35results about How to "Ensure biosecurity" patented technology

The utility model provides a pig farm reclaimed water recycling system with multiple application scenes, which comprises a pretreatment device, a reverse osmosis device, a first recycling device, a disinfection device and a second recycling device which are connected in sequence, the pretreatment device comprises a full-automatic multi-medium filter and an ultrafilter which are connected in sequence; the reverse osmosis device comprises a scale inhibitor, a precision filter and a reverse osmosis membrane assembly which are connected in sequence, and the ultrafilter is connected with the scale inhibitor; the first recycling device comprises a first water storage tank, and the first water storage tank is connected with the reverse osmosis membrane assembly. The utility model overcomes the key core problem of hindering the reuse of reclaimed water in a large-scale farm, provides a feasible technical scheme for the industry, and not only can relieve the water pressure of the pig farm, but also can save clean water resources.

The invention relates to a repetitive structural unit recombinant protein cpE2 and a preparation method and application thereof. The recombinant protein cpE2 of the repetitive structural unit has self-assembly performance and is formed by modifying an E2 subunit of a pyruvate dehydrogenase compound and dihydrofatty acid amide transacetylase. Specifically, the C end of the E2 protein is arranged at the N end through a connecting peptide by utilizing a circulating recombination principle, so that the recombinant protein cpE2 is constructed. The engineered cpE2 protein cage can be self-assembled into a cage-shaped structure, linking groups can be respectively brought into the protein cage through N-terminal or C-terminal modification of cpE2, the problem that a modifier or a drug is difficult to put into the protein cage by a traditional E2 protein is solved, meanwhile, the specific particle size of the cpE2 protein cage can be controlled through the length of a linking peptide, and the protein cage has a good application prospect. And efficient carrying of goods is achieved.

The invention relates to a silk fibroin hard material, a preparation method and application, and the preparation method comprises the following steps: carrying out bubble removal treatment on a solution containing regenerated silk fibroin to obtain a high-purity silk fibroin solution or a silk fibroin / gelatin composite solution; and performing gel treatment on the high-purity silk fibroin solution or the silk fibroin / gelatin composite solution to obtain the silk fibroin hard material. The method has the advantages that the prepared silk fibroin solution has extremely high purity through the steps of fine degumming, washing, dissolving, dialysis and concentration and the treatment of centrifugal bubble removal.

The invention discloses combined protein nanoparticles based on porcine circovirus type 2 as well as preparation and application of the combined protein nanoparticles. The combined protein nano-particle is formed by self-assembly of an RBD (Radial Basis Description)-Spatier fusion protein and a PCV2 (Poly Carbonaceous V2)-Spytag nano-particle. The combined protein nano-particle based on the porcine circovirus type 2 can generate a high-level RBD specific antibody earlier, and compared with an RBD monomer, the combined protein nano-particle based on the porcine circovirus type 2 can induce generation of a higher-level RBD specific IgG2a antibody and a same-level and same-RBD specific IgG1 antibody. Meanwhile, the level of the combined protein nanoparticles based on the porcine circovirus type 2 for generating neutralizing antibodies is highly consistent with that of wild PCV2 nanoparticles, and the immunogenicity of the PCV2 is not influenced. The combined protein nanoparticles based on the porcine circovirus type 2 can prevent infection of PCV2 and PEDV viruses at the same time, and time and cost of secondary vaccination are avoided.

The invention relates to a ventilation and air-conditioning on-duty energy-saving operation control system and a control mode for a high-grade biosafety laboratory, an air supply system is communicated with the laboratory through an air supply pipeline, the laboratory is communicated with an exhaust system through an exhaust pipeline, and the laboratory is in an absolute negative pressure state; a certain pressure gradient is arranged between every two adjacent rooms of the laboratory to guarantee the directional airflow direction, a first air feeder and a second air feeder are arranged in the air supply system side by side and are standby for each other, a first exhaust fan and a second exhaust fan are arranged in the exhaust system in parallel and are standby for each other, and a first biological safety closed valve is arranged at the inlet end of an air supply pipeline. An air supply closed valve and an air supply variable air volume valve are sequentially arranged at the outlet end of the air supply pipeline, a second biological safety closed valve is arranged at the outlet end of the air exhaust pipeline, and an air exhaust closed valve and an air exhaust variable air volume valve are sequentially arranged at the inlet end of the air exhaust pipeline. The energy consumption is optimized, and the biological safety in a laboratory is ensured.

