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Peptide-containing composition and stabilizer, stabilizing method, and storage method for peptide

A composition and stabilizer technology, applied in the directions of botanical equipment and methods, chemicals for biological control, drug combinations, etc., can solve the problems of reduced glutathione quality, reduced quality, unpleasantness, etc.

Active Publication Date: 2018-09-28
KANEKA CORP
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] On the other hand, it is described in Patent Document 2 that glutathione (GSH or GSSG) has the property of deteriorating in quality due to the influence of heat, oxygen, light, etc., and as a result, an unpleasant odor such as sulfur may be generated, The content in the preparation is reduced, and the quality of glutathione is significantly reduced when glutathione and arginine coexist

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  • Peptide-containing composition and stabilizer, stabilizing method, and storage method for peptide
  • Peptide-containing composition and stabilizer, stabilizing method, and storage method for peptide
  • Peptide-containing composition and stabilizer, stabilizing method, and storage method for peptide

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Embodiment

[0116]Hereinafter, the present invention will be described with reference to specific examples. However, the following specific examples do not limit the scope of the present invention. In addition, GSSG used in each test does not contain GSH (reduced glutathione).

[0117]

[0118] GSSG-containing pellets of the compositions shown in the table below were produced by extrusion granulation, and the storage stability of GSSG was confirmed.

[0119]

[0120] A leftward arrow in Table 1 indicates that the value of each column including it is the same as that of the column on the left. That is, in Comparative Examples 2 to 4 and Examples 1 to 8, the value of each column containing the leftward arrow in Table 1 is the same as that of Comparative Example 1. Specifically, in Comparative Examples 2 to 4 and Examples 1 to 8 8, GSSG NH 3 Both are 2.3% by mass, potassium sulfate is both 11.0% by mass, surfactant is both 3.0% by mass, PVA is both 2.0% by mass, and CMC Na is both 2....

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Abstract

The present invention provides novel technology for improving the storage stability of peptides such as glutathione. The present invention relates to a peptide-containing composition that comprises apeptide and an alkaline mineral carrier and in which there are 8 parts by mass of more of the alkaline mineral carrier with respect to 100 parts by mass of the peptide. The present invention also relates to a plant cultivation method that includes applying the peptide-containing composition to a plant. The present invention also relates to a stabilizer for a peptide, said stabilizer containing thealkaline mineral carrier. The present invention also relates to a method for improving the stability of a peptide, said method including a mixing step in which the alkaline mineral carrier is mixed with the peptide. The present invention also relates to a method for storing a peptide, said method including a storage step in which the peptide is stored together with the alkaline mineral carrier.

Description

technical field [0001] The present invention relates to compositions containing peptides. In addition, the present invention relates to stabilizers for stabilizing peptides. The invention also relates to methods of stabilizing peptides. The invention also relates to methods of preserving peptides. Background technique [0002] Glutathione is a peptide composed of three amino acids, L-cysteine, L-glutamic acid, and glycine. It exists not only in the human body, but also in other animals, plants, microorganisms, and other organisms. Active oxygen elimination, detoxification, amino acid metabolism, etc. are important compounds for living organisms. [0003] Glutathione exists in the body as reduced glutathione (N-(N-γ-L-glutamyl-L-cysteinyl) glycine, hereinafter sometimes referred to as "GSH") and oxidized glutathione Glutathione (hereinafter sometimes referred to as "GSSG") exists in either form, the reduced glutathione is the SH form in which the thiol group of the L-cyst...

Claims

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Application Information

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IPC IPC(8): C07K5/093A01N25/08A01N41/12A01P21/00A01N61/00
CPCA01N41/12C05D9/00A61P39/06A01N25/08C05F11/10
Inventor 渡边豊辉浅田隆之上北健
Owner KANEKA CORP
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