64results about How to "Good broad-spectrum antibacterial properties" patented technology

The invention discloses a sepiolite-typed inorganic antimicrobial agent with compound metal antimicrobial ion and a preparation method, which belongs to the field of antimicrobial material. The invention is characterized in that the natural sepiolite with low cost is adopted as carrying material, and then after activation modification, the sepiolite carries compound silver ion and zinc ion or compound silver ion and copper ion with the method of ion exchange and absorption, therefore, the inorganic antimicrobial agent with strong antimicrobial capability is prepared well. The compound antimicrobial agent provided by the invention has simple preparation process, low cost, no discoloration, strong broad-spectrum antimicrobial capability and a wide range of use. The invention not only can be used as antimicrobial material separately, but also can be added into a plurality of materials, such as plastic, coating, fiber, ceramic, decorative and architectural material and daily cosmetic, therefore, product with antimicrobial property can be prepared for application. Meanwhile, as the sepiolite carrier has good rheological property, thermal stability, dispersion, mechanical strength and other good properties, overall performance of the product can be improved.

The invention provides a non-woven composite material for a filter respirator.The non-woven composite material comprises a first non-woven fabric layer, a second non-woven fabric layer and a third non-woven fabric layer sequentially from top to bottom, wherein a first antibacterial layer and a polytetrafluoroethylene micro-porous membrane layer are sequentially arranged between the first non-woven fabric layer and the second non-woven fabric layer, a second antibacterial layer and a detachable filter layer are sequentially arranged between the second non-woven fabric layer and the third non-woven fabric layer, the first antibacterial layer is a porous nano titanium dioxide silver-loaded antibacterial agent coating with the particle size of l5nm-50 nm, and the second antibacterial layer is a biological polypeptide antibacterial agent layer.The non-woven composite material for the filter respirator can effectively filter very fine particles and meanwhile has high bacterium and virus resistance performance and good air permeability and adsorbability.

The invention discloses a preparation method of guanidine polymer fungicides. The preparation method includes that mass polymerization is adopted, and polymerization reaction is divided into two stages: prepolymerization and condensation; guanidine salt and endamine-based polymers are placed in a reaction kettle to be evenly mixed; the mass ratio of the guanidine salt to the endamine-based polymers is 1:10-1:1; under nitrogen protection, temperature is raised to 70-100DEG C for refluxing reaction in stirring, and guanidyl containing low polymers are obtained; polyamine small molecules are added to the reaction kettle to be evenly mixed; the mass ratio of the polyamine small molecules to the guanidine salt is 1:4-2:1; under nitrogen protection, temperature is raised to 120-200DEG C for refluxing reaction in stirring, and the guanidine polymers are obtained. The preparation method is simple in process and easy to implement and high in yield; the guanidine polymers contain a great deal of reactive amine on the basis of retaining fungicidal-group guanidyl, grafting to the surface of the product in the subsequent steps is facilitated, and the fungicides are good in practicability and application prospect.

The invention discloses a water-soluble quaternary ammonium salinized carbon nanosphere. The water-soluble quaternary ammonium salinized carbon nanosphere is prepared via reaction between a high-molecular compound with an amino group and alkyl betaine, and comprises a carbon nanosphere mainly formed by carbon and the alkyl betaine grafted on the surface of the carbon nanosphere. The invention further discloses a preparation method of the water-soluble quaternary ammonium salinized carbon nanosphere and an application of the antibacterial aspect. Compared with the prior art, the invention completes the chemical grafting of the high-molecular compound with the amino group and the alkyl betaine and carbon nanometer granulation through a hydrothermal method by one step, and the prepared carbon nanosphere is good in water solubility, relatively low in cytotoxicity and excellent in broad-spectrum antibacterial performance.

The invention provides an antibacterial chitosan dressing containing nanogold. The antibacterial chitosan dressing containing the nanogold is chitosan fabric containing and / or being attached with gold nanoparticles with the antibacterial effect. The prepared antibacterial chitosan dressing containing the nanogold has excellent broad-spectrum antibacterial property and does not have bacterial resistance, the antibacterial nanogold which is small in toxicity to human cells is added into the chitosan dressing, the dressing has the broad-spectrum antibacterial property and the effect of being small in toxicity to the human cells of the nanogold and the good effects of promoting healing and stopping bleeding and the biodegradability and biocompatibility of chitosan, the dressing can be used for clinical wound treatment and treatment on various wound infections such as burns, scalds and bedsore infections, and the dressing is an extremely good medical dressing. The invention further provides a preparation method and application of the antibacterial chitosan dressing.

