Low-molecular chitosan @ silver nanoparticle compound film, and preparation method and applications thereof

A low-molecular-weight chitosan and silver nanoparticle technology, applied in the field of material science and engineering, can solve problems such as dispersibility and instability restricting applications, achieve strong antibacterial effect and bacterial retention ability, enhance antibacterial ability and moisture retention , Overcome the effect of poor water solubility

Active Publication Date: 2018-02-16
SOUTH CHINA INST OF COLLABORATIVE INNOVATION
View PDF5 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although nanosilver has excellent antibacterial properti

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Low-molecular chitosan @ silver nanoparticle compound film, and preparation method and applications thereof
  • Low-molecular chitosan @ silver nanoparticle compound film, and preparation method and applications thereof
  • Low-molecular chitosan @ silver nanoparticle compound film, and preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0049] Example 1: Preparation of low molecular chitosan@silver nanoparticle composite membrane material

[0050] Dissolve 4.00g of chitosan in 200mL HAc-NaAc solution with pH=4.5, stir evenly to dissolve it completely, add 0.20g of papain and stir for 11.5 hours at a constant temperature of 45°C, heat up to a constant temperature of 60°C, and then Add 40mL H 2 O 2 The solution was reacted for 30 minutes, heated at 100°C for 5 minutes, and naturally cooled to room temperature. The papain was removed by filtration, and the filtrate was precipitated with 4 times the volume of absolute ethanol to precipitate the product low molecular chitosan, separated by suction, and activated under vacuum for 24 hours to obtain a sample and label this sample as LMWC-1.

[0051] Then, weigh 0.4762g LMWC-1 sample and 9.5238g polyvinyl alcohol into 90mL deionized water, swell for 30 minutes to make it uniformly dispersed, and then add 1mL of 20mg / mL AgNPs dispersion (before use) Ultrasound in an ultra...

Example Embodiment

[0052] Example 2: Preparation of low molecular chitosan@silver nanoparticle composite membrane material

[0053] Dissolve 4.00g of chitosan in 200mL HAc-NaAc with pH=4.5, stir evenly to dissolve it completely, add 0.40g of papain and stir for 11.5 hours at a constant temperature of 45°C, warm up to a constant temperature of 60°C, and add to it Add 40mL H 2 O 2 The solution was reacted for 30 minutes, and the solution was heated in a boiling water bath for 5 minutes, and then cooled to room temperature naturally. The papain was removed by filtration, and the filtrate was precipitated with 4 times the volume of absolute ethanol to precipitate the low-molecular-weight chitosan, separated by suction, and activated under vacuum for 24 hours to obtain a sample and label this sample as LMWC-2. Weigh 0.4762g LMWC-2 sample and 9.5238g polyvinyl alcohol into 90mL deionized water, first swell for 30 minutes to make it uniformly dispersed, and then add 1mL of 20mg / mL AgNPs dispersion to it (...

Example Embodiment

[0054] Example 3: Preparation of low molecular chitosan@silver nanoparticle composite membrane material

[0055] Dissolve 4.00g of chitosan in 200mL HAc-NaAc with pH=4.5, stir evenly to dissolve it completely, add 0.27g of papain and stir for 11.5 hours at a constant temperature of 45°C, warm up to a constant temperature of 60°C, and add to it Add 40mL H 2 O 2 The solution was reacted for 30 minutes, and the solution was heated in a boiling water bath for 5 minutes, and then cooled to room temperature naturally. The papain was removed by filtration, and the filtrate was precipitated with 4 times the volume of absolute ethanol to precipitate the product low molecular chitosan, separated by suction, and activated under vacuum for 24 hours to obtain a sample and label this sample as LMWC-3. Weigh 0.4762g LMWC-3 and 9.5238g polyvinyl alcohol into 90mL deionized water, first swell for 30 minutes to make it evenly dispersed, and then add 1mL of 20mg / mL AgNPs dispersion to it (first use...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention belongs to the technical field of material science and engineering, and discloses a low-molecular chitosan @ silver nanoparticle compound film and a preparation method thereof and applications in the field of antibacteria and anti-corrosion. The preparation method of the invention comprises the following steps: adding enzyme powder into a buffer solution of macromolecular chitosan, conducting reaction with stirring for 10-14h at 30-60 DEG C, adding a H2O2 solution, conducting reaction at 50-80 DEG C for 20-60min, conducting heating for 5-10min at 90-110 DEG C, and conducting pumping filtration, separation, heating and activation to obtain a low-molecular chitosan final product; adding the low-molecular chitosan final product and polyvinyl alcohol into water, conducting uniform mixing, adding an AgNPs dispersion liquid, conducting stirring at 30-90 DEG C for 4-5h, and conducting stirring for 1-2h in a cell pulverizer to obtain an electrostatic spinning solution; and conducting spinning to obtain the low-molecular chitosan @ silver nanoparticle compound film. The compound film of the invention has excellent performance, has stronger antibacterial effects and bacteria interception capability, and can be applied to the fields of the antibacterial and the anti-corrosion.

Description

technical field [0001] The invention belongs to the field of material science and engineering technology, and in particular relates to a low-molecular-weight chitosan@silver nanoparticle composite film, its preparation method and its application in the antibacterial and antiseptic fields. Background technique [0002] With the progress of human beings, people place higher expectations on human health, and the safety standards for daily chemicals are getting higher and higher. As one of the indispensable additives in the daily chemical industry, preservatives have safety standards will also increase. Preservatives are generally divided into synthetic preservatives and natural preservatives. Synthetic preservatives are mostly used now, but long-term studies have found that some synthetic preservatives have problems such as carcinogenicity, teratogenicity, and poisoning. 2009 "Johnson & Johnson Toxic" incident: Johnson & Johnson's baby bathroom products were exposed to contai...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A23L3/3562A23L3/3571A23L3/358A61K8/19A61K8/73A61Q19/00A01N59/16A01N43/16A01N25/08A01N25/12A01P3/00A01P1/00
CPCA01N25/08A01N25/12A01N43/16A01N59/16A23L3/3562A23L3/3571A23L3/358A61K8/19A61K8/736A61K2800/524A61Q19/00
Inventor 程建华余林玲郑华生张鹏
Owner SOUTH CHINA INST OF COLLABORATIVE INNOVATION
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap