Kit for detecting common drugs in hair, pretreatment method and detection method

Abstract

The invention discloses a kit for detecting common drugs in hair, a pretreatment method and a detection method. The kit comprises first extracting solution and second extracting solution, wherein thefirst extracting solution is borax buffer solution, and the second extracting solution is mixed solution of chloroform and isopropanol. Compared with a conventional detection method, the detection method provided by the invention employs the kit containing the extracting solution of common drugs in hair for extraction operation in sample pretreatment, is good in effect for the extracting solutionand can provide a good basis for qualitative analysis, and the whole pretreatment process can be completed within about 0.5h, so that the pretreatment time is effectively shortened; moreover, the pretreatment method combining the kit with liquid-liquid extraction is adopted during sample pretreatment, so that the cost can be effectively saved, the universality of an identification mechanism is higher, and the superiority is more obvious.

Description

technical field [0001] The invention relates to the technical field of drug detection, in particular to a kit, a pretreatment method and a detection method for detecting common drugs in hair. Background technique [0002] According to literature reports, among the commonly used pretreatment methods for drug detection in hair, it takes 12-15 hours to use acid hydrolysis, which is time-consuming and cannot meet the needs of rapid screening. Frozen grinding technology is a pretreatment technology developed in recent years. After the hair is crushed, the contact surface with the solvent is increased, and the release of drugs in the hair is increased. However, a large amount of liquid nitrogen is required for freezing, and the cost is high. Therefore, domestic third-party judicial It is difficult for appraisal institutions to popularize frozen grinding equipment for a while. Therefore, in actual forensic work, there is an urgent need for a simple, fast, and cost-effective detect...

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Problems solved by technology

[0002] According to literature reports, among the commonly used pretreatment methods for drug detection in hair, acid hydrolysis takes 12h to 15h, which is time-consuming and cannot meet the needs of rapid screening.

Frozen grinding technology is a pretreatment technology developed in recent years. After the hair is crushed, the contact surface with the solvent is increased, and the release of drugs in the hair is increased. However, a large amount of liquid nitrogen is required for freezing, and the cost is high. Therefore, domestic third-party judicial It is difficult for the appraisal institution to popularize the freezing and grinding equipment for a while

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