Plant medicine granule serving as feed additive for preventing and treating poultry and livestock diseases and preparation thereof

Abstract

The invention relates to a plant medicine granule serving as a feed additive for preventing and treating poultry and livestock diseases and preparation thereof. A plant medicine composition of the feed additive is made from pine needle, purslane, bupleurum root, astragalus root, phellodendron bark, pulsatilla root, honeysuckle flower, fructus forsythiae, cyrtomium rhizome, hawthorn, folium cortex eucommiae and licorice. The preparation comprises the following steps: adding water to the plant medicine composition, decocting, filtering out, keeping standing, leaching supernatant, condensing, adding a clarificant while stirring, keeping standing for 12h until no precipitate is separated out, leaching supernatant, recondensing, drying and adding pharmaceutic adjuvant to obtain the granule. The plant medicine granule has the advantages of no toxic and side effect, no residue, being safe, definite curative effect, simple preparation method, low cost, being environment-friendly and good application prospect in veterinary drugs.

Description

technical field

[0001] The invention belongs to the field of animal feed additive herbal medicine preparation and its preparation, in particular to a herbal medicine granule used as a feed additive for preventing and treating poultry and animal diseases and its preparation. Background technique

[0002] With the rapid development of the feed industry, a large number of artificially synthesized feed additives such as antibiotics, growth-stimulating hormones, insect repellents, hormones, flavoring agents, improvers, and preservatives are commonly added to feed. The application of these additives has played a huge role in promoting the development of animal husbandry. Western medicine and veterinary medicine have been popular in farms for their high curative effect and quick effect; however, they have also brought negative effects. Synthetic drugs, especially various antibiotics, if used for a long time, will cause many toxic and side effects to animals, and even kill the benef...

Examples

Embodiment 1

[0066] The water extract of the raw material was obtained in the following proportions:

[0067] Take pine needles 15g, purslane 15g, Bupleurum 10g, astragalus 12g

[0068] Phellodendron 6g Pulsatilla 9g Honeysuckle 9g Forsythia 9g

[0069] Guanzhong 9g Hawthorn 9g Eucommia Leaf 10g Licorice 6g

[0070] Wait for the twelve herbal medicine compositions, add 10 times the amount of water, decoct for 2 hours, and filter out the medicinal juice. Add 8 times the amount of water, decoct for 1 hour, filter out the concoction, combine the second decoction, let stand, filter the supernatant, concentrate to a specific gravity of 1.05, add clarifier 0.5% chitosan (1% acetic acid solution ), added to the water extraction concentrate, stirred while adding, and stood still for 12 hours after no precipitation, filtered the supernatant, concentrated to 1.38, dried in vacuum, added 10% dextrin in parts by weight, and made granules. 20-40 mesh sieve for granulation to make 50g granules.

Embodiment 2

[0072] The water extract of the raw material was obtained in the following proportions:

[0073] Take pine needles 30kg, purslane 30kg, bupleurum 20kg, astragalus 20kg

[0074] Cork 12kg Pulsatilla 18kg Honeysuckle 18kg Forsythia 18kg

[0075] Guanzhong 18kg Hawthorn 18kg Eucommia Leaf 20kg Licorice 12kg

[0076] Wait for the twelve herbal medicine compositions, add 10 times the amount of water, decoct for 2 hours, and filter out the medicinal juice. Add 8 times the amount of water, decoct for 1 hour, filter out the concoction, combine the second decoction, let stand, filter the supernatant, concentrate to a specific gravity of 1.05, add clarifier 0.2% chitosan (1% acetic acid solution ), added to the water extraction concentrate, stirred while adding, and stood still for 12 hours after no precipitation, filtered the supernatant, concentrated to 1.38, spray-dried, added 10% dextrin in parts by weight, and made granules. Sieve with 20-40 mesh to make 100kg granules.

Embodiment 3

[0078] The quality index of the granule embodiment one of this composition and example two:

[0079] 【Properties】This product is a granule; the content is a brownish-yellow to brown powder; the gas is slightly fragrant and the taste is slightly bitter.

