treatment of pelvic inflammatory disease and their preparation, can solve the problems of affecting the curative effect, infection, and low effective content, so as to reduce the inflammatory response and pathological changes, and reduce the level of IL-6. level, the effect of reducing MDA levels

Active Publication Date: 2018-08-03
ANHUI JINGFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 2. Infection after intrauterine surgery
[0007] Such as placement or removal of intrauterine contraceptive ring, curettage, tubal fluid, hysterosalpingography, hysteroscopy, submucosal myomectomy, etc., due to preoperative sex life or surgical disinfection is not strict or preoperative Improper selection of indications can lead to the onset and spread of acute infection after surgery; some patients do not pay attention to personal hygiene after surgery, or do not follow the doctor's advice after surgery, which can also cause bacterial infection and cause pelvic inflammatory disease
[0008] 3. Poor menstrual hygiene
[0016] However, this product and other similar products on the market have the disadvantages that the active ingredients cannot be fully extracted and utilized, the effective content is low, there are many impurities, the dosage is large, and the curative effect is affected. , taking small doses of Chinese patent medicine preparations has attracted more and more attention, and has broad market prospects

Method used

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  • Extract for treating pelvic inflammation and preparation method thereof
  • Extract for treating pelvic inflammation and preparation method thereof
  • Extract for treating pelvic inflammation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Example 1: Granules

[0069] 1. Medicine composition: Diren 800g, liangmianzhen 240g, angelica 200g, five-finger hair peach 160g, piercing stone 200g.

[0070] 2. Preparation method:

[0071] 1) Weigh clean Diren medicinal materials, add 10 times the amount of water, heat to 90℃ and extract 3 times for 2 hours each time, filter, and concentrate the filtrate to a relative density of 1.25 when the temperature is 60℃. Cool, add 50% ethanol , Stand for 24 hours, filter, the filtrate recovers ethanol, concentrates to a thick paste, dried, pulverized into fine powder for use.

[0072] 2) Take LMZ medicinal materials, add 10 times the amount of water, heat to 90°C and extract 3 times, 2 hours each time, filter, concentrate the filtrate to a temperature of 65°C with a relative density of 1.20, cool, add 55% ethanol, and let stand After 24 hours, filter and recover ethanol from the filtrate, concentrate to thick paste, dry, pulverize into fine powder, and set aside.

[0073] 3) Take the...

Embodiment 2

[0086] Example 2: Capsules

[0087] 1. Medicine composition: Diren 750g, liangmianzhen 250g, angelica 100g, five-finger hair peach 80g, and piercing stone 100g.

[0088] 2. Preparation method:

[0089] 1) Weigh clean Diren medicinal materials, add 10 times the amount of water, heat to 90℃ and extract 3 times for 2 hours each time, filter, and concentrate the filtrate to a relative density of 1.25 when the temperature is 60℃. Cool, add 50% ethanol , Stand for 24 hours, filter, the filtrate recovers ethanol, concentrates to a thick paste, dried, pulverized into fine powder for use.

[0090] 2) Take LMZ medicinal materials, add 10 times the amount of water, heat to 90°C and extract 3 times, 2 hours each time, filter, concentrate the filtrate to a temperature of 65°C with a relative density of 1.20, cool, add 55% ethanol, and let stand After 24 hours, filter and recover ethanol from the filtrate, concentrate to thick paste, dry, pulverize into fine powder, and set aside.

[0091] 3) Take ...

Embodiment 3

[0100] Example 3: Tablet

[0101] 1. Medicine composition: Diren 1000g, liangmianzhen 300g, angelica 260g, five-finger hair peach 200g, piercing stone 260g.

[0102] 2. Preparation method:

[0103] 1) Weigh clean Diren medicinal materials, add 10 times the amount of water, heat to 90℃ and extract 3 times for 2 hours each time, filter, and concentrate the filtrate to a relative density of 1.25 when the temperature is 60℃. Cool, add 50% ethanol , Stand for 24 hours, filter, the filtrate recovers ethanol, concentrates to a thick paste, dried, pulverized into fine powder for use.

[0104] 2) Take LMZ medicinal materials, add 10 times the amount of water, heat to 90°C and extract 3 times, 2 hours each time, filter, concentrate the filtrate to a temperature of 65°C with a relative density of 1.20, cool, add 55% ethanol, and let stand After 24 hours, filter and recover ethanol from the filtrate, concentrate to thick paste, dry, pulverize into fine powder, and set aside.

[0105] 3) Take the ...

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Abstract

The invention relates to an extract for treating pelvic inflammation as well as a preparation method and application thereof. The extract is prepared from the following traditional Chinese medical materials in parts by weight: 600 to 1000 parts of herba melastomatis dodecandri, 180 to 300 parts of radix zanthoxyli, 150 to 260 parts of radix angelicae sinensis, 120 to 200 parts of radix fici simplicissimae and 150 to 230 parts of root of cudrania tricuspidata Bun. The active ingredients are herba melastomatis dodecandri alcohol water extracts, radix zanthoxyli alcohol water extracts, radix angelicae sinensis alcohol water extracts, radix fici simplicissimae alcohol water extracts, root of cudrania tricuspidata Bun alcohol water extracts. The extract is prepared through the methods of waterextraction, ethanol extraction and the like. The extract has the advantages of high active ingredient content, small medicine taking dose and no toxic and side effects; the exact curative effect is achieved in aspects of treating common gynecological diseases such as acute and chronic pelvic inflammation.

Description

Technical field: [0001] The invention relates to the field of medical inventions, in particular to an extract for treating pelvic inflammation and a preparation method thereof. Background technique [0002] Pelvic inflammatory disease refers to inflammation of female reproductive organs, connective tissue around the uterus, and pelvic peritoneum. The clinical manifestations are acute pelvic inflammatory disease and chronic pelvic inflammatory disease. Chronic pelvic inflammation often results from incomplete treatment in the acute phase, and its onset time is long and the condition is more stubborn. Bacteria are infected retrogradely and reach the pelvic cavity through the uterus and fallopian tubes. But in real life, not all women will suffer from pelvic inflammatory disease, and only a small number of them. This is because the female reproductive system has a natural defense function. Under normal circumstances, it can resist the invasion of bacteria. Only when the body's re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61P15/00
CPCA61K36/185A61K36/232A61K36/60A61K36/758A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61P15/00A61K2300/00
Inventor 高武左言东王宗保王琳聂飞龙熊寅攀陈月红吕迎四陈守清肖传凤胡文高王元生
Owner ANHUI JINGFANG PHARMA
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