The invention belongs to the technical field of material science and engineering, and discloses a low-molecular chitosan @ silver nanoparticle compound film and a preparation method thereof and applications in the field of antibacteria and anti-corrosion. The preparation method of the invention comprises the following steps: adding enzyme powder into a buffer solution of macromolecular chitosan, conducting reaction with stirring for 10-14h at 30-60 DEG C, adding a H2O2 solution, conducting reaction at 50-80 DEG C for 20-60min, conducting heating for 5-10min at 90-110 DEG C, and conducting pumping filtration, separation, heating and activation to obtain a low-molecular chitosan final product; adding the low-molecular chitosan final product and polyvinyl alcohol into water, conducting uniform mixing, adding an AgNPs dispersion liquid, conducting stirring at 30-90 DEG C for 4-5h, and conducting stirring for 1-2h in a cell pulverizer to obtain an electrostatic spinning solution; and conducting spinning to obtain the low-molecular chitosan @ silver nanoparticle compound film. The compound film of the invention has excellent performance, has stronger antibacterial effects and bacteria interception capability, and can be applied to the fields of the antibacterial and the anti-corrosion.

The invention provides synthesis for biodegradable amphiphilic block copolymerization antibacterial peptoids, a preparation method of antibacterial peptoid vesicles and applications of the antibacterial peptoid vesicles. The synthesis for the antibacterial peptoids comprises the following steps: a hydrophilic polypeptide chain segment containing an amino protective group, a hydrophobic polymer chain segment of which one end is amino-terminated and isocyanate radicals of a diisocyanate unit are connected through covalent bonds, and therefore the antibacterial peptoids are obtained; and the antibacterial peptoid vesicles are formed by self assembly of the antibacterial peptoids, and the antibacterial peptoid vesicles can be used as antibacterial agents or drug carriers to be applied to aspects such as clinical inflammation resistance, anti-cancer drug targeting release, or nanomedicine. The antibacterial peptoid vesicles select and use the biodegradable hydrophobic polymer chain segment to replace a hydrophobic amino acid chain segment in an antibacterial peptide, thus the antibacterial peptoid vesicles do not have cytotoxicity, and have excellent biocompatibility and biodegradability; and besides, the antibacterial peptoid vesicles have a broad-spectrum antibacterial property, and a membrane damage antibacterial mechanism which is similar to that of a natural antibacterial peptide, and therefore drug tolerance of germs is not easily induced.

The invention provides anamphiphilic multi-block antibacterial peptide copolymer, and a preparation method and application thereof. According to the amphiphilic multi-block antibacterial peptide copolymer,a hydrophobic amino acid block and a hydrophilic amino acid block are selected and usedfor simulating and replacingan amino acid composition in natural antibacterial peptide, therefore, excellentbroad-spectrum antibacterial performance, low cytotoxicity, excellent biocompatibility and biodegradability are achieved, an antibacterial mechanism of the amphiphilic multi-block antibacterial peptide copolymer is the same as that of the natural antimicrobial peptide, bacteria die by destroying bacterial cell membranes, andthe bacteria is not prone to being inducedto produce drug resistance.According to synthesis steps of the preparedamphiphilic multi-block antimicrobial peptide copolymer is simpler, efficient and lower in production cost compared with step-by-step synthesis reaction, and the amphiphilic multi-block antibacterial peptide copolymer can be used as an antimicrobial agent or drug carriers to be used in aspects of clinical anti-infection, targeted release of anticancer drugsor nanomedicine.

The invention provides a full-nanofiber electronic skin which comprises an upper nanofiber membrane, a middle nanofiber membrane and a lower nanofiber membrane which are a contact electrification layer, a middle electrode layer and a bottom supporting layer respectively. The contact electrification layer and the bottom supporting layer are both nanofiber membranes made of biodegradable materials.And the middle electrode layer is a nanofiber membrane with a sterilization function and is electrically connected with the ground or other conductors. The electronic skin is provided with a pluralityof layers of staggered nanofiber networks and a large number of three-dimensional micro-nano hierarchical pores, so that the electronic skin has air permeability, high output, high pressure sensitivity and antibacterial property.

