Plant bacteriostatic skin-care nano-emulsion and preparation method thereof

A nanoemulsion, plant-based technology, applied in the field of biomedicine, can solve the problems of needing to be improved, low bioavailability, poor solubility, etc., to improve bioavailability and water solubility, simple preparation process, and good stability Effect

Active Publication Date: 2021-12-07
BEIJING UNIV OF CHEM TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effect of botanical medicines that are convenient for skin infections needs to be improved
On the one hand, there is no particularly outstanding effect in terms of formula.

Method used

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  • Plant bacteriostatic skin-care nano-emulsion and preparation method thereof
  • Plant bacteriostatic skin-care nano-emulsion and preparation method thereof
  • Plant bacteriostatic skin-care nano-emulsion and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0022] Example 1

[0023] Antibacterial Skin nanoemulsion one kind of plant, plant prepared by the antibacterial component, emulsifier and water together, wherein the components and their proportion of vegetable antibacterial nanoemulsion in the percentages by weight are: 1% lemongrass oil, citrus oil 1%, 1% lavender essential oil, peppermint essential oil 1%, licorice extract 0.5%, 0.5% polylysine, berberine 0.5%, 0.5% matrine, tanshinone 0.5 %. Lemongrass oil, citrus oils, lavender essential oil, peppermint essential oil used were purchased from Beijing fragrant flowers dependents Technology Co., polylysine (molecular weight less than 5000) and Tan purchased from Shanghai Biochemical Technology Co., McLean, Berberis base and matrine purchased from Shaanxi Bai Wei biological Technology Co., licorice extract is dried over anhydrous ethanol for 20h licorice extract obtained. Preparation method:

[0024] Sl, Tween 80 emulsifier, polyglycerol myristate 10-, 10- polyglycerol monolaura...

Example Embodiment

[0033] Example 2

[0034] Antibacterial Skin nanoemulsion one kind of plant, plant prepared by the antibacterial component, emulsifier and water together, wherein the components and their proportion of vegetable antibacterial nanoemulsion in the percentages by weight are: lemongrass oil 1.5%, 1.5% citrus essential oil, lavender essential oil 1.5%, 1.5% peppermint oil, licorice extract 0.5%, 1% polylysine, berberine 1% 1% matrine, tanshinone 1 %. Preparation method:

[0035] Sl, Tween 80 emulsifier, polyglycerol myristate 10-, 10- polyglycerol monolaurate dissolved by heating to form an emulsion;

[0036] S2, the lemongrass oil, citrus oil, lavender oil, peppermint oil, licorice extract, tanshinone emulsifier is added to the solution as an oil phase;

[0037] S3, dissolve the alkali, multi-lysine, berberine in deionized water as aqueous phase;

[0038] S4, add the aqueous phase into the oil phase and form a crude emulsion under high speed shear;

[0039] S5, the obtained crude emul...

Example Embodiment

[0044] Example 3

[0045] Antibacterial Skin nanoemulsion one kind of plant, plant prepared by the antibacterial component, emulsifier and water together, wherein the components and their proportion of vegetable antibacterial nanoemulsion in the percentages by weight are: lemon grass oil 2%, 1% orange essential oil, lavender essential oil 1%, 1% peppermint oil, licorice extract 0.5%, 0.5% polylysine, berberine 0.5%, 0.5% matrine, tanshinone 0.5 %. Preparation method:

[0046]Sl, Tween 80 emulsifier, polyglycerol myristate 10-, 10- polyglycerol monolaurate dissolved by heating to form an emulsion;

[0047] S2, the lemongrass oil, citrus oil, lavender oil, peppermint oil, licorice extract, tanshinone emulsifier is added to the solution as an oil phase;

[0048] S3, dissolve the alkali, multi-lysine, berberine in deionized water as aqueous phase;

[0049] S4, add the aqueous phase into the oil phase and form a crude emulsion under high speed shear;

[0050] S5, the obtained crude emu...

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Abstract

The invention discloses a plant bacteriostatic skin-care nano-emulsion and a preparation method thereof. The plant bacteriostatic skin-care nano-emulsion is prepared from a plant bacteriostatic component, an emulsifier and water, wherein the plant bacteriostatic component comprises the following components in percentage by weight in the nano-emulsion: 1%-2% of lemon citronella oil, 1%-2% of citrus essential oil, 1%-1.5% of lavender essential oil, 1%-1.5% of mint essential oil, 0.5% of a liquorice root extract, 0.5%-1% of polylysine, 0.5%-1% of berberine, 0.5%-1% of matrine and 0.5%-1% of tanshinone. The preparation method of the nano-emulsion comprises the following steps: heating the emulsifier for dissolving to form an emulsion; adding a fat-soluble component in the bacteriostatic component into the emulsion to serve as an oil phase; dissolving a water-soluble component in the bacteriostatic component into deionized water to serve as a water phase; and adding the water phase into the oil phase, forming a coarse emulsion under a high-speed shearing machine, and performing homogenizing at high pressure to obtain the plant bacteriostatic skin-care nano-emulsion.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and relates to a compounding of various plant functional factors and a preparation method of an embedding carrier, in particular to a plant antibacterial skin care nanoemulsion and a preparation method thereof. Background technique [0002] As the body's first line of defense, the skin is always resisting various bacterial and fungal infections from the outside world. Under normal circumstances, antibiotics can be used to control skin infections in the treatment of skin infections: (1) Mupirocin: For skin infections caused by Staphylococcus, Streptococcus, Escherichia coli, Haemophilus influenzae, Neisseria gonorrhoeae, etc. (2) Fusidic acid: mainly used for antibacterial treatment of streptococcus, enterococcus, diphtheria bacillus, clostridium, Neisseria, etc., for pneumonia, Osteomyelitis, sepsis and other serious diseases have a certain relieving effect; (3) Quinolones: This type of anti...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/92A61K8/88A61K8/49A61K8/06A61Q19/00A61Q17/00
CPCA61K8/9789A61K8/922A61K8/88A61K8/49A61K8/4973A61K8/4926A61K8/068A61K8/062A61Q19/00A61Q17/005A61K2800/413A61K2800/5922A61K2800/262A61K2800/805Y02A50/30
Inventor 梁浩康志伟周延
Owner BEIJING UNIV OF CHEM TECH
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