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128results about How to "Good broad-spectrum antibacterial effect" patented technology

Antibacterial and breathable home textile fabric and making method thereof

The invention provides an antibacterial and breathable home textile fabric and a preparation method thereof. The home textile fabric comprises an antibacterial surface layer, an antibacterial particleintermediate layer, a protective intermediate layer and an antibacterial bottom layer arranged from top to bottom in sequence, wherein the antibacterial surface layer and the antibacterial bottom layer are braided from antibacterial polyester fibers and cotton fibers; the protective intermediate layer is braided from milk protein fibers and cotton fibers; the antibacterial particle intermediate layer comprises a vertically arranged aramid fiber support and antibacterial nano-silver particles; the antibacterial particle intermediate layer is partitioned into multiple cavities by the aramid fiber support; the antibacterial nano-silver particles are distributed in the cavities; and the antibacterial nano-silver particles are prepared by soaking polyamide filaments with antibacterial nano-silver liquid and cutting. According to the antibacterial and breathable home textile fabric and the preparation method thereof provided by the invention, the cost for preparing the antibacterial and breathable fabric is reduced, the antibacterial and breathable properties are improved, and direct contact between the antibacterial nano-silver particles and human skin can be avoided.
Owner:绍兴韩优针纺织有限公司

Antibacterial peptide and pharmaceutical composition and application thereof

The present invention provides an antibacterial peptide, and a pharmaceutical composition and applications thereof. The antibacterial peptide comprises any one of an antibacterial peptide 1, an antibacterial peptide 2 and an antibacterial peptide 3, the amino acid sequence of the antibacterial peptide 1 is represented by SEQ ID No: 1, the amino acid sequence of the antibacterial peptide 2 is represented by SEQ ID No: 2, and the amino acid sequence of the antibacterial peptide 3 is represented by SEQ ID No: 3. The three antibacterial peptides are formed by modifying natural antibacterial peptides PGLa-AM1 as the basis, and have the characteristics of stronger antibacterial effect and better performance. The inhibitory effect of the three antibacterial peptides on helicobacter pylori is stronger than that of PGLa-AM1, the broad-spectrum antibacterial effect of the antibacterial peptide 3 is the strongest, and the antibacterial peptide 3 has good pH responsiveness, so that the antibacterial peptide 3 is in better contact with helicobacter pylori and inhibits growth of helicobacter pylori. The three antibacterial peptides have advantages of strong antibacterial activity, strong biocompatibility and low cost, and are expected to be widely used.
Owner:SHANGHAI INST OF APPLIED PHYSICS - CHINESE ACAD OF SCI

Nanometer silver/berberine slow release coating loaded calcium phosphate ceramic material and preparation method

The invention discloses a nanometer silver / berberine slow release coating loaded calcium phosphate ceramic material and a preparation method. The nanometer silver / berberine slow release coating loadedcalcium phosphate ceramic material consists of calcium phosphate ceramics and nanometer silver / berberine composite slow release coating loaded on the surface of the calcium phosphate ceramics. The calcium phosphate ceramics are prepared through sintering calcium phosphate ceramic raw material powder, nanometer silver is prepared through in-situ reduction of silver nitrate through silk fibroin, berberine molecules are mixed, nanometer silver / berberine mixed liquor is obtained and is connected to the surface of the calcium phosphate ceramics through polydopamine, and the nanometer silver / berberine slow release coating loaded calcium phosphate ceramic material is prepared. According to the nanometer silver / berberine slow release coating loaded calcium phosphate ceramic material and the preparation method disclosed by the invention, berberine and antibacterial effects of nanometer silver granules are combined, so that the potential effects of the berberine for promoting osteogenic differentiation of cells can be sufficiently exerted. The berberine and the nanometer silver have the effect of cooperating for resisting bacteria, so that the concentration of the nanometer silver is reduced, and reduction of cytotoxicity of implantation materials is facilitated. The composite material can be applied to bone defect repair and oral cavity implants.
Owner:SICHUAN UNIV

Nanoparticle-embedded amyloid protein fiber filter membrane and method used for pollutant degradation

The invention relates to a nanoparticle-embedded amyloid protein fiber filter membrane and a method used for pollutant degradation. A filter membrane with catalytic activity is prepared by utilization of amyloid protein fibers coating nanoparticles and used for catalysis degradation of pollutants. The method concretely comprises steps: a nanoparticle-amyloid protein fiber composite material is prepared; a composite filter membrane is prepared from the composite material; the composite filter membrane is applied in degradation of corresponding pollutants, and the membrane catalytic reaction conversion rate is adjusted through control of a flow velocity of a pollutant solution. When the catalytic reaction is compared with a catalytic reaction employing nanoparticles, the nanoparticles are embedded in the amyloid protein fibers, loss of the nanoparticles is prevented, the filter membrane can be used repeatedly after preparation film forming, and the economic cost is lowered. The composite filter membrane preparation and the method used for pollutant degradation is advantageous in that preparation conditions are mild and simple, the catalysts can be utilized repeatedly, and degradation operation is fast and convenient.
Owner:TIANJIN UNIV

Method for producing recombinant sea cucumber antalzyme and recombinant sea cucumber antalzyme produced thereby

The invention relates to a production method for recombinant holothurian lysozyme and the recombinant holothurian lysozyme produced by the method. The method comprises the following steps: collecting a holothurian lysozyme gene (SEQ ID NO.1) to a eukaryotic expression vector pPIC9K to construct recombinant plasmid, transforming the formed recombinant plasmid into Pichia pastoris SMD 1168, inducing the recombinant plasmid by methanol and expressing the recombinant plasmid to obtain the recombinant lysozyme after purification for cation resin chromatographic column. The method adopts genetically engineered vaccine strains to produce lysozyme, is suitable for large-scale culture and extraction separation, and has the advantages of simple processing technology, simple equipment requirement, short production period, lower cost and no environment pollution. The activity of the prepared recombinant holothurian lysozyme is increased by 30 percent compared with the lysozyme extracted from holothurian tissues; and compared with egg-white lysozyme, the recombinant holothurian lysozyme has far wider bacteriostatic spectrum range, and particularly has more remarkable bacteriostatic effect for Gram-negative bacteria which can not be acted by the egg-white lysozyme.
Owner:DALIAN POLYTECHNIC UNIVERSITY

Plant extract-based sterilization composition and baby care composition

The invention discloses a plant extract-based sterilization composition. The plant extract-based sterilization composition is prepared from the following components in percentage by weight: 1.0 to 3.0percent of grapefruit extract, 3.0 to 10.0 percent of cortex magnoliae officinalis extract, 3.0 to 8.0 percent of ginger root extract, 3.0 to 8.0 percent of pericarpium zanthoxyli extract and 71 to 90 percent of polyol. The plant extract-based sterilization composition is prominent in lasting antibacterial property; the plant extract-based sterilization composition is prepared from the grapefruitextract, the cortex magnoliae officinalis extract, the ginger root extract, the pericarpium zanthoxyli extract and the polyol, so that the plant extract-based sterilization composition is capable ofeffectively controlling plenty of bacteria and mould, which are difficult to control, in cosmetics, and the plant extract-based sterilization composition is gentle in property, has no irritation and no hotness and is very safe. The plant extract-based sterilization composition is capable of effectively killing the bacteria, the mould and saccharomycetes in the cosmetics, and the components of thecomposition are not included in an accepted preservative list specified by Cosmetic Safety Technological Specification, and can meet the requirement of a 'no preservative' concept of a product.
Owner:广州天然国度生物科技有限公司

Preparation method of nanomaterial for preventing decayed teeth and treating superficial caries

The invention discloses a preparation method of a nanomaterial for preventing decayed teeth and treating superficial caries, and relates to the fields of nano-biotechnologies and oral care technologies. The preparation method comprises the following steps: uniformly dispersing polydopamine particles in an aqueous solution system, adding an aqueous solution containing silver ions under a magnetic stirring condition, carrying out a reaction for a period of time, performing high-speed centrifuging, discarding the obtained supernatant, and washing the obtained reaction product with deionized water; and slowly adding an aqueous solution of molecules having the ability to recognize dental enamel to a high-speed stirred catalyst system solution, carrying out a reaction for a period of time, slowly adding the prepared antibacterial component-immobilized core aqueous solution to the obtained high-speed stirred solution system, carrying out a reaction for a period of time, performing high-speedcentrifugation, discarding the obtained supernatant, washing the obtained reaction product with deionized water to obtain the nanomaterial. The nanomaterial prepared by the preparation method is formed by the inner nanoparticle core having an induced mineralization effect, and an external containing the above broad-spectrum antibacterial component and the dental enamel recognition molecules.
Owner:合肥诺创新材料科技有限公司

Method for separating plant antimicrobial peptide, plant antimicrobial peptide and application of plant antimicrobial peptide

The invention provides a method for separating a plant antimicrobial peptide, the plant antimicrobial peptide and application of the plant antimicrobial peptide. The method for separating the plant antimicrobial peptide comprises the following steps that a certain mass of black sesame is taken, and an acetic acid solution is added into the black sesame; the black sesame and the acetic acid solution are subjected to ultrasonic treatment in an ultrasonic generator and then filtered to obtain an extract; the extract is heated in a water bath and then cooled to the room temperature; the extract iscentrifuged, a precipitate is discarded, and a supernatant is collected; the supernatant is dialyzed and concentrated in sequence to obtain a reverse phase chromatographic sample; the reverse phase chromatographic sample is subjected to reverse phase high performance liquid chromatography to obtain the isolated plant antimicrobial peptide. The method for separating the plant antimicrobial peptide, the plant antimicrobial peptide and application of the plant antimicrobial peptide have the advantages that the black sesame is used as a raw material for direct extraction, the cumbersome processesof peeling and degreasing are omitted, application of organic reagents is reduced, the operation difficulty is reduced, the production efficiency is improved, the production cost is reduced, and themethod is in accordance with industrial production. The prepared black sesame antibacterial peptide has a broad-spectrum antibacterial effect and a strong antibacterial effect on candida albicans, pseudomonas aeruginosa, staphylococcus aureus, escherichia coli and haemophilus influenzae and can be widely applied in in-vitro killing products, poultry and livestock feed additives and other fields.
Owner:吉林省诚仁达医疗技术发展有限公司
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