The invention belongs to the technical field of biology, and relates to a bronchoalveolar lavage fluid (BALF) preserving fluid, a kit and a cytological test method. The preservation solution is composed of TCEP, N-acetylcysteine, EDTA.2Na, trehalose, Proclin300, methanol, sodium chloride and HEPES, and all the components have a synergistic effect to achieve sample viscosity removal, oxidation resistance, corrosion prevention, cell protection and pH stabilization. The preserving fluid is suitable for morphological observation and nucleic acid detection of BALF cells, and can stably preserve samples at room temperature and maintain completeness of cell membranes and clear morphological structure. The kit comprises two preparations which are mixed to form a working solution, and the working solution can be directly used for sample preservation on a sampling site. The cytological test method comprises the steps of sample collection, preservation, centrifugal slide preparation, Wright-Giemsa staining and microscopic observation. Experimental results show that preservation solutions of different formulas are compatible with a chromosome system, the cell morphology is kept stable within 3 days, the dyeing effect is good, and it is proved that the preservation system can remarkably improve the preservation stability and detection reliability of BALF samples and is suitable for cytology and molecular diagnosis application of lower respiratory diseases.

The invention discloses an enzyme preparation for degrading allergens of pet food and application of the enzyme preparation, the enzyme preparation is a pH-responsive acrylic resin-pectin composite double-response shell embedded enzyme-probiotic composite system, a core layer is heat-resistant neutral protease, and a middle layer is a compound of lactobacillus reuteri and bacillus subtilis. In the processing stage, the protease degrades macromolecular allergens, the composite shell in the gastrointestinal environment firstly triggers outer acrylic resin to be dissolved through weak alkalinity of the intestinal tract, then inner pectin is degraded by pancreatin, and probiotics are accurately released to metabolize residual sensitizing peptides. The enzyme preparation realizes full-chain desensitization, is high in survival rate of probiotics, is suitable for various pet foods, and is stable and reliable in desensitization effect.

The utility model relates to a kind of adipose tissue preparation devices, belong to adipose tissue preparation technical field, including outer tube, outer tube upper end sealing connection upper end cover, outer tube lower end sealing connection lower end cover, upper end cover, lower end cover and outer tube are jointly surrounded to form cavity;Outer tube center is set through center shaft assembly;Turbine blade is rotationally set on center shaft assembly, and turbine blade is located in cavity;The utility model only processes adipose tissue by mechanical shearing, avoids the damage of chemical substance to adipose tissue biological activity, guarantees the biological safety of transplant tissue;Rely on manually pushing and pulling center shaft assembly, drive turbine blade to rotate under the resistance of component in cavity, without power or other power source, simple structure, small and exquisite, convenient to carry and operate;Shear stress generated by turbine blade rotation is even controllable, can stably and quickly break adipose tissue, and the broken efficiency is high, and particle size uniformity is good, meet the requirement of clinical transplantation injection.

The utility model discloses a portable isothermal amplification nucleic acid detection bag based on phase change heat release, which relates to the field of isothermal amplification nucleic acid detection, and comprises a phase change material mounting bag 101, and a heat conduction main reaction cabin, an enzyme-free water mounting bag and a flow measurement chromatography test strip mounting cabin which are arranged on the phase change material mounting bag 101, a first weak sealing strip is arranged on the enzyme-free water installation bag, an outlet of the heat conduction main reaction cabin is communicated with an inlet of the infusion apparatus, an outlet of the infusion apparatus is communicated with a liquid inlet of the flow measurement chromatography test strip installation cabin, and a second weak sealing strip is arranged on the infusion apparatus. The problems that a current isothermal amplification nucleic acid detection device is complex in structure and high in cost are solved, and instrument-free reaction and result visualization functions aiming at portable isothermal amplification reaction can be achieved.