The invention provides an antibacterial peptoid and a vesicle and a preparation method and application thereof. A hydrophilic part of the antibacterial peptoid is a lysine residue, and a hydrophobic part of the antibacterial peptoid is a diisocyanate unit, and the lysine residue links with the diisocyanate unit by means of a covalent bond. The antibacterial drug-loading vesicle is formed by self-assembling of the antibacterial peptoid and a drug in a mixture of an organic solvent and water. The antibacterial peptoid of the invention has a similar structure to that of a natural cationic anti-microbial peptide, and thus has a similar antibacterial mechanism; the antibacterial peptoid has broad-spectrum antibacterial properties, and cause the bacteria to be hard to produce drug resistance thereto; the antibacterial drug-loading vesicle has both antibacterial effect and dug-loading function, and can achieve sustained drug release.

The invention provides antibacterial gel containing nano gold. The antibacterial gel is prepared from the following components in percentage by weight: 0.5%-2% of a gel matrix, 0-2% of an alkaline substance, 0-20% of a humectant, 0-20% of ethanol, no more than 0.5% of nano-particles having an antibacterial function and containing the nano gold, 0-0.2% of a preservative and water. The antibacterial gel containing the nano gold, provided by the invention, has an excellent broad-spectrum antibacterial property and the toxicity to human body cells is much lower than that of antibacterial gel which is sold in the market and contains nano silver or other silver ions; the gel does not cause pain feeling on patients and has relatively strong patient adaptability; and the antibacterial gel can be used for various types of wounds, gynecological diseases and anorectal diseases and can also be matched with traditional wound dressing.

The invention provides an antibacterial non-woven fabric and a preparation method thereof. The preparation method comprises the following steps of firstly, preparing a polyvinylidene fluoride / hydrophilic polyurethane composite fiber non-woven fabric, and then performing electron beam radiation treatment on the composite fiber non-woven fabric; then immersing the composite fiber non-woven fabric into an antibacterial agent ionic liquid for grafting reaction; and finally, performing extracting with methanol and performing vacuum drying to obtain the successfully grafted antibacterial non-woven fabric. According to the preparation method, a polyvinylidene fluoride polymer is taken as a fiber main body, and hydrophilic polyurethane is introduced for composite spinning, so that the mechanical property and the hydrophilic property of the prepared antibacterial non-woven fabric are remarkably improved. By utilizing the grafting reaction of the polyvinylidene fluoride polymer and the antibacterial agent ionic liquid, the prepared antibacterial non-woven fabric is excellent in broad-spectrum antibacterial property, and the sterilizing rate of staphylococcus aureus reaches 99 percent or above.

The invention provides a non-toxic marine ship antifouling coating material, which is prepared from the following raw materials in parts by mass: 100 parts of organic silicon resin, 1 to 3 parts of achitosan quaternary ammonium salt, 5 to 10 parts of fly ash nanoparticles, 0.5 to 1 part of a coupling agent, 3-5 parts of a curing agent, 0.01 to 0.1 part of a catalyst, 0.2 to 0.5 part of an antifoaming agent, and 0.2 to 0.5 part of a leveling agent. According to the invention, organic silicon resin is used as a matrix, nano fly ash is used as a carrier, and a chitosan quaternary ammonium salt loaded on the surface is used as a main antifouling agent, wherein the chitosan quaternary ammonium salt has good solubility and antibacterial property, has biocompatibility, and is safe and non-toxic,the fly ash nanoparticles have strong alkalinity, and the organic silicon is also a low surface energy material; by using a hydrophilic chitosan quaternary ammonium salt as a main antibacterial material, so that the use of a large amount of organic solvents is avoided, the cost is low, and less waste liquid is generated; and fly ash nanoparticles are activated to promote the self-polymerization of organic silicon resin molecules to form a layered structure with certain orientation so as to enhance the strength and elastic modulus of the coating material.

The invention provides a method for efficiently preparing a recombinant antibacterial peptide PaDef in pichia pastoris. The method comprises the following steps: taking pichia pastoris as a host cell, modifying a gene sequence of the antibacterial peptide PaDef (the antibacterial peptide PaDef is named as mPaDef), inserting the antibacterial peptide mPaDef into a pPICZalphaA vector, successfully transferring the vector into pichia pastoris GS115, performing inducible expression with methanol and performing purification and activity identification on an expression product. A final product is a high expression strain of the recombinant antibacterial peptide mPaDef, and the yield of the recombinant antibacterial peptide in supernatant of fermentation liquor is 84mg / L. The prepared recombinant antibacterial peptide has broad-spectrum antibacterial activity and good temperature and protein stability and is comparatively good in stability in weak acid, neutral and alkaline environments.

The invention relates to a production process for dried cattle beef. The production process comprises a raw meat soaking and blood removing step, a raw meat segmenting step, a cropping step, a cutting step, a preparing and frying step, a baking step, a cooling step, a high-temperature sterilizing step, a vacuum packaging step and a storing step. In the steps, the added spice comprises the following raw materials in parts by weight: 10-12 parts of amomum, 10-12 parts of cardamom, 10-12 parts of clove, 10-12 parts of costus root, 10-12 parts of cinnamon, 10-12 parts of amomum tsao-ko, 2-4 parts of rhizoma kaempferiae, 20-22 parts of anise, 20-22 parts of spikenard, 20-22 parts of patchouli, 20-22 parts of sinomenium acutum aroma, 1-3 parts of lithospermum, 1-3 parts of Ricepaperplant Pith , 1-3 parts of lysimachia foenum-graecum, 1-3 parts of licorice root, 10-12 parts of lysimachia sikokiana, 20-22 parts of fennel, 1-3 parts of dried orange peel and 2-4 parts of bay leaf. Compared with the prior art, the production process disclosed by the invention has the advantages the fishy flavor removing and refresh keeping effects can be enhanced, the excellent mouthfeel of the dried cattle beef can be still maintained after the dried cattle beef is stored for six months; and the used spice is lower in cost and natural in components, has a dietary therapy function and anti-oxidation function and benefits the health.

The invention discloses an amorphous carbon-based space antibacterial wear-resistant solid lubricating composite film layer and a preparation method thereof. The composite film layer comprises a base layer, a metal doped amorphous carbon transition layer, an undoped amorphous carbon layer, a first Cu / Ag co-doped amorphous carbon transition layer, a Cu / Ag co-doped amorphous carbon layer, a second Cu / Ag co-doped amorphous carbon transition layer and an undoped amorphous carbon layer which are arranged in sequence. Aiming at the requirements of a space residence cabin environment for an antibacterial lubricating anti-friction coating layer, through the structural design of the coating layer, the base supporting layer, the transition layers, the functional layers and other different layers are matched with one another, and the two antibacterial elements Ag and Cu are compounded and introduced into the coating layer, the coating layer has the anti-friction and wear-resistant characteristics, and meanwhile is resistant to gram-negative bacteria represented by escherichia coli and gram-positive bacteria represented by staphylococcus aureus, and the good broad-spectrum antibacterial property is achieved. The film layer can well improve the antibacterial property and the lubricating property of moving parts of a space station.

The invention relates to a method for preparing silver-loaded chitosan medical dressing by utilizing loquat leaves or loquat kernel extract. The method comprises the following steps: extracting effective ingredients of the loquat leaves or loquat kernels by using a leaching method to obtain extract of the loquat leaves or loquat kernels; reducing silver nitrate with the extract to prepare a nano-silver aqueous solution; and finally immersing a chitosan fiber non-woven fabric with the nano-silver aqueous solution to obtain the silver-loaded chitosan medical dressing with excellent antibacterial effect. The method has the characteristics of simple process, ecological friendliness, quick action, high efficiency, safety, no toxicity and the like; the silver-loaded chitosan medical dressing prepared by treating the chitosan fiber non-woven fabric with nano-silver has excellent broad-spectrum antibacterial property and durable antibiotic efficiency, and has an antibacterial rate over 98 percent even being washed for multiple times.