[0080] 【identification】

[0081] 1. Take 5g of this product, grind it finely, add 50ml of methanol, ultrasonicate for 30 minutes, let it cool, filter, evaporate the filtrate to dryness, add 20ml of water to the residue to dissolve, transfer to a separatory funnel, shake and extract 3 times with ether, 20ml each time, discard the ether solution, shake the aqueous solution with water-saturated n-butanol for 3 times, 20ml each time, combine the n-butanol extracts, wash 3 times with ammonia test solution, 20ml each time, and then use normal butanol Wash with 20ml of butanol-saturated water, evaporate the n-butanol solution to dryness, add 1ml of methanol to dissolve the residue, and use it as the test solution. Another astragalo...

technical field

[0001] The invention belongs to the field of animal feed additive herbal medicine preparation and its preparation, in particular to a herbal medicine granule used as a feed additive for preventing and treating poultry and animal diseases and its preparation. Background technique

[0002] With the rapid development of the feed industry, a large number of artificially synthesized feed additives such as antibiotics, growth-stimulating hormones, insect repellents, hormones, flavoring agents, improvers, and preservatives are commonly added to feed. The application of these additives has played a huge role in promoting the development of animal husbandry. Western medicine and veterinary medicine have been popular in farms for their high curative effect and quick effect; however, they have also brought negative effects. Synthetic drugs, especially various antibiotics, if used for a long time, will cause many toxic and side effects to animals, and even kill the benef...

Examples

Embodiment 1

[0066] The water extract of the raw material was obtained in the following proportions:

[0067] Take pine needles 15g, purslane 15g, Bupleurum 10g, astragalus 12g

[0068] Phellodendron 6g Pulsatilla 9g Honeysuckle 9g Forsythia 9g

[0069] Guanzhong 9g Hawthorn 9g Eucommia Leaf 10g Licorice 6g

[0070] Wait for the twelve herbal medicine compositions, add 10 times the amount of water, decoct for 2 hours, and filter out the medicinal juice. Add 8 times the amount of water, decoct for 1 hour, filter out the concoction, combine the second decoction, let stand, filter the supernatant, concentrate to a specific gravity of 1.05, add clarifier 0.5% chitosan (1% acetic acid solution ), added to the water extraction concentrate, stirred while adding, and stood still for 12 hours after no precipitation, filtered the supernatant, concentrated to 1.38, dried in vacuum, added 10% dextrin in parts by weight, and made granules. 20-40 mesh sieve for granulation to make 50g granules.

Embodiment 2

[0072] The water extract of the raw material was obtained in the following proportions:

[0073] Take pine needles 30kg, purslane 30kg, bupleurum 20kg, astragalus 20kg

[0074] Cork 12kg Pulsatilla 18kg Honeysuckle 18kg Forsythia 18kg

[0075] Guanzhong 18kg Hawthorn 18kg Eucommia Leaf 20kg Licorice 12kg

[0076] Wait for the twelve herbal medicine compositions, add 10 times the amount of water, decoct for 2 hours, and filter out the medicinal juice. Add 8 times the amount of water, decoct for 1 hour, filter out the concoction, combine the second decoction, let stand, filter the supernatant, concentrate to a specific gravity of 1.05, add clarifier 0.2% chitosan (1% acetic acid solution ), added to the water extraction concentrate, stirred while adding, and stood still for 12 hours after no precipitation, filtered the supernatant, concentrated to 1.38, spray-dried, added 10% dextrin in parts by weight, and made granules. Sieve with 20-40 mesh to make 100kg granules.

Embodiment 3

[0078] The quality index of the granule embodiment one of this composition and example two:

[0079] 【Properties】This product is a granule; the content is a brownish-yellow to brown powder; the gas is slightly fragrant and the taste is slightly bitter.

[0080] 【identification】

[0081] 1. Take 5g of this product, grind it finely, add 50ml of methanol, ultrasonicate for 30 minutes, let it cool, filter, evaporate the filtrate to dryness, add 20ml of water to the residue to dissolve, transfer to a separatory funnel, shake and extract 3 times with ether, 20ml each time, discard the ether solution, shake the aqueous solution with water-saturated n-butanol for 3 times, 20ml each time, combine the n-butanol extracts, wash 3 times with ammonia test solution, 20ml each time, and then use normal butanol Wash with 20ml of butanol-saturated water, evaporate the n-butanol solution to dryness, add 1ml of methanol to dissolve the residue, and use it as the test solution. Another astragalo...

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