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Compound polyhexamethylene biguanide disinfectant and preparation method thereof

A technology of polyhexamethylene biguanide and disinfectant, which is applied in the directions of botanical equipment and methods, disinfectants, pharmaceutical formulations, etc., can solve the problems of complex disinfectant components, high requirements on the content of fungicides, etc., and achieves excellent disinfection effect, The bactericidal effect is mild and the effect that meets the disinfection requirements

Active Publication Date: 2021-02-09
江苏聚锦生物医疗科技有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent 201610340134 discloses a compound quaternary ammonium salt disinfectant, in which hexamethylenetetramine, benzalkonium bromide, benzalkonium chloride, polyhexamethyleneguanidine, octadecyldimethylbenzyl Chloride and Tween 80 are compatible in proportion, and the sterilizing effect is achieved through synergistic effect between the components. However, the composition of the disinfectant is complex, and the content of polyhexamethylene guanidine still needs to be more than 0.5%. Higher content of fungicides

Method used

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  • Compound polyhexamethylene biguanide disinfectant and preparation method thereof
  • Compound polyhexamethylene biguanide disinfectant and preparation method thereof
  • Compound polyhexamethylene biguanide disinfectant and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Composite polyhexamethylene biguanide disinfectant comprises by weight percentage:

[0026] polyhexamethylene biguanide 0.2% citric acid 0.2% Phosphate buffer margin

[0027] Adjust the pH to 6.6.

Embodiment 2

[0029] Composite polyhexamethylene biguanide disinfectant comprises by weight percentage:

[0030] polyhexamethylene biguanide 0.2% citric acid 0.4% Phosphate buffer margin

[0031] Adjust the pH to 6.6.

Embodiment 3

[0033] Composite polyhexamethylene biguanide disinfectant comprises by weight percentage:

[0034] polyhexamethylene biguanide 0.3% citric acid 0.6% Phosphate buffer margin

[0035] Adjust the pH to 6.6.

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Abstract

The invention discloses a compound poly-hexamethylene biguanide disinfectant and a preparation method thereof. The compound poly-hexamethylene biguanide disinfectant comprises the following main ingredients: poly-hexamethylene biguanide and water-soluble polyquaternary salt, and also comprises citric acid, a supplemental additive, a surfactant, a thickening agent, a moisturizing agent, a stabilizer or a pH regulator, wherein the pH value is 6.5-7.0. The compound poly-hexamethylene biguanide disinfectant has the advantages that under the condition of low biguanide content, an effective disinfection effect is achieved, and the surface disinfection requirements of objects can be met, therefore, the compound poly-hexamethylene biguanide disinfectant is suitable for disinfecting and cleaning the surfaces of articles such as medical instruments and the surface of skin.

Description

technical field [0001] The invention belongs to the technical field of disinfectants, and relates to a compound polyhexamethylene biguanide disinfectant and a preparation method thereof. Background technique [0002] The wet wipes for disinfection are easy to use, and can be used not only for cleaning and disinfection of the skin surface, but also for cleaning and disinfection of the surface of objects. At present, commonly used disinfectants for wet wipes are mainly high-concentration alcohols such as ethanol, phenols such as triclosan, etc., quaternary ammonium salts such as benzalkonium chloride, didecyldimethylammonium chloride, etc., and Guanidines such as chlorhexidine acetate and polyhexamethylene biguanide. Although quaternary ammonium salt cationic fungicides have been widely used, as small organic molecules, there are problems such as easy volatilization, poor chemical stability, and slightly greater toxicity and irritation. Chlorhexidine acetate is limited in it...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/785A61K31/194A01N47/44A01N37/36A61P31/02A01P1/00A61P31/04A61P31/10A01P3/00
CPCA01N37/36A01N47/44A61K31/194A61K31/785A61P31/02A61P31/04A61P31/10A61K2300/00
Inventor 曹冰亚
Owner 江苏聚锦生物医疗科技有限责任公司
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