The invention discloses an antibacterial high-strength ultrathin composite membrane material, a preparation method thereof, and application of the material in uranium enrichment in uranium-containing wastewater or seawater. The composite membrane material is formed by dispersing and fixing a polypropylene amidoxime (PAO) functional material in a cross-linked network formed by sulfonated cellulose nanocrystals (CNC) and chitosan quaternary ammonium salt (QCS). The preparation method comprises the following steps: mixing a PAO solution and a CNC solution, sequentially adding a wet strength agent and a QCS solution, oscillating and mixing, and carrying out injection molding and drying molding to obtain the composite membrane material with high mechanical strength, broad-spectrum antibacterial performance and excellent uranium adsorption function. The uranium adsorption capacity of the composite membrane material to unfiltered seawater containing 16 ppm of uranium reaches 312 + / -17.5 mg / g, the uranium adsorption capacity of the composite membrane material to untreated natural seawater containing 16 ppm of uranium reaches 9.67 mg / g, the mechanical strength of the composite membrane material reaches 18.7 MPa, the service life of the composite membrane material is long, after seven times of adsorption-desorption circulation, good uranium absorption performance can still be kept, and the composite membrane material can be widely applied to uranium extraction in seawater or uranium-containing wastewater and uranium-containing wastewater treatment.

The invention relates to natural nonirritating wet wipe soaking solutions. The natural nonirritating wet wipe soaking solutions are prepared from the following components in parts by weight: 100 to 150 parts of pure water, 5 to 6 parts of glycerol, 1 to 2 parts of white vinegar, 1 to 2 parts of hydrogen peroxide, 10 to 12 parts of fructus forsythia extract liquid, 5 to 10 parts of common fibraurea stem extract liquid, 5 to 10 parts of honeysuckle flower extract liquid, 1 to 2 parts of liquid-state menthol, and 0.1 to 0.2 part of polyoxyethylene hydrogenated castor oil. By using a combination of common fibraurea stem extract liquid and the honeysuckle flower extract liquid as well as the white vinegar and the hydrogen peroxide as antibacterial agents, the combination is mild and nonirritating to the skin, and the antibacterial effect is strong; the conventional propylene glycol is replaced by the glycerol subjected to ultrasonic emulsification, and the glycerol is used as a wetting agent, so that the glycerol has a preferable moisture effect and also has functions of moistening the skin and locking moisture; the fructus forsythia extract liquid is used as the preservative, is purely natural, and has no harm to the human body after the preservative is used for a long time; and meanwhile, various types of plant extract liquid coordinate with the liquid-state menthol, so that the soaked solutions smell freshly and elegantly and are refreshing.

The invention provides a preparation method of a medical non-woven fabric composite. The method specifically includes the following steps of firstly, weighing 30-50 parts by weight of adipic acid / polybutylene terephthalate, 20-30 parts by weight of polybutylene terephthalate and 30-40 parts by weight of polycarbonate to be sufficiently mixed to obtain a mixture A; secondly, blending the mixture in the first step with 1-4 parts by weight of antistatic agent and 0.5-2 parts by weight of antibacterial agent, and conducting extruding and granulating through a twin-screw extruder to obtain a blend; thirdly, conducting vacuum drying on the blend in the second step, conducting heating, fusing, extruding, stretching, cooling and self-adhering on the dried blend through a screw extruder to form a non-woven fabric; fourthly, spraying an anti-radiation layer on one side of the non-woven fabric obtained in the third step, and putting the fabric into a drying box to be dried and shaped. The prepared medical non-woven fabric composite has antibacterial performance, radiation prevention performance and antistatic performance and is mainly applied to preparing a medical mask.

The invention discloses a preparation method of martensitic stainless steel having broad-spectrum antimicrobial effects. The preparation method provided by the invention is characterized by comprising the following steps of 1, before smelting, melting Ag and Cu into an intermediate alloy according to ratios and adding the intermediate alloy as an auxiliary material into raw metals, 2, carrying out smelting by an electric furnace-AOD-VOD and carrying out pouring, 3, carrying out hot rolling, carrying out annealing at a temperature of 860 to 880 DEG C, carrying out cold rolling, carrying out annealing at a temperature of 1030 to 1050 DEG C, and carrying out acid-washing and polishing, and 4, carrying out antibacterial treatment through carrying out heat preservation at a temperature of 1160to 1180 DEG C for 1 to 2 hours and cooling in air to a room temperature, and carrying out aging treatment through carrying out heat preservation at a temperature of 530 to 550 DEG C for 8 to 10 hoursfor aging treatment and cooling in air.