The application belongs to the field of agricultural pest prevention and control and the field of pesticides, and provides a method for preventing and controlling spider mites by using bifenthrin-ethomec and plant essential oil, which comprises the following steps: (1) applying a plant essential oil solution or suspension to crops in need of prevention and control; and (2) applying a bifenthrin-ethomec suspension concentrate to the crops in need of prevention and control 12-36 hours after the application of the plant essential oil solution or suspension. According to the method, a low concentration of plant essential oil is applied in advance before the application of bifenthrin-ethomec, so that the dilution multiple of bifenthrin-ethomec can be greatly increased while the prevention and control effect is maintained.

The application discloses a kind of biocompatible materials and preparation method for bionic porous intervertebral fusion cage, belong to intervertebral fusion cage material technical field.A kind of biocompatible materials for bionic porous intervertebral fusion cage, by weight parts includes the following components: polyether ether ketone 65-80 parts, modified functional filler 15-25 parts, hydroxyapatite 8-12 parts, flow modifier 0.5-1 part;The modified functional filler is graphene oxide coated modified barium titanate functional filler.By introducing surface conductive modified nano piezoelectric ceramic particles, realize the effective conversion and transmission of mechanical stimulation to bioelectric signal, this microstructure design makes the insulating polyether ether ketone matrix possess the electric activity of simulating natural bone stress-electric signal response mechanism, so as to be favorable to activate osteoblast activity and promote bone integration of implant interface.

The present invention discloses a non-toxic treatment method for blood-sucking leech bait, comprising the steps of ultrasonic treatment of blood, dilution, pH adjustment, temperature increase, rapid detoxification of small molecular hydroxyl groups and oxygen atoms and ozone-rich water without residue, decomposition of ozone and other strong oxidizing substances by reducing agent, etc. The present invention also provides an application method of the blood-sucking leech bait. The treatment method of the present invention not only ensures that the bait nutrition is not lost and the biological safety is prevented, and the infection epidemic or metabolic imbalance death of leeches after feeding is avoided, but also ensures the quality and safety of leeches as important Chinese medicinal materials. Rapid non-toxic treatment is carried out by screening and adding reducing agents, so as to achieve rapid decomposition and reduction of ozone and other strong oxidizing substances. There are no chemical disinfectants and antibiotic drugs in the whole treatment process, no toxic side effects, no residue, which conforms to the green and healthy breeding concept that the country currently vigorously advocates and encourages to develop, is conducive to improving the overall quality of the medical blood-sucking leech breeding market, and has a strong prospect for promotion and application.

The invention belongs to the technical field of biology, and relates to a construction method and application of a mouse exogenous gene expression model based on an adenovirus vector. The exogenous gene is delivered through the adenovirus vector, the exogenous gene is subjected to site-specific integration to the specific site of the mouse target cell by using the double recombinase, the efficiency is high, the integration site and copy number are controllable, the safety is good, various function acquired variations can be efficiently modeled, and the method can be applied to establishment of a tumor model and research of precision medical treatment.

The present application relates to the technical field of medical packaging materials, and provides a wet non-woven fabric-based medical sterilization packaging composite material and a preparation method thereof, which comprises a wet non-woven fabric layer subjected to densification and reinforcement treatment, a heat-sealing film layer, and an adhesive layer arranged between the two layers, wherein the adhesive layer is distributed in a non-continuous pattern to locally composite the wet non-woven fabric layer and the heat-sealing film layer. Through the synergistic design of densification reinforcement and local composite in a non-continuous pattern, the present application reduces the shedding rate while retaining the air permeation channels in the un-composite area, solves the contradiction between high density and high air permeability, and effectively disperses stress through discrete adhesive structures, thereby realizing the unity of low shedding, high air permeability and stable peeling strength.

