64results about How to "Good broad-spectrum antibacterial properties" patented technology

The invention discloses a sepiolite-typed inorganic antimicrobial agent with compound metal antimicrobial ion and a preparation method, which belongs to the field of antimicrobial material. The invention is characterized in that the natural sepiolite with low cost is adopted as carrying material, and then after activation modification, the sepiolite carries compound silver ion and zinc ion or compound silver ion and copper ion with the method of ion exchange and absorption, therefore, the inorganic antimicrobial agent with strong antimicrobial capability is prepared well. The compound antimicrobial agent provided by the invention has simple preparation process, low cost, no discoloration, strong broad-spectrum antimicrobial capability and a wide range of use. The invention not only can be used as antimicrobial material separately, but also can be added into a plurality of materials, such as plastic, coating, fiber, ceramic, decorative and architectural material and daily cosmetic, therefore, product with antimicrobial property can be prepared for application. Meanwhile, as the sepiolite carrier has good rheological property, thermal stability, dispersion, mechanical strength and other good properties, overall performance of the product can be improved.

The invention provides a non-woven composite material for a filter respirator.The non-woven composite material comprises a first non-woven fabric layer, a second non-woven fabric layer and a third non-woven fabric layer sequentially from top to bottom, wherein a first antibacterial layer and a polytetrafluoroethylene micro-porous membrane layer are sequentially arranged between the first non-woven fabric layer and the second non-woven fabric layer, a second antibacterial layer and a detachable filter layer are sequentially arranged between the second non-woven fabric layer and the third non-woven fabric layer, the first antibacterial layer is a porous nano titanium dioxide silver-loaded antibacterial agent coating with the particle size of l5nm-50 nm, and the second antibacterial layer is a biological polypeptide antibacterial agent layer.The non-woven composite material for the filter respirator can effectively filter very fine particles and meanwhile has high bacterium and virus resistance performance and good air permeability and adsorbability.

The invention discloses a preparation method of guanidine polymer fungicides. The preparation method includes that mass polymerization is adopted, and polymerization reaction is divided into two stages: prepolymerization and condensation; guanidine salt and endamine-based polymers are placed in a reaction kettle to be evenly mixed; the mass ratio of the guanidine salt to the endamine-based polymers is 1:10-1:1; under nitrogen protection, temperature is raised to 70-100DEG C for refluxing reaction in stirring, and guanidyl containing low polymers are obtained; polyamine small molecules are added to the reaction kettle to be evenly mixed; the mass ratio of the polyamine small molecules to the guanidine salt is 1:4-2:1; under nitrogen protection, temperature is raised to 120-200DEG C for refluxing reaction in stirring, and the guanidine polymers are obtained. The preparation method is simple in process and easy to implement and high in yield; the guanidine polymers contain a great deal of reactive amine on the basis of retaining fungicidal-group guanidyl, grafting to the surface of the product in the subsequent steps is facilitated, and the fungicides are good in practicability and application prospect.

The invention discloses a water-soluble quaternary ammonium salinized carbon nanosphere. The water-soluble quaternary ammonium salinized carbon nanosphere is prepared via reaction between a high-molecular compound with an amino group and alkyl betaine, and comprises a carbon nanosphere mainly formed by carbon and the alkyl betaine grafted on the surface of the carbon nanosphere. The invention further discloses a preparation method of the water-soluble quaternary ammonium salinized carbon nanosphere and an application of the antibacterial aspect. Compared with the prior art, the invention completes the chemical grafting of the high-molecular compound with the amino group and the alkyl betaine and carbon nanometer granulation through a hydrothermal method by one step, and the prepared carbon nanosphere is good in water solubility, relatively low in cytotoxicity and excellent in broad-spectrum antibacterial performance.

