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A kind of Ganmao granule for clearing away heat and detoxifying exterior surface and preparation method thereof

A granule and formula technology, which is applied in the field of preparation of Ganmao granules for clearing away heat and dispelling skin, and achieves the effects of good solubility, good stability and remarkable curative effect.

Active Publication Date: 2021-04-27
ZHONGSHAN NIKEMEI PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are no reports or patents regarding the compounding of Houttuynia cordata, Shui Yang Mei root, mint leaves, ghost needle grass and Diana chinensis to prepare Ganmao granules in the present invention.

Method used

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  • A kind of Ganmao granule for clearing away heat and detoxifying exterior surface and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The composition and number of servings of the formula in this example are: 15 parts of Houttuynia cordata, 20 parts of salicymus root, 30 parts of mint leaves, 30 parts of ghost needle grass, 15 parts of tea powder (black tea), 10 parts of Dianzhonglou, cyclodextrin 5 parts, 3 parts of magnesium stearate.

[0038] The preparation method of Ganmao granules for clearing away heat and relieving exterior syndrome described in this embodiment comprises the following steps:

[0039] (1) Microwave drying: firstly vacuum-dry Houttuynia cordata, mint leaves and ghost needle grass at microwave frequency 2450MHZ, temperature 40℃, decompression to -0.07MPa until the moisture content is <5%;

[0040] (2) Pulverization: the Houttuynia cordata, mint leaves and ghost needle grass obtained in step 1) were pulverized with a plant pulverizer to 120 meshes and then used;

[0041] (3) Two-stage pulverization: Pulverize the water bayberry root through a 20-mesh sieve with a hammer mill, and...

Embodiment 2

[0045] The formula composition and number of servings in this example are: 20 parts of Houttuynia cordata, 40 parts of salicylic bayberry root, 60 parts of mint leaves, 50 parts of ghost needle grass, 30 parts of tea powder (black tea, black tea, mass ratio 2:1), Dianzhonglou 20 parts, cyclodextrin 15 parts, magnesium stearate 6 parts.

[0046]The preparation method of Ganmao granules for clearing away heat and relieving exterior syndrome described in this embodiment comprises the following steps:

[0047] (1) Microwave drying: firstly vacuum-dry Houttuynia cordata, mint leaves and ghost needle grass at microwave frequency 2450MHZ, temperature 50℃, decompression to -0.09MPa until the moisture content is <5%;

[0048] (2) Grinding: Grind Houttuynia cordata, mint leaves and ghost needle grass obtained in step 1) respectively with a plant grinder to 160 meshes before use;

[0049] (3) Two-stage pulverization: Pulverize the water bayberry root through a 30-mesh sieve with a hamme...

Embodiment 3

[0053] The composition and number of servings of the formula in this example are: 18 parts of Houttuynia cordata, 30 parts of salicylic bayberry root, 45 parts of mint leaves, 40 parts of ghost needle grass, 20 parts of tea powder (Puer tea), 15 parts of Dianzhonglou, cyclopaste 10 parts of essence, 5 parts of magnesium stearate.

[0054] The preparation method of Ganmao granules for clearing away heat and relieving exterior syndrome described in this embodiment comprises the following steps:

[0055] (1) Microwave drying: firstly vacuum-dry Houttuynia cordata, mint leaves and ghost needle grass at microwave frequency 2450MHZ, temperature 45℃, decompression to -0.08MPa until the moisture content is <5%;

[0056] (2) Pulverization: the Houttuynia cordata, mint leaves and ghost needle grass obtained in step 1) were pulverized with a plant pulverizer to 140 meshes and then used;

[0057] (3) Two-stage pulverization: Pulverize the water bayberry root through a 20-mesh sieve with ...

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Abstract

The invention discloses a Ganmao granule for clearing away heat and relieving the exterior and a preparation method thereof. The composition and the number of parts of the formula are: 15-20 parts of Houttuynia cordata, 20-40 parts of salicymus root, 30-60 parts of mint leaves, ghost needles 30 to 50 parts of grass, 15 to 30 parts of tea powder, 10 to 20 parts of Dianzhonglou, 5 to 15 parts of cyclodextrin, and 3 to 6 parts of magnesium stearate. The invention also discloses a preparation method of Ganmao granules for clearing away heat and relieving the exterior, which mainly includes the steps of microwave drying, crushing, dry granulation and the like. The Ganmao granules of the invention do not add sucrose, use less auxiliary materials, have good stability of the granules, are easily dispersed in water, have high content of active ingredients, and have remarkable curative effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating common cold, in particular to a preparation method of Ganmao granules for clearing away heat and relieving exterior syndrome. Background technique [0002] According to the cause of disease, the traditional Chinese medicine divides cold into three types: wind-cold type, wind-heat type and summer-heat type. The wind-cold type is afraid of cold, low-grade fever, muscle pain, and runny nose; the wind-heat type has severe fever, thick yellow sputum, and sore throat; the summer-heat type is afraid of cold, fever, abdominal pain, and diarrhea. Among them, wind-heat cold is caused by the appearance of wind-heat evil criminals and loss of lung energy. Wind-heat cold is more common in summer and autumn, caused by exogenous wind-heat. [0003] At present, there are not many Ganmao granules for clearing away heat and expelling the surface, and among the existing Ganmao granules, so...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61P11/00A61K9/16A61K47/40
CPCA61K9/1652A61K36/28A61K36/534A61K36/73A61K36/78A61K36/82A61K36/896A61K2236/15A61K2236/17A61K2236/333A61K2236/39A61K2236/55A61P11/00A61K2300/00
Inventor 陈嘉锐林泳仪胡伟
Owner ZHONGSHAN NIKEMEI PHARMA
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