The invention discloses a preparation method of an antibacterial waterproofing moisture-permeable polyurethane thin film. The method includes: 1) preparing a modified composition; 2) performing surface modification on antibacterial composite filler; 3) preparing antibacterial enhancing modified polyurethane resin; 4) preparing the polyurethane composite thin film. In the invention, molybdenum tailings, bamboo charcoal powder and nano TiO2 are subjected to the surface modification and then are added to the waterborne polyurethane resin during synthesis, thus preparing the inherent-antibacterialenhanced polyurethane resin; then the polyurethane resin is physically blended with a beta-cyclodextrin / tetrahydrofuran composite in the presence of nano silver antibacterial solution to prepare thethin film. The composite thin film has excellent broad-spectrum antibacterial property, mechanical performance, water resistance and breathability and waterproofing function, is excellent in comprehensive performance and has extensive market prospect.

The invention discloses a preparation method of a decoration coating material for building construction, and particularly relates to the technical field of decoration coating material preparation. Thedecoration coating material comprises the following raw materials by weight: 100-200 parts of an acrylate aqueous solution, 30-50 parts of titanium dioxide, 40-60 parts of calcium carbonate, 50-60 parts of silica powder, 1-2 parts of hydroxyethyl cellulose, 20-30 parts of quicklime, 6-8 parts of chitosan, 10-20 parts of aloe, 10-20 parts of artemisia argyi and 6-8 parts of ultraviolet-proof powder, wherein the auxiliary materials comprise the following components in parts by weight: 2-4 parts of a defoaming agent, 4-8 parts of a dispersing agent, 2-6 parts of a film aid, 2-4 parts of a preservative, 2-4 parts of an anti-freezing agent and 60-80 parts of water. By adding lime water, chitosan, aloe extracting solution and artemisia argyi extracting solution, the prepared coating material has antibacterial and bactericidal functions, can prevent rot and mildew phenomena, can protect wall surfaces, and is non-toxic and harmless to a human body, safe and environment-friendly.

The invention provides nanogold-containing antibacterial cream which is prepared from the following components in percentage by weight: 24 to 34 percent of an oil phase, 3 to 5 percent of an emulsifier, 5 to 10 percent of a humectant, 0.001 to 1 percent of antibacterial nanogold-containing nano particles, 0 to 0.01 percent of a preservative and water. The antibacterial cream is excellent in broad-spectrum antibacterial property; the toxicity to human body cells is much lower than that of commercially available antibacterial cream containing nanosilver or other silver ions; with the cream, a patient does not have a pain feeling, and the cream is higher in patient applicability, can be applied to treatment of various burns and scalds, bedsore infections, various wound infections, skin inflammations such as tinea of feet and hands, gynecological diseases such as female genital tract inflammation, cervicitis and cervical erosion, and anorectal diseases such as proctitis, and also can be cooperated for conventional wound dressing.

The invention provides a broad-spectrum antibacterial non-woven fabric as well as a preparation method and application thereof. The method comprises the following steps of providing an aqueous solution of an antibacterial agent; impregnating a non-woven fabric base material in the aqueous solution of the antibacterial agent to obtain an impregnated base material; and drying the impregnated base material to obtain the dried non-woven fabric, wherein the antibacterial agent comprises the following components in percentage by weight of 1%-5% of quaternary ammonium salt, 10%-20% of antibacterial peptide, 3%-4% of a surfactant and the balance of an inorganic solvent, and based on the weight of the aqueous solution of the antibacterial agent being 100%, the antibacterial agent accounts for 10%-40% of the weight of the aqueous solution of the antibacterial agent. The antibacterial non-woven fabric disclosed by the invention has a good broad-spectrum antibacterial effect.

The invention relates to the field of antibacterial materials, in particular to guanidyl hyaluronic acid type antibacterial hydrogel as well as a preparation method and application thereof. Alkyl guanidines with different chain lengths are successfully connected to a carboxyl end side chain of hyaluronic acid in a chemical bond mode through a series of reactions, hyaluronic acid is endowed with antibacterial performance, and then guanidyl hyaluronic acid type antibacterial hydrogel is obtained through a ring-opening polymerization reaction by using a glycol diglycidyl ether crosslinking agent. The guanidyl hyaluronic acid type antibacterial hydrogel can also effectively inhibit the growth of bacteria and prevent wound infection, is an excellent antibacterial gel auxiliary material, and shows excellent antibacterial performance on gram-negative bacteria such as escherichia coli and gram-positive bacteria such as staphylococcus aureus; the cell compatibility is good; reaction conditions are easy to control, cost is low, and raw materials are easy to obtain; the antibacterial dressing can be used for wound injury, and has a good application prospect.