The invention provides an antibacterial chitosan dressing containing nanogold. The antibacterial chitosan dressing containing the nanogold is chitosan fabric containing and/or being attached with gold nanoparticles with the antibacterial effect. The prepared antibacterial chitosan dressing containing the nanogold has excellent broad-spectrum antibacterial property and does not have bacterial resistance, the antibacterial nanogold which is small in toxicity to human cells is added into the chitosan dressing, the dressing has the broad-spectrum antibacterial property and the effect of being small in toxicity to the human cells of the nanogold and the good effects of promoting healing and stopping bleeding and the biodegradability and biocompatibility of chitosan, the dressing can be used for clinical wound treatment and treatment on various wound infections such as burns, scalds and bedsore infections, and the dressing is an extremely good medical dressing. The invention further provides a preparation method and application of the antibacterial chitosan dressing.

The invention belongs to the technical field of material science and engineering, and discloses a low-molecular chitosan @ silver nanoparticle compound film and a preparation method thereof and applications in the field of antibacteria and anti-corrosion. The preparation method of the invention comprises the following steps: adding enzyme powder into a buffer solution of macromolecular chitosan, conducting reaction with stirring for 10-14h at 30-60 DEG C, adding a H2O2 solution, conducting reaction at 50-80 DEG C for 20-60min, conducting heating for 5-10min at 90-110 DEG C, and conducting pumping filtration, separation, heating and activation to obtain a low-molecular chitosan final product; adding the low-molecular chitosan final product and polyvinyl alcohol into water, conducting uniform mixing, adding an AgNPs dispersion liquid, conducting stirring at 30-90 DEG C for 4-5h, and conducting stirring for 1-2h in a cell pulverizer to obtain an electrostatic spinning solution; and conducting spinning to obtain the low-molecular chitosan @ silver nanoparticle compound film. The compound film of the invention has excellent performance, has stronger antibacterial effects and bacteria interception capability, and can be applied to the fields of the antibacterial and the anti-corrosion.

The invention provides antibacterial gel containing nano gold. The antibacterial gel is prepared from the following components in percentage by weight: 0.5%-2% of a gel matrix, 0-2% of an alkaline substance, 0-20% of a humectant, 0-20% of ethanol, no more than 0.5% of nano-particles having an antibacterial function and containing the nano gold, 0-0.2% of a preservative and water. The antibacterial gel containing the nano gold, provided by the invention, has an excellent broad-spectrum antibacterial property and the toxicity to human body cells is much lower than that of antibacterial gel which is sold in the market and contains nano silver or other silver ions; the gel does not cause pain feeling on patients and has relatively strong patient adaptability; and the antibacterial gel can be used for various types of wounds, gynecological diseases and anorectal diseases and can also be matched with traditional wound dressing.

The invention provides an antibacterial non-woven fabric and a preparation method thereof. The preparation method comprises the following steps of firstly, preparing a polyvinylidene fluoride/hydrophilic polyurethane composite fiber non-woven fabric, and then performing electron beam radiation treatment on the composite fiber non-woven fabric; then immersing the composite fiber non-woven fabric into an antibacterial agent ionic liquid for grafting reaction; and finally, performing extracting with methanol and performing vacuum drying to obtain the successfully grafted antibacterial non-woven fabric. According to the preparation method, a polyvinylidene fluoride polymer is taken as a fiber main body, and hydrophilic polyurethane is introduced for composite spinning, so that the mechanical property and the hydrophilic property of the prepared antibacterial non-woven fabric are remarkably improved. By utilizing the grafting reaction of the polyvinylidene fluoride polymer and the antibacterial agent ionic liquid, the prepared antibacterial non-woven fabric is excellent in broad-spectrum antibacterial property, and the sterilizing rate of staphylococcus aureus reaches 99 percent or above.

The invention provides a non-toxic marine ship antifouling coating material, which is prepared from the following raw materials in parts by mass: 100 parts of organic silicon resin, 1 to 3 parts of achitosan quaternary ammonium salt, 5 to 10 parts of fly ash nanoparticles, 0.5 to 1 part of a coupling agent, 3-5 parts of a curing agent, 0.01 to 0.1 part of a catalyst, 0.2 to 0.5 part of an antifoaming agent, and 0.2 to 0.5 part of a leveling agent. According to the invention, organic silicon resin is used as a matrix, nano fly ash is used as a carrier, and a chitosan quaternary ammonium salt loaded on the surface is used as a main antifouling agent, wherein the chitosan quaternary ammonium salt has good solubility and antibacterial property, has biocompatibility, and is safe and non-toxic,the fly ash nanoparticles have strong alkalinity, and the organic silicon is also a low surface energy material; by using a hydrophilic chitosan quaternary ammonium salt as a main antibacterial material, so that the use of a large amount of organic solvents is avoided, the cost is low, and less waste liquid is generated; and fly ash nanoparticles are activated to promote the self-polymerization of organic silicon resin molecules to form a layered structure with certain orientation so as to enhance the strength and elastic modulus of the coating material.

