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Pharmaceutical composition against benign prostatic hyperplasia

A technology of benign prostatic hyperplasia and composition, applied in the field of drugs for the treatment of benign prostatic hyperplasia, can solve problems such as uncertain curative effect and unexplained mechanism

Active Publication Date: 2019-05-03
闻喜复康心脑专科医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many kinds of drugs extracted from natural products. Although they have certain curative effects on BPH, their curative effects are not certain, and the mechanism has not yet been elucidated.

Method used

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  • Pharmaceutical composition against benign prostatic hyperplasia
  • Pharmaceutical composition against benign prostatic hyperplasia
  • Pharmaceutical composition against benign prostatic hyperplasia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030]Weigh 1080g of sheep red mutton, 540g of kudzu root, 432g of hawthorn, and 432g of medlar, and mix them evenly to obtain a Chinese medicine mixture. Filter, combine the filtrates, concentrate to a relative density of 1.30-1.35 (50°C), dry under reduced pressure (50°C), and pulverize into fine powder. Take another 36g of American ginseng, crush it into fine powder, mix it with the above fine powder, add 280g of soluble starch, mix well, wet granulate, and dry to make 1000g of granule.

Embodiment 2

[0032] Weigh 540g of sheep red mutton, 270g of kudzu root, 216g of hawthorn, and 216g of medlar and mix them evenly to obtain a Chinese medicine mixture. Filter, combine the filtrates, concentrate to a relative density of 1.30-1.35 (50°C), dry under reduced pressure (50°C), and pulverize into fine powder. Take another 18g of American ginseng, crush it into fine powder, mix it with the above fine powder, add 140g of maltodextrin, mix well, wet granulate, put into capsules, and obtain 1000 capsules.

Embodiment 3

[0034] Weigh 360g of sheep red mutton, 180g of kudzu root, 144g of hawthorn, and 144g of medlar and mix them evenly to obtain a Chinese medicine mixture. Filtrate, combine the filtrates, concentrate into a thick paste with a relative density of 1.40-1.45 (60°C), add 12g of American ginseng crushed into fine powder, mix well, add 750g of heated and melted polyethylene glycol 6000, mix well, drop into Drop pills are made in cooled liquid paraffin.

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Abstract

The invention discloses a pharmaceutical composition against benign prostatic hyperplasia. The composition is a preparation prepared from the following raw material medicines in parts by weight: 20-60parts of all-grass of thellung pimpinella, 10-40 parts of kudzuvine roots, 5-20 parts of hawthorn fruits, 5-20 parts of Chinese wolfberry fruits, and 1-4 parts of American ginseng. The pharmaceuticalcomposition of the present invention is useful for treating benign prostatic hyperplasia with definite effect. Experiments on a rat prostatic hyperplasia model find that the pharmaceutical composition of the invention can improve the body hormone endocrine disorder of the animal model, enhance the antioxidant capacity of the animal model, and have a good therapeutic effect on benign prostatic hyperplasia induced by testosterone propionate.

Description

technical field [0001] The invention relates to a medicine for treating benign prostatic hyperplasia, in particular to a pharmaceutical composition for treating benign prostatic hyperplasia prepared from Chinese herbal medicines as raw materials. Background technique [0002] Benign prostatic hyperplasia (BPH) is the most common cause of dysuria in middle-aged and elderly men. The initial symptoms of BPH are mainly frequent urination and poor urination, which gradually worsen in the later stage to dysuria and increased nocturia. Severe obstructive symptoms can lead to acute urinary retention, bladder stones, and even urine reflux to the kidneys causing hydronephrosis and renal function damage and other serious complications. BPH is an age-related disease, and generally the older you are, the higher the risk of getting the disease. Epidemiological surveys show that the incidence of BPH in men over 60 years old exceeds 50%, and the incidence of BPH in men over 80 years old e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P13/08
Inventor 裴妙荣李慧峰曾桐春
Owner 闻喜复康心脑专科医院
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