This invention discloses a traceable hydrogel for cartilage repair and its applications. The hydrogel, composed of chitosan, sericin, and collagen, forms a three-dimensional biomimetic network, within which a magnetic material is uniformly dispersed. The magnetic material is selected from nano-Fe3O4 or γ-Fe2O3. Addressing the shortcomings of existing hydrogels, such as insufficient mechanical strength, inability to perform non-invasive tracking, easy aggregation of magnetic nanoparticles, and safety risks associated with chemical cross-linking, the traceable hydrogel prepared by this invention can improve the compressive modulus of the hydrogel, promote the deposition of cartilage-specific matrix, and simultaneously retain the complete magnetic signal activity while avoiding the toxicity of chemical cross-linking. The hydrogel can rapidly gel at physiological body temperature, making it suitable for minimally invasive clinical injection, providing a new solution for cartilage defect repair that combines functionality and safety.

The invention discloses an efficient PCV2 virus proliferation and purification system which comprises a linear actuator integrated operation table, a linear actuator is fixedly installed on a bearing platform of the integrated operation table, a mechanical arm is fixedly installed on a sliding platform of the linear actuator, and the mechanical arm is located between hidden machine covers of two hidden protectors. Hidden machine covers of the two hidden protectors are fixedly installed on a bearing platform of the integrated operation table in a mirror symmetry mode, and proliferation equipment or purification equipment is fixedly installed in the two hidden protectors respectively. Efficient control and biological safety measures are integrated, and through cooperative work of the linear actuator and the operation table, the grabbing efficiency of the mechanical arm is greatly improved, and manual intervention is reduced. And the hidden protector closes the equipment, so that the biological safety is guaranteed, and virus leakage is prevented. The cavity design optimizes resource management and reduces waste liquid pollution. Modular equipment is convenient to maintain, the flexibility and adaptability of the system are enhanced, and various experiment requirements are met.

The invention belongs to the technical field of biological medicine, and relates to a BODIPY-based photosensitizer compounded platinum complex, a preparation method and application thereof, the BODIPY-based photosensitizer compounded platinum complex comprises a cis-platinum complex c-BBP or a counter-platinum complex t-BBP, the molecular formula of the cis-platinum complex c-BBP and the counter-platinum complex t-BBP is C36H42B2F4N8Pt, the molecular formula of the counter-platinum complex c-BBP is C36H42B2F4N8Pt, and the molecular formula of the counter-platinum complex t-BBP is C36H42B2F4N8Pt. The platinum complex is combined with a BODIPY photosensitizer and combined with PDT, the defects of platinum drugs are effectively overcome, the complex has an inhibiting effect on tumor cells, and a new direction is provided for development of new anti-cancer drugs.

The invention discloses an integrated patch for wound pH detection and nitric oxide gas treatment and a preparation method of the integrated patch, relates to a biomedical engineering device, and is used for pH monitoring and nitric oxide (NO) treatment at a wound. According to the system, the pH value of a wound is monitored in real time by adopting a colorimetric method, and a micro light-emitting diode (LED) is used as a switch to control the release of nitric oxide, so that slow-release treatment of low-concentration nitric oxide can be realized, and sterilization treatment can be performed under a high-concentration condition. The patch specifically comprises a flexible circuit and a PVA film, and wireless gas therapy is realized through light by fixing an NO donor in the PVA film. According to the invention, ultrasonic energy can be collected in a living body and is converted into an electric signal based on a piezoelectric effect, so that wireless energy supply is realized. According to the invention, slow release and rapid release of NO can be realized, and different requirements in medical scenes can be realized.

