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Antibacterial gel for gynaecology

A gel, gynecological technology, applied in the direction of antibacterial drugs, topical antibacterial agents, plant/algae/fungus/moss components, etc. Improved microenvironment, low cost of preparation, and small side effects

Inactive Publication Date: 2019-08-30
郑玉峰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when these traditional antibacterial gels are injected into the vagina, they tend to become thinner immediately when they encounter salt and electrolytes in the human body. Low efficacy, poor therapeutic effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A gynecological antibacterial gel, comprising the following components by weight: 0.5 parts of tragacanth gum, 0.6 parts of juniper oil, 0.3 parts of Houttuynia cordata extract, 0.1 part of mugwort extract, 0.2 parts of geranium extract, and Gastrodia elata extract 0.2 parts, 0.1 parts of garlic extract, 2 parts of hydroxypropyl gamma cyclodextrin, 0.5 parts of methyl 6-chloro-6-deoxy-alpha-D-glucopyranoside ionized diethylaminoethyl cellulose, 0.1 part of silver glycyrrhizinate, 1 part of glycerin, 0.1 part of triethanolamine, 60 parts of water.

[0024] The preparation method of the methyl 6-chloro-6-deoxy-alpha-D-glucopyranoside ionized diethylaminoethyl cellulose comprises the following steps: methyl 6-chloro-6-deoxy-alpha- Add 100g of D-glucopyranose (CAS: 4144-87-0) and 300g of diethylaminoethyl cellulose into 1500g of N,N-dimethylformamide, stir and react at 60°C for 6 hours, then spin evaporate The solvent was removed, the product was extracted with water, and ...

Embodiment 2

[0028] A gynecological antibacterial gel, comprising the following components in parts by weight: 0.7 parts of tragacanth gum, 0.7 parts of juniper oil, 0.45 parts of Houttuynia cordata extract, 0.2 parts of mugwort extract, 0.35 parts of geranium extract, Gastrodia elata extract 0.35 parts, 0.25 parts of garlic extract, 2.3 parts of hydroxypropyl gamma cyclodextrin, 0.7 parts of methyl 6-chloro-6-deoxy-alpha-D-glucopyranoside ionized diethylaminoethyl cellulose, 0.15 parts of silver glycyrrhizinate, 1.5 parts of glycerin, 0.15 parts of 6-amino-4-(hydroxymethyl)-4-cyclohexyl-[4H,5H]-1,2,3-triol, 63 parts of water.

[0029] The preparation method of the methyl 6-chloro-6-deoxy-alpha-D-glucopyranoside ionized diethylaminoethyl cellulose comprises the following steps: methyl 6-chloro-6-deoxy-alpha- Add 100g of D-glucopyranose (CAS: 4144-87-0) and 350g of diethylaminoethyl cellulose into 1700g of N,N-dimethylacetamide, stir and react at 65°C for 6.5 hours, then spin evaporate The...

Embodiment 3

[0033] A gynecological antibacterial gel, comprising the following components in parts by weight: 1 part of tragacanth gum, 0.85 part of juniper oil, 0.55 part of Houttuynia cordata extract, 0.3 part of mugwort extract, 0.45 part of geranium extract, Gastrodia elata extract 0.35 parts, 0.3 parts of garlic extract, 2.5 parts of hydroxypropyl gamma cyclodextrin, 1 part of methyl 6-chloro-6-deoxy-alpha-D-glucopyranoside ionized diethylaminoethyl cellulose, 0.2 parts of silver glycyrrhizinate, 2 parts of glycerin, 0.2 parts of diethanolamine, 65 parts of water.

[0034] Further, the pH regulator is preferably at least one of triethanolamine, 6-amino-4-(hydroxymethyl)-4-cyclohexyl-[4H,5H]-1,2,3-triol, .

[0035] Further, the preparation method of methyl 6-chloro-6-deoxy-alpha-D-glucopyranoside ionized diethylaminoethyl cellulose comprises the following steps: methyl 6-chloro-6-deoxy -alpha-D-glucopyranose (CAS: 4144-87-0) 100g, diethylaminoethyl cellulose 400g were added to N-met...

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PUM

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Abstract

The invention discloses antibacterial gel for gynaecology. The antibacterial gel comprises the following components in parts by weight of 0.5-1.5 parts of astragalus gummifer gum, 0.6-1 part of sabinaoil, 0.3-0.7 part of a heartleaf houttuynia herb extract, 0.1-0.4 part of an argy wormwood extract, 0.2-0.6 part of a pelargonium extract, 0.2-0.5 part of a rhizoma gastrodiae extract, 0.1-0.4 part of a garlic extract, 2-3 parts of hydroxypropyl-gamma-cyclodextrin, 0.5-1.5 parts of methyl-6-chlorine-6-deoxidized-alpha-D-glucopyranoside ionized diethyllaminoethyl cellulose, 0.1-0.3 part of silverglycyrrhetate, 1-3 parts of glycerine, 0.1-0.3 part of a PH regulator and 60-70 parts of water. The invention further discloses a preparation method of the antibacterial gel for gynaecology. The preparation method of the antibacterial gel coagulation for gynaecology disclosed by the invention is simple, and the antibacterial gel is low in preparation cost, good in antibacterial properties, good instability and significant in repair effects, can effectively prevent and treat gynecological diseases of vaginitis and the like, can promote regeneration and relieve pain, and is small in side effects and safe to use.

Description

technical field [0001] The invention relates to the technical field of gynecological medical care, in particular to a gynecological antibacterial gel. Background technique [0002] Diseases of the female reproductive system are gynecological diseases, including vulvar diseases, cervicitis, vaginitis, fallopian tube diseases, ovarian diseases, etc. It is a common and frequently-occurring disease in women. The cause of the disease is mainly due to the physiological structure of the female vagina, which determines that it is susceptible to infection by exogenous viruses and bacteria. In addition, due to poor living habits or high work pressure, some patients have poor immunity, resulting in long-term gynecological diseases. , Bring great inconvenience to normal life. These diseases directly affect women's physical and mental health, and even lead to premature aging. [0003] At present, there are many drugs for the treatment of gynecological diseases. Oral drug dosage forms a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61K9/06A61K47/36A61K47/38A61K47/40A61P15/02A61P31/02A61P31/04A61K33/38A61K31/724A61K31/704
CPCA61K9/0034A61K9/06A61K31/704A61K31/724A61K33/38A61K36/185A61K36/282A61K36/78A61K36/8962A61K36/8988A61K47/36A61K47/38A61K47/40A61P15/02A61P31/02A61P31/04A61K2300/00
Inventor 郑玉峰孙晓英刘玉新
Owner 郑玉峰
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