The invention discloses a zinc germanate matrix sustained-released antibacterial nano material capable of monitoring afterglow light and a preparation method thereof, and belongs to the field of preparation of antibacterial nano materials. The chemical composition general formula of the zinc germanate matrix antibacterial nano material is Zn2GeO4: xM, x is greater than or equal to 0.001 and less than or equal to 0.02, Zn2GeO4 is a matrix, and M is a metal ion with an antibacterial effect. The zinc germanate matrix antibacterial nano material is synthesized by a hydrothermal method, is simple to prepare and low in cost, and can be used for industrial production; the material has excellent broad-spectrum antibacterial performance at a bacterial infection part, metal ion slow release can maintain high antibacterial concentration for a long time, the antibacterial period is long, and the possibility of inducing bacteria to generate drug resistance is extremely low; and in a subacid environment of a bacterial infection part, the afterglow light intensity of the material changes along with degradation of the material, and real-time monitoring of the antibacterial process of the infection part can be realized by utilizing the change of the afterglow intensity.

The invention provides an amphiphilic grafted copolymer containing an antibacterial peptide, and a preparation method and applications thereof. The amphiphilic grafted copolymer is prepared through connection of hydrophobic high molecular chain segments and the antibacterial peptide through covalent bonds, and is used in clinical infection prevention, anticancer medicine targeting release, or nanometer medical science as an antibacterial agent or a drug carrier. According to the preparation method, the hydrophobic high molecular chain segments excellent in biocompatibility are adopted to replace hydrophobic amino acid chain segments in the antibacterial peptide, so that no cytotoxicity is caused, and excellent biocompatibility and biodegradability are achieved; and in addition, the amphiphilic grafted copolymer possesses excellent wide spectrum antibacterial properties, and membrane destroy antibacterial mechanism similar to that of natural antibacterial peptides, so that generation ofbacterium drug resistance is not easily induced. The amphiphilic grafted copolymer containing an antibacterial peptide is controllable in structure, synthesis steps are simple and convenient, production cost is low, and industrialized production can be realized.

The invention discloses a synthesis method of O-quaternized vanilla-based chitosan carbon residue particles based on an amphiphilic biological carbon material, and belongs to the technical field of biology. The synthesis method comprises the following steps: preparing an amphiphilic biological carbon material from beer yeast cells by adopting a hydrothermal synthesis method, grafting chitosan by adopting a covalent binding method by taking the amphiphilic biological carbon material as a carrier, and carrying out structure modification on chitosan carbon residue particles by adopting a chemical method by taking vanillin and glycidyl trimethyl ammonium chloride as modified materials, and obtianing the functionalized carbon residue particles. A series of characterization means verify successful covalent modification of chitosan, vanillin and glycidyl trimethyl ammonium chloride. The functionalized carbon residue particles synthesized by the invention still have high dispersity in polar and non-polar solvents while retaining the advantage of antibacterial property of quaternized chitosan. The synthesis method is simple in process and low in cost. The synthetic product is low in irritation, good in biocompatibility, excellent in antibacterial property and good in amphipathy.

The invention relates to the technical field of edible packaging materials, in particular to an edible antibacterial film and a preparation method thereof. Raw materials comprise dissolving pulp, a cationic etherifying agent, methyl cellulose, wheat gluten protein, glycerol, lipids and a natural antibacterial agent. Electrostatic repulsion and steric hindrance effects among molecules of the cationic modified cellulose nanofibril are utilized, so that uniform distribution of the nanofibril in an edible film matrix is facilitated, and the nano-sized reinforcing and toughening effects of the nanofibril are brought into full play; by means of the long-acting stable antibacterial effect of the grafted quaternary ammonium salt group and in combination with the addition of the natural quick-acting antibacterial agent, the edible film is endowed with a good antibacterial effect, the shelf life of a packaged product is prolonged, and the product quality is improved; and besides, the selected raw materials are natural edible macromolecular polymers, so that the edible composite film has no toxic or side effect on a human body and is low in cost, dependence and use of petroleum resources arereduced, and the edible composite film is simple in preparation process and convenient to operate, thereby having a relatively good market application prospect.