Preparation method of medicine for treating acnes

A drug and acne technology, applied in the field of medicine, can solve the problems of patients with pigmented spots or scars, poor treatment effect, etc., and achieve the effect of excellent effect, stable output, and large breeding volume

Inactive Publication Date: 2019-05-31
都江堰同兴金色池塘大鲵养殖有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Acne is a skin disease. Once it occurs, whether it is mild or severe, its damage may leave pigmented spots or scars on the patient, and bring negative effects on the patient's psychology and social interaction. However, the current drug treatment is not effective. Good, difficult to meet people's needs

Method used

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  • Preparation method of medicine for treating acnes
  • Preparation method of medicine for treating acnes
  • Preparation method of medicine for treating acnes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] A preparation method of a medicament for treating acne, comprising the following steps: taking 5 g of giant salamander skin extract and 15 g of vaseline, mixing, and grinding to obtain the medicament for treating acne.

[0014] Among them, the preparation process of giant salamander skin extract includes the following steps: take live giant salamander skin and directly grind it into a homogenate, add 20 times the volume of 3% acetic acid, extract for 30 minutes, stir slowly during the period, and adjust the pH to 6.5 with sodium hydroxide , collect the supernatant, re-extract the residue once according to the above steps, combine the supernatants, and then dry them under reduced pressure at 60° C. to obtain the giant salamander skin extract.

Embodiment 2

[0016] A preparation method of a medicament for treating acne, comprising the following steps: taking 10 g of giant salamander skin extract and 10 g of vaseline, mixing and grinding, and obtaining the medicament for treating acne.

[0017] Among them, the preparation process of giant salamander skin extract includes the following steps: take giant salamander live skin, dry it at 25°C and crush it into 50-mesh powder, add 35 times the volume of 3% acetic acid, extract for 120 minutes, stir slowly during the period, and oxidize it with hydrogen Adjust the pH to 7.5 with sodium, collect the supernatant, re-extract the residue once according to the above steps, combine the supernatant, and then dry under reduced pressure at 60°C to obtain the extract of giant salamander skin.

Embodiment 3

[0019] Get each 1g of the prepared medicine in example 1 and example 2 respectively, and carry out bacteriostasis test.

[0020] Escherichia coli (G+), Pseudomonas aeruginosa (G-), and Staphylococcus aureus (G+) were used as indicator strains, and the antibacterial activity was tested by double-layer plate method and punching method. The slant of the strain was cultured overnight, and the physiological saline was adjusted to 0.5 McFarland turbidity (1×10 8 CFU / mL), adopt the double-layer plate method, that is, the lower layer is pure culture medium, and the upper layer is mixed bacteria culture medium. Punch holes in the upper layer with a diameter of 6mm, add 0.5mL of the sample solution to be tested in each space, incubate upside down at 36°C for 18-24h, measure the size of the inhibition zone, repeat 3 times for each sample, and take the average value, the inhibition zone is greater than 2mm, Significant ++ is recorded, inhibition zone is less than 2 and greater than 0 mm ...

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Abstract

The invention belongs to the field of medicines, and particularly relates to a preparation method of a medicine for treating acnes. The preparation method comprises the following steps that 5-10 partsby weight of a giant salamander skin extract and 10-15 parts by weight of vaseline are uniformly mixed and ground to obtain the medicine for treating acnes. The medicine has an excellent effect on treating acnes. The medicine has a relatively good bacteriostatic effect on staphylococcus aureus and salmonella, has the effects of treating acnes, diminishing inflammation, relieving swelling, removing grease, clearing away heat and eliminating dampness, promoting blood circulation and eliminating acnes, does not have side effects and meets requirements of people.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a preparation method of a medicine for treating acne. Background technique [0002] Acne, commonly known as acne, is a common chronic inflammatory disease of hair follicles and sebaceous glands, which occurs mostly in adolescence. Acne is a skin disease. Once it occurs, whether it is mild or severe, its damage may leave pigmented spots or scars on the patient, and bring negative effects on the patient's psychology and social interaction. However, the current drug treatment is not effective. Good, difficult to meet people's needs. Contents of the invention [0003] In order to solve the above-mentioned technical problems, the present invention provides a preparation method of a medicine for treating acne. The medicine of the present invention has an excellent effect in treating acne. The medicine has good antibacterial effect on Staphylococcus aureus and Salmonella, and is u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/65A61P17/10A61P31/04A61P31/02A61P29/00
CPCY02A50/30
Inventor 朱利专翁玉萍周宜军
Owner 都江堰同兴金色池塘大鲵养殖有限责任公司
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