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The manufacture method of nasal drop composition

A manufacturing method and technology of nasal drops, which can be applied in the direction of drug combination, drug delivery, and pharmaceutical formulations, and can solve problems such as difficult to show effects

Active Publication Date: 2020-10-30
WELL STONE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Various studies have been carried out on such nasal drop compositions (for example, Patent Documents 1 and 2), but as a general theory, different nasal drop compositions are being sought due to the fact that it is difficult to express effects depending on the subject.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0115]

[0116] Observe the following subjects who have sprayed the nasal drop composition obtained above every day, 6 to 10 times a day, 2 to 5 times with a commercially available nasal cavity cleaning sprayer, and sprayed it in the nasal cavity in the form of mist. symptoms of hay fever in patients.

[0117] Subject: female, 22 years old: 2 years of medical records

[0118] After 3 days, nasal discharge and tears decreased

[0119] After 7 days, the nasal discharge and tears stopped

[0120] Hay fever pain lessened after 15 days

[0121] After 30 days, healed

Embodiment 2

[0123]

[0124] Observe the following subjects who have sprayed the nasal drop composition obtained above every day, 6 to 10 times a day, 2 to 5 times with a commercially available nasal cavity cleaning sprayer, and sprayed it in the nasal cavity in the form of mist. symptoms of hay fever in patients.

[0125] Subject: Male, 52 years old: 15 years of medical records

[0126] After 7 days, the runny nose and itchy eyes are reduced

[0127] After 14 days, the runny nose and itching disappeared

[0128] After 25 days, symptoms improved

[0129] After 30 days, symptoms disappear

Embodiment 3

[0131]

[0132] Observe that the nasal drop composition obtained above has been sprayed 2 to 5 times with a commercially available nasal cavity cleaning sprayer every day, 6 to 10 times a day, and sprayed in the nasal cavity in the form of mist. Symptoms of empyema in the subject.

[0133] Subject: male, 18 years old: medical history 2 months old, with yellow nasal discharge

[0134] After 7 days, the amount and color of nasal fluid decreased

[0135] After 10 days, the runny nose stopped

[0136] After 25 days, the nose was opened and healed

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PUM

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Abstract

The present invention is to provide a method for producing a nasal drop composition suitable for treating or preventing diseases or symptoms in the nasal cavity, and a nasal drop composition obtained by the method. It is a manufacturing method of a nose drop composition and a nasal drop composition obtained by using the manufacturing method, and the manufacturing method of the nasal drop composition is characterized in that it includes the following steps: mixing the excrement of earthworms with water step; and a step of recovering vaporized water generated from the mixture obtained in the aforementioned mixing step to obtain a liquid. In the mixing step, it is preferable to further mix the organic matter with the excrement of the earthworms and the water.

Description

technical field [0001] The present invention relates to a production method of a nasal drop composition suitable for treating or preventing diseases or symptoms in the nasal cavity and a nasal drop composition obtained by the production method. Background technique [0002] Conventionally, nasal drop compositions have been used for the treatment and prevention of hay fever and empyema. Various studies have been conducted on such nasal drop compositions (for example, Patent Documents 1 and 2), but as a general theory, different nasal drop compositions are being sought because it is difficult to express effects depending on the subject. [0003] prior art literature [0004] patent documents [0005] Patent Document 1: Japanese Patent No. 4591810 [0006] Patent Document 2: Japanese Patent No. 4790096 Contents of the invention [0007] Invention to solve problem [0008] Therefore, an object of the present invention is to provide a method for producing a nasal drop com...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/62A61K9/12A61K9/72A61K35/02A61K36/15A61K36/13A61K33/14A61K33/06A61P11/02A61P37/08
CPCA61P11/12A61K35/62A61K36/13A61K9/0043A61P11/02
Inventor 石井阳一冈本猛牧野纱也香
Owner WELL STONE