Compound polyhexamethylene biguanide hydrochloride disinfectant and preparation method thereof

Abstract

The invention discloses a compound polyhexamethylene biguanide hydrochloride disinfectant and a preparation method thereof. The disinfectant comprises the following components in percentage by weight:0.1-5% of polyhexamethylene biguanide, not more than 0.1% of glutaraldehyde, 0.3-0.9% of a pH regulator, 0.1-0.5% of a chelating agent, 0.1-0.5% of a stabilizer, 0.1-0.9% of a humectant, 1% of a surfactant and the balance of water. The preparation method comprises the following steps of: firstly, adding polyhexamethylene biguanide into purified water in proportion, performing uniform stirring, then adding glutaraldehyde, and performing stirring; then adding a humectant, then adding a chelating agent, a surfactant and a stabilizer, and fixing the volume; and finally, adding a pH regulator to regulate the pH value to 5.0-6.5. According to the compound polyhexamethylene biguanide hydrochloride disinfectant and the preparation method thereof of the invention, the polyhexamethylene biguanide is used as a main effective component; the mass ratio of the polyhexamethylene biguanide to other auxiliary additives in the disinfectant is controlled, the polyhexamethylene biguanide and the other auxiliary additives can generate a synergistic effect, an effective disinfection effect is achieved under the condition of low biguanide content; the object surface disinfection requirement is met; andthe disinfectant is suitable for disinfection and cleaning of the surfaces of medical instruments and other objects.

Description

technical field [0001] The invention relates to the technical field of disinfectants, and more specifically relates to a compounded polyhexa-salt methyl biguanide hydrochloride disinfectant and a preparation method thereof. Background technique [0002] Polyhexa-salt methyl biguanide is a broad-spectrum antibacterial agent developed by Aveciago Company in the United Kingdom and is recognized as the safest and most efficient broad-spectrum antibacterial agent in the 21st century. After being able to form a layer of cations on the surface of the article to inhibit bacteria for a long time, and will not cause the formation of antibacterial bacteria, its safety has been approved by the US FDA and EPA, and its semi-lethal dose for mice LD50>5000mg / kg , is the actual non-toxic grade. Environmentally friendly polymer bactericidal disinfectant - polyhexa-salt methylguanidine, has a broad spectrum of sterilization; low effective concentration; fast action speed; stable properties...

AI Technical Summary

Problems solved by technology

[0006] In addition to polyhexa-salt methyl biguanide and glutaraldehyde, other disinfectants have common weaknesses such as bleaching and corrosive effects on clothing, etc., are easy to oxidize and are not easy to store, and have certain toxicity and irritation. The environment is also prone to secondary pollution, etc. The compound of polyhexa-salt methyl biguanide and glutaraldehyde can overcome the shortage of disinfectants

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