Drug interaction modeling and risk evaluation method, terminal equipment and storage medium

A technology of risk assessment and risk assessment model, applied in drug interaction modeling and risk assessment methods, terminal equipment and storage media fields, can solve problems such as low flexibility, secondary injury to patients, restrictions, etc., to reduce adverse drug reactions , the effect of reducing the incidence and ensuring the safety of medication

Active Publication Date: 2018-10-09
XIAMEN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On the one hand, this traditional method consumes a lot of manpower and material resources, and it is difficult to completely cover all the drug combination information based on the judgment method based on literature materials. On the other hand, this method has low flexibility. When using drug combinations or using new drugs, the system cannot give correct drug interaction information and pharmacists do not

Method used

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  • Drug interaction modeling and risk evaluation method, terminal equipment and storage medium
  • Drug interaction modeling and risk evaluation method, terminal equipment and storage medium
  • Drug interaction modeling and risk evaluation method, terminal equipment and storage medium

Examples

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Embodiment 1

[0045] refer to figure 1 and figure 2 As shown, the present invention provides a drug interaction modeling and risk assessment method, comprising the following steps:

[0046] S100: extract the drug combination records from the electronic medical record database, obtain the drug combination list, and construct a drug interaction risk assessment model according to the drug combination conditions in the drug combination list.

[0047] The electronic medical record database can be obtained through the hospital information system of a medical institution, etc. In this embodiment, the outpatient electronic medical record database of a tertiary hospital in 2015 was used for one year, and the data in the database were denoised and cleaned to obtain About 3 million valid electronic medical records, from which combined medication records are extracted to obtain a list of drug combinations.

[0048] S100 specifically includes the following steps:

[0049] S110: Extract the drug comb...

Embodiment 2

[0090] The present invention also provides a drug interaction modeling and risk assessment terminal device, including a memory, a processor, and a computer program stored in the memory and operable on the processor, and the processor executes the computer program. The program realizes the steps in the above-mentioned method embodiment of Embodiment 1 of the present invention.

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Abstract

The invention relates to a drug interaction modeling and risk evaluation method, terminal equipment and a storage medium. The method comprises steps that S100, a drug combination list from an electronic medical record database is obtained, and a drug interaction risk evaluation model is constructed according to the drug combination status therein; S200, to-be-inquired drug names are inputted in the drug interaction risk evaluation model, if the drug interaction risk evaluation model already has the drug combination status information of the to-be-inquired drug group, the corresponding drug interaction risk evaluation information is outputted; S300, if not, the component information of drugs in the drug group is utilized to construct a drug similarity matrix, in combination with the drug similarity matrix and the drug interaction risk evaluation model, the corresponding drug interaction risk evaluation information is outputted. The method is advantaged in that the drug interaction riskevaluation information is outputted through the drug interaction risk evaluation model, and accurate and effective decision basis is provided for reasonable clinic drug combination.

Description

technical field [0001] The invention relates to the field of clinical pharmaceutical affairs management, in particular to a drug interaction modeling and risk assessment method, a terminal device and a storage medium. Background technique [0002] Drug Interaction (Drug Interaction) refers to the drug effect changes that occur when two or more drugs are used at the same time. That is to produce synergistic (synergistic), additive (increase), and antagonistic (reduction) effects. Reasonable drug interactions can enhance the curative effect or reduce adverse drug reactions, otherwise it can lead to reduced curative effect or increased toxicity, and some abnormal reactions may also occur, interfere with treatment, and aggravate the condition. [0003] The causes of diseases are generally more complex, and there is almost no possibility of a single factor causing the disease, and each drug has its corresponding applicable symptoms and curative effects, so combination therapy is...

Claims

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Application Information

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IPC IPC(8): G16H70/40G16H50/70
CPCG16H50/70G16H70/40
Inventor 邵云婷陈龙彪洪灵鸿王珏吴妙莲范晓亮陈坚王程李军
Owner XIAMEN UNIV
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