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Traditional Chinese medicine peptide for treating chicken coccidiosis and preparation method thereof

A technology of chicken coccidiosis and traditional Chinese medicine, which is applied in the direction of medical formula, medical preparations containing active ingredients, anti-infective drugs, etc., can solve the problems of slow effect, meat and egg drug residue, long treatment cycle, etc., and achieve narrow distribution , small molecular weight, no toxic side effects

Inactive Publication Date: 2019-03-08
河北肽都生物科技集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the problems that existing traditional Chinese medicines treat chicken coccidiosis with slow effect and long treatment cycle, and western medicines treat meat and eggs with drug residues, the present invention provides a traditional Chinese medicine peptide for treating chicken coccidiosis

Method used

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  • Traditional Chinese medicine peptide for treating chicken coccidiosis and preparation method thereof

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Embodiment 1

[0032] The embodiment of the present invention provides a traditional Chinese medicine peptide for treating coccidiosis in chickens, which includes the following raw materials in proportions by weight: Pulsatilla: 5 parts, Dandelion: 7 parts, Peony: 4 parts, Astragalus: 3 parts, Garlic: 4 parts , 2 parts of Scutellaria baicalensis.

[0033] The preparation method of the above-mentioned traditional Chinese medicine peptide for the treatment of chicken coccidiosis comprises the following steps:

[0034] Step a: Add 500g of Pulsatilla radix, 700g of dandelion, 400g of peony, 300g of astragalus, and 200g of baicalin, add 17.5L of purified water and stir evenly, decoct at 90°C for 7h, then add 400g of garlic, and continue decocting for 0.5h ;

[0035] Step b. Cool the decoction liquid obtained in step a to 56°C, add 25g of Aspergillus niger amylase and 25g of Aspergillus oryzae neutral protease for enzymolysis, after the end of the enzymolysis, raise the temperature to 90°C and ke...

Embodiment 2

[0038] The embodiment of the present invention provides a traditional Chinese medicine peptide for treating coccidiosis in chickens, which includes the following raw materials in proportions by weight: Pulsatilla: 10 parts, Dandelion: 8 parts, Peony: 6 parts, Astragalus: 6 parts, Garlic: 6 parts , Scutellaria baicalensis: 4 parts.

[0039] The preparation method of the above-mentioned traditional Chinese medicine peptide for the treatment of chicken coccidiosis comprises the following steps:

[0040] Step a. Add 10Kg of Pulsatilla radix, 8Kg of dandelion, 6Kg of peony, 6Kg of astragalus, and 4Kg of scutellaria baicalensis, add 300L of purified water and stir evenly, decoct at 92°C for 7.5h, then add 6Kg of garlic, and continue decocting for 0.75h ;

[0041] Step b. Cool the decoction liquid obtained in step a to 57°C, add 500g of Aspergillus niger amylase and 500g of Aspergillus oryzae neutral protease for enzymolysis, after the end of the enzymolysis, raise the temperature t...

Embodiment 3

[0044]The embodiment of the present invention provides a traditional Chinese medicine peptide for the treatment of coccidiosis in chickens, including the following raw materials in proportions by weight: Pulsatilla: 15 parts, Dandelion: 11 parts, Peony: 8 parts, Astragalus: 7 parts, Garlic: 9 parts , Scutellaria baicalensis: 5 parts.

[0045] The preparation method of the above-mentioned traditional Chinese medicine peptide for the treatment of chicken coccidiosis comprises the following steps:

[0046] Step a, add 15Kg of Pulsatilla chinensis, 11Kg of dandelion, 8Kg of peony, 7Kg of astragalus, and 5Kg of scutellaria baicalensis, add 440L of purified water, stir evenly, and cook at 95°C for 8h, then add 9Kg of garlic, and continue to cook for 1h;

[0047] Step b. Cool the decoction liquid obtained in step a to 58°C, add 825g of Aspergillus niger amylase and 825g of Aspergillus oryzae neutral protease for enzymolysis, after the end of the enzymolysis, raise the temperature to ...

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Abstract

The invention relates to the technical field of veterinary medicine processing, and concretely discloses traditional Chinese medicine peptide for treating chicken coccidiosis and a preparation methodthereof. The traditional Chinese medicine peptide is prepared from the following raw materials in parts by weight through enzymolysis: 5 to 15 parts of radix pulsatillae, 4 to 12 parts of herba taraxaci, 3 to 9 parts of peony root, 3 to 9 parts of radix astragali, 3 to 9 parts of garlics and 2 to 6 parts of radix scutellariae. The preparation method at least comprises the following steps that theraw materials are weighed according to the weight parts; purified water is added for decoction; the temperature of obtained decoction liquid is lowered to 56 to 58 DEG C; amylase and neutral proteaseare added for enzymolysis; after the enzymolysis is finished, enzyme deactivation is performed; enzymolysis liquid is obtained, wherein the enzymolysis time is 3 to 4h; the enzymolysis liquid is separated, purified and dried to obtain the traditional Chinese medicine peptide for treating chicken coccidiosis. The traditional Chinese medicine peptide provided by the invention is favorable for chicken group disease elimination, chicken group growth and egg laying capability improvement; chicken cannot easily generate medicine resistance; no residue exists; the cure rate reaches up to 95 percent or higher.

Description

technical field [0001] The invention relates to the technical field of veterinary medicine processing, in particular to a traditional Chinese medicine peptide for treating chicken coccidiosis and a preparation method thereof. Background technique [0002] Chicken coccidiosis is a common and very serious parasitic disease in chickens. It is an acute epidemic parasitic disease caused by one or more coccidiosis, and it is also the main cause of chicken enteritis. The economic loss it causes in the breeding industry is very large, and the morbidity and lethality rate of 10-30 day-old chicks or 35-60-day-old young chickens can be as high as 80%. The growth of the sick chicks is hindered, and the weight gain is slow; the adult chickens generally do not get sick, but they are carriers, and the weight gain and egg production ability are reduced, which is an important source of spreading coccidiosis. The symptoms are depression of sick chickens, fluffy feathers, curled head, loss of...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P33/02
CPCA61K36/288A61K36/481A61K36/539A61K36/65A61K36/71A61K36/8962A61K2236/19A61K2236/331A61P33/02A61K2300/00
Inventor 张晓东杨广杨子丰
Owner 河北肽都生物科技集团有限公司
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