This invention belongs to the field of animal disease prevention and control technology, and discloses a method and system for risk analysis of cross-regional transmission of brucellosis in livestock. The method includes: constructing a spatiotemporal dataset of all transmission vectors and dividing it into risk units; determining an initial risk value; constructing hierarchical risk transmission rules based on the spatiotemporal activity characteristics of each transmission vector; using risk units with initial risk values ​​exceeding a preset threshold as disturbance sources, calculating the basic risk input quantity according to the hierarchical risk transmission rules; determining whether there are at least two types of risk inputs within the same time window of the same risk unit, and processing the basic risk input quantity to obtain an initial transmission risk value; and correcting the initial transmission risk value by combining an active blocking coefficient and a passive attenuation factor to obtain a comprehensive actual transmission risk value, and classifying the risk level and identifying the risk type to generate the transmission risk results for each risk unit. This invention enhances the practical support capability for risk analysis of cross-regional transmission of brucellosis in livestock.

The utility model provides a bacterial liquid spraying device for manufacturing a mouse skin bacterial infection model, which comprises a fixed cylinder and two support rods, a through groove is arranged at the top of the fixed cylinder, a mounting groove is arranged at the front end of the through groove at the top of the fixed cylinder, a fixing mechanism is arranged in the fixed cylinder, sliding grooves are arranged at the top of the fixed cylinder on both sides of the through groove, and the sliding grooves are communicated with the through groove. Mounting plates are fixedly connected to the two ends of the top of the fixed cylinder, a motor is fixedly mounted on one side of the mounting plate at one end, a moving mechanism is arranged between the two mounting plates, and limiting mechanisms are arranged on the portions, on the two sides of the moving mechanism, between the two mounting plates. And then a moving block is driven to move, so that the moving block drives an adjusting plate below to move from the tail of the nude mouse to the head of the nude mouse, and uniform spraying is performed on the skin of the nude mouse through a through groove by utilizing a bacterial liquid spray head, so that the accuracy and repeatability of a research result are better, and the biological safety is better guaranteed.

The invention provides a C type lectin protein nanoparticle based on African swine fever virus, a fusion protein, and preparation and application of the C type lectin protein nanoparticle and the fusion protein. According to the present invention, Ferritin nanoparticles inserted with a Spytag label are adopted as an exogenous antigen display carrier, covalent linkage is performed on the Ferritin nanoparticles and a recombinant protein obtained after fusion of an African swine fever virus C type lectin extracellular domain and a Spypatcher, and the linked nanoparticles are successfully purified by means of gel chromatography and the like; in animal immune evaluation experiments, it is found that after the C type lectin extracellular domain is connected with the Ferritin nano-particles, the level of a C type lectin specific antibody in an organism is obviously improved, and the T cell immune response of the organism can be increased.

The invention discloses a nanoparticle-based plant living body nucleic acid efficient delivery method and application, and belongs to the technical field of biology and the field of agriculture. The functional nucleic acid and a salt compound required by plant growth are self-assembled to form carrier-free nano-particles, then the carrier-free nano-particles and a plant living body are co-incubated and cultured, and plant living body cells actively take in the carrier-free nano-particles, so that the functional nucleic acid is efficiently delivered into the plant living body. The carrier-free nanoparticles prepared by the invention contain functional nucleic acid and salt compounds, and have the advantages of simple preparation process, low cost, good biological safety and the like. In addition, delivery steps are simple and convenient, the method is suitable for various plant species and plant cells in different development stages, and non-destructive efficient gene delivery can be achieved. The technology not only effectively improves the efficiency and convenience of plant gene delivery, but also provides reliable support for application of plant genetic improvement tools, precision agriculture and the like, and has remarkable application prospects and market potential.

