Alkali-resistant vibrio alginolyticus phage and composition thereof and kit, and application thereof

A technology of Vibrio alginolyticus and bacteriophage, which is applied in the direction of bacteriophage, virus/phage, medical raw materials derived from virus/phage, etc. good stability
CN110205305AActive Publication Date: 2019-09-06PHAGELUX (NANJING) BIO-TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
PHAGELUX (NANJING) BIO-TECH CO LTD
Publication Date
2019-09-06

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Abstract

The invention belongs to the technical field of research and development of vibrio alginolyticus phage, and in particular, relates to an alkali-resistant vibrio alginolyticus phage and a composition thereof, and a kit. The vibrio alginolyticus phage is vibrio alginolyticus phage VAP21, and has the preservation number of CCTCC NO:M 2018768. The invention also discloses an application of the vibrioalginolyticus phage, or a vibrio alginolyticus phage composition, or a reagent or kit containing the vibrio alginolyticus phage or the vibrio alginolyticus phage composition in killing and / or preventing vibrio microorganisms. The vibrio alginolyticus phage has wide host range, still has high toxicity to host bacteria at low concentration, good proliferation on non-pathogenic bacteria host and large-scale industrial production, and can provide excellent strain resources for an application of phagotherapy.
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Description

technical field

[0001] The invention belongs to the technical field of research and development of vibrio alginolyticus phage, and in particular relates to an alkali-resistant vibrio alginolyticus phage and its composition, kit and application. Background technique

[0002] Vibrio alginolyticus is a halophilic Gram-negative short bacillus without spores and capsules, belonging to the family Vibrio and the genus Vibrio. the first. It can cause wound infection, food poisoning, otitis media and other diseases to humans. At the same time, it is also an opportunistic pathogen for fish, shrimp, shellfish and other marine aquaculture animals. When the environment deteriorates, the body's immune function decreases, and alginolytic vibriosis is prone to outbreaks.

[0003] Bacteriophage is a type of virus that specifically lyses bacteria. Its main chemical components are composed of protein and nucleic acid. It is widely found in soil, air, water and organisms, and has strong speci...

Claims

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