The invention provides a method for efficiently preparing a recombinant antibacterial peptide PaDef in pichia pastoris. The method comprises the following steps: taking pichia pastoris as a host cell, modifying a gene sequence of the antibacterial peptide PaDef (the antibacterial peptide PaDef is named as mPaDef), inserting the antibacterial peptide mPaDef into a pPICZalphaA vector, successfully transferring the vector into pichia pastoris GS115, performing inducible expression with methanol and performing purification and activity identification on an expression product. A final product is a high expression strain of the recombinant antibacterial peptide mPaDef, and the yield of the recombinant antibacterial peptide in supernatant of fermentation liquor is 84mg/L. The prepared recombinant antibacterial peptide has broad-spectrum antibacterial activity and good temperature and protein stability and is comparatively good in stability in weak acid, neutral and alkaline environments.

The invention relates to a production process for dried cattle beef. The production process comprises a raw meat soaking and blood removing step, a raw meat segmenting step, a cropping step, a cutting step, a preparing and frying step, a baking step, a cooling step, a high-temperature sterilizing step, a vacuum packaging step and a storing step. In the steps, the added spice comprises the following raw materials in parts by weight: 10-12 parts of amomum, 10-12 parts of cardamom, 10-12 parts of clove, 10-12 parts of costus root, 10-12 parts of cinnamon, 10-12 parts of amomum tsao-ko, 2-4 parts of rhizoma kaempferiae, 20-22 parts of anise, 20-22 parts of spikenard, 20-22 parts of patchouli, 20-22 parts of sinomenium acutum aroma, 1-3 parts of lithospermum, 1-3 parts of Ricepaperplant Pith , 1-3 parts of lysimachia foenum-graecum, 1-3 parts of licorice root, 10-12 parts of lysimachia sikokiana, 20-22 parts of fennel, 1-3 parts of dried orange peel and 2-4 parts of bay leaf. Compared with the prior art, the production process disclosed by the invention has the advantages the fishy flavor removing and refresh keeping effects can be enhanced, the excellent mouthfeel of the dried cattle beef can be still maintained after the dried cattle beef is stored for six months; and the used spice is lower in cost and natural in components, has a dietary therapy function and anti-oxidation function and benefits the health.

The invention discloses an amorphous carbon-based space antibacterial wear-resistant solid lubricating composite film layer and a preparation method thereof. The composite film layer comprises a base layer, a metal doped amorphous carbon transition layer, an undoped amorphous carbon layer, a first Cu/Ag co-doped amorphous carbon transition layer, a Cu/Ag co-doped amorphous carbon layer, a second Cu/Ag co-doped amorphous carbon transition layer and an undoped amorphous carbon layer which are arranged in sequence. Aiming at the requirements of a space residence cabin environment for an antibacterial lubricating anti-friction coating layer, through the structural design of the coating layer, the base supporting layer, the transition layers, the functional layers and other different layers are matched with one another, and the two antibacterial elements Ag and Cu are compounded and introduced into the coating layer, the coating layer has the anti-friction and wear-resistant characteristics, and meanwhile is resistant to gram-negative bacteria represented by escherichia coli and gram-positive bacteria represented by staphylococcus aureus, and the good broad-spectrum antibacterial property is achieved. The film layer can well improve the antibacterial property and the lubricating property of moving parts of a space station.