The invention discloses a preparation method of a degradable biological magnesium alloy material for promoting bone healing, and relates to the technical field of magnesium alloy materials.The preparation method comprises the following steps of smelting, homogenizing, rolling, laser cladding and accumulative ply rolling, the phase composition of the biological magnesium alloy is of a complete solid solution structure, and the biological magnesium alloy can be completely degraded in a living body; the biological magnesium alloy material has the advantages that the biological magnesium alloy material can be degraded, second-phase particles difficult to dissolve are not generated in the degradation process, the biological safety is guaranteed, the antibacterial effect can be achieved by adding a small amount of Ag element and releasing Ag ions in the in-vivo service process, the forming performance of the biological magnesium alloy material is guaranteed by adopting rolling and accumulative ply rolling, a foundation is laid for subsequent preparation of implantation devices, and the service life of the biological magnesium alloy material is prolonged. And the mechanical property of the alloy is remarkably improved through plastic deformation. By adopting the laser cladding, the fusion and re-solidification of the hydroxyapatite powder and the surface layer of the biological magnesium alloy are realized, the particles are not easy to aggregate in the subsequent accumulative ply rolling, and the uniform distribution of the hydroxyapatite powder in the subsequently prepared biological magnesium alloy material is ensured.

This invention discloses a vehicle cleaning device for livestock farms. The device includes a ramp, a cleaning canopy installed on the ramp, a water guide frame installed on the ramp, water guide side barriers on both sides of the ramp, a groove in the center of the ramp, an even number of movable guide rails installed in the groove, a cleaning device installed on the even number of movable guide rails, and a cleaning drive installed at the top of the ramp. The cleaning canopy contains a canopy body, with lifting seats fixed to the outer walls on both sides. This invention, by creating a groove in the center of the ramp, allows vehicles to complete exterior cleaning with the assistance of the cleaning canopy and then stop. Subsequently, the cleaning drive activates, causing the movable guide rails to assist in the displacement of the cleaning device's platform. Simultaneously, fan-shaped sprayers clean the hidden parts of the vehicle's underside, while movable spray components on both sides repeatedly wash the inside of the vehicle and the wastewater generated during cleaning. Ultimately, this method is not limited by the terrain of the ramp and effectively ensures biosecurity in the livestock area.

The invention discloses preparation and application of a hyperbranched polymer with high gene transfection capacity, and belongs to the technical field of chemical synthesis and modification. The preparation method of the hyperbranched polymer with high gene transfection capacity comprises the following steps: adding an acrylate compound and organic amine into an organic solvent, dissolving, carrying out addition reaction, cooling, adding an end-capping reagent, and continuously reacting to obtain the hyperbranched polymer. The hyperbranched polymer prepared by the invention can solve the problem that the transfection efficiency is low after the existing precursor is polymerized, the transfection capacity of nucleic acid drugs in cells is remarkably improved while the biological safety is ensured, and the hyperbranched polymer is expected to replace viral vectors to be used as mainstream nucleic acid drug delivery vectors in the market.

The invention discloses a vehicle risk avoiding method, system and device and a computer readable storage medium, and relates to the technical field of vehicle control, and the method comprises the steps: predicting whether a first vehicle collides with a target vehicle after emergency braking or not; in response to the fact that the first vehicle is predicted to collide with the target vehicle after emergency braking, obtaining information about whether organisms exist or not of a second vehicle in front of the target vehicle; information about whether organisms exist in a first lane section is obtained, the first lane section comprises road sections, corresponding to the target vehicle and a second vehicle, on a second lane, and the second lane is adjacent to the first lane; according to the biological existence information of the second vehicle and the biological existence information of the first lane section, an initial risk avoiding strategy of the target vehicle is determined, and the initial risk avoiding strategy comprises a strategy for preventing the target vehicle from colliding with the biological substances; determining a target risk avoiding strategy according to the initial risk avoiding strategy; and controlling the target vehicle to avoid risks according to the target risk avoiding strategy. The target vehicle can be prevented from colliding with organisms, and the driving safety is improved.

