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Gynecological disease detection preparation and treatment preparation

A technology for gynecological diseases and preparations, which is applied in the field of gynecological diseases, can solve the problems of short decolorization time, long dyeing time, and unsuitability for automatic instruments, etc., and achieves the effect of not being easy to false positive and false negative, not easy to precipitate and deteriorate, and stable dyeing effect

Inactive Publication Date: 2019-10-11
江西业力医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. The dyeing time is longer, which affects the efficiency of clinical testing (currently, the average sample size of domestic clinical vaginal secretion routine inspection is about 200 persons / day);
[0005] 2. It is not suitable for the development of automated instruments, mainly because the decolorization time of the third solution in the traditional Gram staining solution is relatively short (5-10s);
[0007] 4. The second solution made by simply mixing iodine and potassium iodide cannot provide an optimal reaction environment, which hinders the combination of bacteria and crystal violet-iodine complex, resulting in unstable staining effect;
[0008] 5. The simple fourth liquid safflower solution is easy to deteriorate and should not be stored for a long time
However, whether it is pure traditional Chinese medicine or a combination of traditional Chinese medicine and chemical ingredients, the abuse of these bactericidal substances will seriously damage the vaginal self-cleaning system, directly lead to vaginal flora disorder, make gynecological diseases prone to relapse, and the treatment effect is not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A gynecological disease detection preparation is composed of a first liquid, a second liquid, a third liquid and a fourth liquid.

[0024] The first liquid is composed of the following components by weight percentage: crystal violet 0.5%, ammonium oxalate 0.3%, ethanol 5%, polyethylene glycol 2002%, triton 1%, distilled water balance; The second liquid is composed of the following components by weight percentage: 0.8% iodine, 1% potassium iodide, 0.1% hydrochloric acid, and the remainder of distilled water; the third liquid is composed of the following components by weight percentage: 15% acetone, ethanol 60%, glutaraldehyde 25%; the fourth liquid consists of the following components by weight percentage: basic fuchsin 0.3%, phenol 0.1%, ethanol 5%, polyethylene glycol 2002%, koji Pass 0.5%, the balance in distilled water.

[0025] The preparation method of the gynecological disease detection preparation is as follows:

[0026] 1. The first liquid preparation process:...

Embodiment 2

[0056] A gynecological disease detection preparation is composed of a first liquid, a second liquid, a third liquid and a fourth liquid.

[0057] The first liquid is composed of the following components by weight percentage: crystal violet 1.5%, ammonium oxalate 1.5%, ethanol 20%, polyethylene glycol 4005%, Tween 205%, distilled water surplus; control the pH value at Between 5.5-6.0.

[0058]The second liquid is composed of the following components by weight percentage: 2.3% iodine, 4% potassium iodide, 0.5% hydrochloric acid, and the remainder of distilled water; the pH value is controlled between 1.5-2.0.

[0059] The third liquid is composed of the following components by weight percentage: acetone 35%, ethanol 60%, glutaraldehyde 5%;

[0060] The fourth liquid consists of the following components by weight percentage: basic fuchsin 0.8%, phenol 0.6%, ethanol 15%, polyethylene glycol 4008%, Tween 203%, distilled water remainder; pH control The value is between 6.0-6.5.

...

Embodiment 3

[0063] A gynecological disease detection preparation is composed of a first liquid, a second liquid, a third liquid and a fourth liquid.

[0064] The first liquid is composed of the following components by weight percentage: 0.6% crystal violet, 0.6% ammonium oxalate, 8% ethanol, 6002% polyethylene glycol, 801% Tween, and the remainder of distilled water; the pH value is controlled at Between 5.5-6.0.

[0065] The second liquid is composed of the following components by weight percentage: 1.2% iodine, 2% potassium iodide, 0.1% hydrochloric acid, and the remainder of distilled water; the pH value is controlled between 1.5-2.0.

[0066] The third liquid is composed of the following components by weight percentage: 20% acetone, 70% ethanol, 10% glutaraldehyde;

[0067] The fourth liquid consists of the following components by weight percentage: basic fuchsin 0.4%, phenol 0.2%, ethanol 8%, polyethylene glycol 6003%, Tween 801%, distilled water remainder; pH control The value is ...

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PUM

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Abstract

The invention discloses a gynecological disease detection preparation, and belongs to the technical field of gynecological diseases; and the gynecological disease detection preparation is used for detecting the gynecological disease. The gynecological disease detection preparation comprises first liquid, second liquid, third liquid and fourth liquid; the first liquid is composed of the following components including, by mass, 0.5%-1.5% of crystal violet, 0.3%-1.5% of ammonium oxalate, 5%-20% of ethyl alcohol, 2%-5% of polyethylene glycol, 1%-5% of Triton and / or Tween and the balance distilledwater; the second liquid is composed of the following components including, by mass, 0.8%-2.3% of iodine, 1%-4% of potassium iodide, 0.1%-0.5% of hydrochloric acid and the balance distilled water; thethird liquid is composed of the following components including, by mass, 15%-35% of acetone, 40%-70% of ethyl alcohol and 5%-25% of glutaraldehyde; and the fourth liquid is composed of the followingcomponents i including, by mass, 0.3%-0.8% of basic fuchsin, 0.1%-0.6% of phenol, 5%-15% of ethyl alcohol, 2%-8% of polyethylene glycol, 0.5%-3% of Triton and / or Tween and the balance distilled water.The detection preparation provided by the invention is easy to prepare, easy to store and not prone to sediment and going bad, and the storage time can be up to 2 years; the detection preparation provided by the invention can be compatible with manual dying or automatic dying of the instrument, and the manual dying can be completed within the relatively short time.

Description

technical field [0001] The invention belongs to the technical field of gynecological diseases, and in particular relates to a detection preparation and a treatment preparation for gynecological diseases. Background technique [0002] Vaginal secretion detection is the most common detection item in gynecology, and it is the simplest and most commonly used detection method for diagnosing female external genital tract infection. