Preparation method of nanomaterial for preventing decayed teeth and treating superficial caries

A nano-material and dental caries prevention technology, applied in the field of nano-biotechnology and oral care, can solve the problems that antibiotics do not have broad-spectrum antibacterial ability, poor bacterial inhibition effect, and endanger public drug safety, so as to protect the surface structure of teeth, Inhibition of adhesion and proliferation, excellent broad-spectrum antibacterial ability
CN109010089AActive Publication Date: 2018-12-18合肥诺创新材料科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
合肥诺创新材料科技有限公司
Publication Date
2018-12-18

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Abstract

The invention discloses a preparation method of a nanomaterial for preventing decayed teeth and treating superficial caries, and relates to the fields of nano-biotechnologies and oral care technologies. The preparation method comprises the following steps: uniformly dispersing polydopamine particles in an aqueous solution system, adding an aqueous solution containing silver ions under a magnetic stirring condition, carrying out a reaction for a period of time, performing high-speed centrifuging, discarding the obtained supernatant, and washing the obtained reaction product with deionized water; and slowly adding an aqueous solution of molecules having the ability to recognize dental enamel to a high-speed stirred catalyst system solution, carrying out a reaction for a period of time, slowly adding the prepared antibacterial component-immobilized core aqueous solution to the obtained high-speed stirred solution system, carrying out a reaction for a period of time, performing high-speedcentrifugation, discarding the obtained supernatant, washing the obtained reaction product with deionized water to obtain the nanomaterial. The nanomaterial prepared by the preparation method is formed by the inner nanoparticle core having an induced mineralization effect, and an external containing the above broad-spectrum antibacterial component and the dental enamel recognition molecules.
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Description

technical field

[0001] The invention belongs to the technical fields of nano-biotechnology and oral care, and in particular relates to a preparation method of a nano-material used for caries prevention and shallow caries treatment. Background technique

[0002] Caries is a common and frequently-occurring disease in humans, and its incidence rate remains high. The results of the third national oral health epidemiological survey show that the caries rate of deciduous teeth of 5-year-old children is as high as 66%, and the prevalence rate of permanent teeth of 12-year-old children is 28.9%, and the prevalence rate of caries among people over 35 years old is even higher 88%, and the prevalence gradually increased with age. This disease not only directly affects the healthy growth of children and adolescents, but also affects the quality of life of adults, so it is extremely urgent to find more effective and simple methods of caries prevention and treatment.

[0003] Dental car...

Claims

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