Unlock instant, AI-driven research and patent intelligence for your innovation.

A kind of traditional Chinese medicine composition for improving local circulation disorder, preparation method and application thereof

A circulatory disorder and composition technology, which is applied in the preparation of medicines for the treatment of local circulatory disorders, and the application field of traditional Chinese medicine compositions in pharmacy, can solve the problems of poor local targeting of drug treatment and unfavorable timely treatment of diseases.

Active Publication Date: 2021-05-14
JIANGSU KANION PHARMA CO LTD +1
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the above-mentioned treatment methods are systemic drugs, with a wide range of indications, and the local pertinence of drug therapy is not strong. The patient's drug selection has a certain degree of blindness, and repeated attempts to use drugs are not conducive to the timely treatment of diseases.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of traditional Chinese medicine composition for improving local circulation disorder, preparation method and application thereof
  • A kind of traditional Chinese medicine composition for improving local circulation disorder, preparation method and application thereof
  • A kind of traditional Chinese medicine composition for improving local circulation disorder, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1 A kind of preparation of Chinese medicine composition plaster

[0021] Prescription: 267g raw Arachnium, 200g raw Aconitum, 167g clove, 167g cinnamon, 300g Angelica dahurica, 125g Asarum, 200g Chuanxiong, 125g Xu Changqing, 83g frankincense (made) , 83g myrrh (made) , 63g camphor, 63g borneol.

[0022] The preparation method of this Chinese medicine composition plaster is as follows:

[0023] Take the above-mentioned twelve raw materials, except camphor and borneol, take the ten ingredients such as Tiannanxing, dry at low temperature, pulverize into fine powder, sieve, mix evenly, and set aside. Take another 267g of rosin, 1330g of paraffin, 800g of vaseline, 233g of liquid paraffin, heat to about 100°C, melt, and when the temperature drops to 60°C, add 160g of methyl salicylate, camphor, borneol and the above-mentioned medicinal powder and mix well to prepare Make a coating, paste, cut into sections, cover the lining, slice, and make 1000 pieces, that is,...

Embodiment 2

[0024] Embodiment 2 Chinese medicine composition of the present invention is to the impact of microcirculation disorder rat

[0025] 1 Materials and methods

[0026] 1.1 Experimental animals

[0027] Healthy male SD rats, 50 males, weighing 200g±5g, were purchased from Qinglongshan Animal Breeding Farm, Jiangning District, Nanjing, certificate number: SCXK (Su) 2017-0001.

[0028] 1.2 Experimental drugs and reagents

[0029] The plaster prepared by the above-mentioned embodiment 1;

[0030] Polymer dextran: Dextran500 Sweden

[0031] 1.3 Experimental equipment

[0032] Blood Viscosity Dynamic Analyzer

[0033] 1.4 Experimental method

[0034] 50 SD rats were randomly divided into 5 groups, 10 in each group, respectively normal control group, model control group, plaster high dose group (high dose group), plaster medium dose group (middle dose group), plaster Low-dose group (low-dose group). The model group, high-dose group, and low-dose group were injected with 10% pol...

Embodiment 3

[0049] Embodiment 3 The influence of Chinese medicine composition of the present invention on arterial vasculitis obliterans

[0050] 1 Materials and methods

[0051] 1.1 General information

[0052] Nanjing Drum Tower Hospital recruited 100 patients with arterial vasculitis obliterans, and all patients participated in this study voluntarily. They will be randomly divided into control group and treatment group, with 50 people in each group. There is no statistically significant difference in general data such as gender, age, course of disease, and onset of patients between the two groups, and they are comparable. Inclusion criteria: refer to "Peripheral Vascular Diseases of Integrated Traditional Chinese and Western Medicine".

[0053] Patients diagnosed with arteriosclerotic vasculitis I and II stages; exclusion criteria: patients with severe limb infection or tissue necrosis; patients with insufficiency of important organs such as heart, liver, and kidney.

[0054] 1.2 Tr...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention proposes a traditional Chinese medicine composition for improving local circulatory disorders, characterized in that, in terms of weight ratio, the traditional Chinese medicine composition comprises: 70-110 parts of Radix Sinensis, 50-90 parts of Raw Aconitum, 40-80 parts of Clove Cinnamon 40‑80 parts, Angelica dahurica 80‑120 parts, Asarum 20‑70 parts, Chuanxiong 50‑90 parts, Xu Changqing 20‑70 parts, frankincense 10‑40 parts, myrrh 10‑40 parts, camphor 5 ‑40 parts, borneol 5‑40 parts. Pharmacodynamic research shows that the traditional Chinese medicine composition involved in the present invention has definite curative effect, and it has the effect of treating local circulation disorder.

Description

technical field [0001] The present invention relates to medicines, in particular to the application of a traditional Chinese medicine composition in pharmacy, in particular to raw aracna, raw chuanwu, clove, cinnamon, angelica dahurica, asarum, chuanxiong, Xu Changqing, frankincense (made), myrrh (made) , Camphor, the application of borneol compositions in the preparation of drugs for the treatment of local circulation disorders. Background technique [0002] Local circulation disorder, including local blood circulation disorder and local body fluid circulation disorder. If local blood circulation disorder occurs, there will be abnormalities in local circulating blood volume, such as congestion and ischemia. It can also lead to abnormalities in blood properties and vascular contents, such as congestion and thrombosis, manifested as venous congestion, thrombosis, embolism, and infarction, which are common symptoms of local circulation disorders. Changes in the permeability ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8884A61P9/10A61P9/14A61K31/045A61K31/125A61K31/5575A61K31/616
CPCA61K31/045A61K31/125A61K31/5575A61K31/616A61K36/232A61K36/236A61K36/268A61K36/27A61K36/324A61K36/328A61K36/54A61K36/61A61K36/714A61K36/8884A61P9/10A61P9/14A61K2300/00
Inventor 肖伟李璐杨一帆杨彪曹亮
Owner JIANGSU KANION PHARMA CO LTD