The invention provides a preparation method of a medical non-woven fabric composite. The method specifically includes the following steps of firstly, weighing 30-50 parts by weight of adipic acid/polybutylene terephthalate, 20-30 parts by weight of polybutylene terephthalate and 30-40 parts by weight of polycarbonate to be sufficiently mixed to obtain a mixture A; secondly, blending the mixture in the first step with 1-4 parts by weight of antistatic agent and 0.5-2 parts by weight of antibacterial agent, and conducting extruding and granulating through a twin-screw extruder to obtain a blend; thirdly, conducting vacuum drying on the blend in the second step, conducting heating, fusing, extruding, stretching, cooling and self-adhering on the dried blend through a screw extruder to form a non-woven fabric; fourthly, spraying an anti-radiation layer on one side of the non-woven fabric obtained in the third step, and putting the fabric into a drying box to be dried and shaped. The prepared medical non-woven fabric composite has antibacterial performance, radiation prevention performance and antistatic performance and is mainly applied to preparing a medical mask.

The invention discloses a preparation method of a decoration coating material for building construction, and particularly relates to the technical field of decoration coating material preparation. Thedecoration coating material comprises the following raw materials by weight: 100-200 parts of an acrylate aqueous solution, 30-50 parts of titanium dioxide, 40-60 parts of calcium carbonate, 50-60 parts of silica powder, 1-2 parts of hydroxyethyl cellulose, 20-30 parts of quicklime, 6-8 parts of chitosan, 10-20 parts of aloe, 10-20 parts of artemisia argyi and 6-8 parts of ultraviolet-proof powder, wherein the auxiliary materials comprise the following components in parts by weight: 2-4 parts of a defoaming agent, 4-8 parts of a dispersing agent, 2-6 parts of a film aid, 2-4 parts of a preservative, 2-4 parts of an anti-freezing agent and 60-80 parts of water. By adding lime water, chitosan, aloe extracting solution and artemisia argyi extracting solution, the prepared coating material has antibacterial and bactericidal functions, can prevent rot and mildew phenomena, can protect wall surfaces, and is non-toxic and harmless to a human body, safe and environment-friendly.

The invention discloses a zinc germanate matrix sustained-released antibacterial nano material capable of monitoring afterglow light and a preparation method thereof, and belongs to the field of preparation of antibacterial nano materials. The chemical composition general formula of the zinc germanate matrix antibacterial nano material is Zn2GeO4: xM, x is greater than or equal to 0.001 and less than or equal to 0.02, Zn2GeO4 is a matrix, and M is a metal ion with an antibacterial effect. The zinc germanate matrix antibacterial nano material is synthesized by a hydrothermal method, is simple to prepare and low in cost, and can be used for industrial production; the material has excellent broad-spectrum antibacterial performance at a bacterial infection part, metal ion slow release can maintain high antibacterial concentration for a long time, the antibacterial period is long, and the possibility of inducing bacteria to generate drug resistance is extremely low; and in a subacid environment of a bacterial infection part, the afterglow light intensity of the material changes along with degradation of the material, and real-time monitoring of the antibacterial process of the infection part can be realized by utilizing the change of the afterglow intensity.

The invention relates to the technical field of edible packaging materials, in particular to an edible antibacterial film and a preparation method thereof. Raw materials comprise dissolving pulp, a cationic etherifying agent, methyl cellulose, wheat gluten protein, glycerol, lipids and a natural antibacterial agent. Electrostatic repulsion and steric hindrance effects among molecules of the cationic modified cellulose nanofibril are utilized, so that uniform distribution of the nanofibril in an edible film matrix is facilitated, and the nano-sized reinforcing and toughening effects of the nanofibril are brought into full play; by means of the long-acting stable antibacterial effect of the grafted quaternary ammonium salt group and in combination with the addition of the natural quick-acting antibacterial agent, the edible film is endowed with a good antibacterial effect, the shelf life of a packaged product is prolonged, and the product quality is improved; and besides, the selected raw materials are natural edible macromolecular polymers, so that the edible composite film has no toxic or side effect on a human body and is low in cost, dependence and use of petroleum resources arereduced, and the edible composite film is simple in preparation process and convenient to operate, thereby having a relatively good market application prospect.