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Ammonia sugar calcium tablet for increasing bone density and preparation method of tablet

A technology for increasing bone density and glucosamine. It is used in medical preparations with non-active ingredients, medical preparations containing active ingredients, and bone diseases. It can solve problems such as expensive and increase bone formation, promote calcium absorption, and prevent Loss of bone calcium

Inactive Publication Date: 2019-03-01
TIANJIN TROPJOIN HEALTH TECH GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, although the current anti-osteoporosis drugs have certain curative effects, they are generally expensive. Therefore, it is very necessary to find and screen domestic drugs with low price and high efficiency.

Method used

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  • Ammonia sugar calcium tablet for increasing bone density and preparation method of tablet
  • Ammonia sugar calcium tablet for increasing bone density and preparation method of tablet
  • Ammonia sugar calcium tablet for increasing bone density and preparation method of tablet

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Effect test

preparation example Construction

[0030] The specific steps of the method for preparing calcium amino sugar tablets for increasing bone density are as follows:

[0031] S1, crush

[0032] Crush D-glucosamine sulfate potassium salt into powder;

[0033] S2, sieving

[0034] Biological calcium carbonate, D-glucosamine sulfate potassium salt, chondroitin sulfate, Panax notoginseng extract, lactose, sodium carboxymethyl starch, magnesium stearate, respectively, through a 60 mesh sieve, vitamin D 3 Pass a 40-mesh sieve;

[0035] S3, mixed

[0036] Use an equal-volume mixing method to first add vitamin D 3 Mix evenly with the Panax notoginseng extract to obtain mixed powder I. The mixed powder I is then mixed with biological calcium carbonate, D-glucosamine sulfate potassium salt, chondroitin sulfate, lactose and sodium carboxymethyl starch for 30 minutes. Mixed powder

[0037] S4, product production

[0038] Add povidone K30 powder to a 15% povidone K30 solution prepared in 60% ethanol to form an auxiliary material binder;

[0...

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PUM

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Abstract

The invention discloses an ammonia sugar calcium tablet for increasing bone density and a preparation method of the tablet. The ammonia sugar calcium tablet comprises the following components in percentage by mass: 23.12% of biological calcium carbonate, 33.5% of D-glucosamine sulfate potassium chloride, 17% of chondroitin sulfate, 5% of notoginseng extracts, 0.04% of Vitamin D3, and 21.34% of auxiliary materials. The auxiliary materials comprise the following components in percentage by mass: 67.96% of lactose, 2.26% of povidone K302, 5.09% of sodium carboxymethyl starch, and 4.69% of magnesium stearate. The preparation method of the ammonia sugar calcium tablet includes: S1. pulverizing; S2. sieving; S3. mixing; S4. product preparing. The biological calcium carbonate, D-glucosamine sulfate potassium chloride, the chondroitin sulfate, the notoginseng extracts and the vitamin D3 all have the effect of increasing bone density, can be used for health food, is safe to eat, has no incompatibility, and finally achieves the purpose of increasing bone density through the synergistic effect of all raw materials.

Description

Technical field [0001] The invention relates to the field of research and development of calcium tablets for improving osteoporosis, and in particular to a calcium amino sugar tablet for increasing bone density and a preparation method thereof. Background technique [0002] Osteoporosis (OP) is a systemic metabolic bone disease. It is characterized by a decrease in bone mass and the destruction of bone microstructures, which leads to increased bone fragility, fractures easily, and high morbidity and mortality. [0003] According to my country’s "Ninth Five-Year Plan" project, an epidemiological study of 48,615 people in my country’s five administrative regions (including 7182 people using DNA to measure the bone mineral density of the lumbar spine and femur) showed that OP and osteopenia (OPA) in people over 40 The prevalence rates were 19.9% ​​and 32.4% for women, and 11.5% and 45.8% for men. The prevalence rates of OP and OPA in people over 60 years old were 28.6% and 13.8% for w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K9/20A61K47/36A61K47/32A61K47/26A61P19/10A61K31/593A61K31/7008A61K31/737A61K33/10
CPCA61K9/2018A61K9/2027A61K9/2059A61K31/593A61K31/7008A61K31/737A61K33/10A61K36/258A61P19/10A61K2300/00
Inventor 许强
Owner TIANJIN TROPJOIN HEALTH TECH GRP
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