The invention discloses a novel medicament for penis built-in pills, a preparation method and a medicament placing device thereof. The novel medicament comprises a tamsulosin urethral water flooding pill, a sarcolysin penis built-in dropping pill and a testosterone propionate urethral lipid pill. When the medicament placing device is used, firstly, the penis is conventionally disinfected, the outer side of a medicament injection hose of the medicament placing device filled with pills is coated with glycerinum for lubrication, the medicament injection hose is inserted into the penis urethra, amedicament pushing rod is pushed forwards, and a corresponding number of pills are injected according to the required injection dosage. The administration mode and the administration path are changed,and rear-end medication of liver and kidney metabolism is adopted. In the treatment and health care process of men, a target organ can be used for direct administration, absorption and effect taking,the medicament composition is small, the medicament concentration in local blood is high, the medicament effect is strong, the medicament can take effect while being absorbed during urethra administration, the non-absorbed medicament is excreted in a harmless manner, and the medicament is a safe and efficient novel administration way, a novel medication mode and a novel medicament, and has a relatively high market prospect and a relatively strong medicament research and development prospect.