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Artificial saliva

A technology of artificial saliva and content, applied in the field of artificial saliva, can solve the problems of short action time, poor taste, poor antibacterial effect, etc., and achieve the effects of preventing infection, high absorption rate, and fresh taste

Inactive Publication Date: 2019-04-19
四川金凯医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing artificial saliva has problems such as short action time, poor taste, and poor antibacterial effect.

Method used

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Effect test

preparation example Construction

[0032] The preparation method of artificial saliva is specifically as follows:

[0033] (1) Weigh essence and humectant, fully stir to obtain solution 1; (2) Weigh sodium chloride, potassium chloride, calcium chloride, magnesium chloride, sweetener, thickener, antioxidant and dissolve in water, 800rpm, 15min, stirring to completely dissolve, to obtain solution 2; (3) adding solution 1 to solution 2, 800rpm, 10min, to obtain solution 3; (4) adding a pH regulator to solution 3, adjusting the pH to 6.0 Can.

Embodiment 1

[0036] An artificial saliva, which is mainly composed of deionized water, and at least a combination of sodium chloride, potassium chloride, calcium chloride, magnesium chloride and bacteriostatic agents are added; the content of sodium chloride is 0.02%; potassium chloride The content of calcium chloride is 0.03%; the content of calcium chloride is 0.02%; the content of magnesium chloride is 0.02%; the antibacterial agent is water-soluble sodium rice zinc, the content is 0.05%; agent, antioxidant and PH regulator; sweetener includes 0.5% xylitol and 1% aspartame; flavor is 0.02% mint flavor; humectant is 1% glycerin; thickener is 0.5% xanthan gum; The oxidant is 0.001% tea polyphenol; the pH regulator is 0.1% citric acid.

Embodiment 2

[0038] An artificial saliva, which uses deionized water as the main component, and at least a combination of sodium chloride, potassium chloride, calcium chloride, magnesium chloride and bacteriostat is added; the content of sodium chloride is 0.1%; potassium chloride The content of calcium chloride is 0.1%; the content of calcium chloride is 0.5%; the content of magnesium chloride is 0.2%; 1% xylitol and 6% acesulfame potassium as sweetener; 0.1% grapefruit flavor as flavor; 2% sorbitol as humectant; 1% sodium alginate as thickener ; Antioxidant is 0.01% tea polyphenol; PH regulator is 0.2% citric acid.

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Abstract

The invention discloses artificial saliva. According to the artificial saliva, deionized water is taken as the primary component, and at least the combination of sodium chloride, potassium chloride, calcium chloride, magnesium chloride and a bacteriostat is added. The artificial saliva has the advantages that the taste is fresh and comfort, no alcohol is added, there exists no irritation, the postoperative symptom of dried mouth of a patient with a tumor can be rapidly relieved, an oral cavity is moisturized, the artificial saliva remains in the oral cavity for a longer period of time, an anti-oxidant is added to prevent or slow down oxidation, the breeding of oral cavity pathogenic bacteria can be inhibited by adding bacteriostatic components, the oral cavity is cleaned to prevent infection, and the artificial saliva has better stability.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to artificial saliva. Background technique [0002] There are usually two reasons for xerostomia: one is physiological xerostomia, which refers to dry mouth caused by changes in salivary gland structure or gland function decline with age, which is more common in normal middle-aged and elderly people; the other is pathological xerostomia. Dryness refers to direct or indirect damage to the glands caused by certain diseases, such as radiotherapy and chemotherapy for head and neck cancer, salivary gland inflammation, oral diseases, etc. According to statistics, the prevalence of xerostomia is about 5.5%-46%, and it is positively correlated with age, and the incidence of xerostomia among the elderly over 60 years old reaches 40%. In view of the above research, it is very valuable to study artificial saliva that can relieve dry mouth and effectively inhibit the growth...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K33/30A61K33/34A61P1/02A61P31/02A61K33/06
CPCA61K33/06A61K33/14A61K33/30A61K33/34A61P1/02A61P31/02A61K2300/00
Inventor 张杰严一红文鹏程
Owner 四川金凯医疗器械有限公司
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