The invention provides a drug-loaded nanoparticle Corr (at) PDA-PEG (at) CD11b and a preparation method and application thereof.The preparation method comprises the following steps that S1, a cordycepin solution and a PDA aqueous solution are mixed, so that cordycepin and PDA form a compound Corr (at) PDA through the pi-pi stacking effect; s2, carrying out PEG (Polyethylene Glycol) modification on the obtained compound Cor(at) PDA to prepare a compound Cor(at) PDA (at) PEG; and S3, dispersing the obtained Corr (at) PDA (at) PEG in a buffer solution, adding an anti-CD11b antibody, reacting for 24 hours, centrifuging, washing, collecting precipitate, and drying to obtain Corr (at) PDA-PEG (at) CD11b. The prepared drug-loaded nanoparticles Corr (at) PDA-PEG (at) CD11b provide a new thought and a new direction for treatment of sepsis-related lung injury, controlled release of cordycepin is realized through the characteristics of the PDA nanoparticles, the problem that cordycepin enters a body and is quickly oxidized and inactivated is avoided, the bioavailability of the cordycepin is improved, and the drug-loaded nanoparticles are suitable for clinical application. By means of immune cell surface specific antibodies and physiological characteristics, rapid chemotaxis recruitment is carried out at the early stage of acute inflammation, rapid and accurate drug targeting is achieved, and sepsis lung injury is relieved.

A demoulding and material taking method and demoulding and material taking device after polymer material synthesis, wherein the demoulding and material taking device is used to drill into a solid polymer synthetic material cooled to room temperature, the drill bit of the demoulding and material taking device is firmly connected to the polymer synthetic material, and the polymer synthetic material is slowly lifted from the bottom of a reaction container by the cooperation of the threaded structure of a screw until it is completely taken out. This method does not require destruction of the reaction container, nor does it require slow dissolution of the polymer synthetic material by adding additional organic solvents, thereby ensuring the safety and efficiency of experimental operations as well as the purity and biosafety of the polymer synthetic material.

The present invention relates to the field of medical facility technology, specifically a biological sampling safety cabinet and an assembly method thereof, comprising a safety cabinet body, a work surface being arranged in the middle of the safety cabinet body, an air supply system being arranged below the work surface, the air supply system comprising an air pump and an air suction nozzle connected to the air pump, an exhaust system being connected to the output end of the air pump, the exhaust system comprising a work surface exhaust part and an air curtain exhaust part, and the work surface exhaust part corresponds to the work surface. The present invention absorbs the air above the exhaust surface and the work surface through the air supply system, forms an air curtain inside the clean air curtain, and the clean air curtain technology ensures the biological safety of the environment when the sampled object takes off the mask. Under the action of the exhaust system and the exhaust nozzle on the other side of the isolation baffle, the clean positive pressure air supply technology is adopted to ensure the biological safety environment of the sampler, and the unique control system technology constitutes a biological sampling safety device, which greatly improves the biological safety of the environment.

The utility model relates to a biosafety type floor drain capable of carrying out pressure test, which structurally comprises a floor drain body, a cover plate and a filter cartridge, the floor drain body comprises a drainage water collecting port and a drainage cylinder body which are connected with each other, an internal thread screw thread is arranged on the inner wall of the top of the joint of the drainage cylinder body and the drainage water collecting port, and the cover plate is detachably arranged on the top of the drainage water collecting port. The cover plate is a stainless steel movable screen frame cover plate, the filter cartridge is inserted into the top of the drainage barrel, the top end of the filter cartridge is clamped at the bottom end of the drainage water collection port in a limiting manner, and the drainage barrel is externally connected with a pressing device or a backwashing device through an internal thread screw thread. The utility model has the advantages that the internal thread is arranged at the bottom of the water collecting hopper of the floor drain, so that the water collecting hopper can be connected with a pressing device or a backwashing device, and the pressure test can be carried out on a drainage pipeline or the backwashing can be carried out on a water trap of the floor drain to clean sediments in the water trap. The welding quality of the drainage pipeline and the leakproofness of a pipeline system can be effectively detected, and the biological safety of a laboratory is ensured; and sediments in the trap of the floor drain can be conveniently cleaned.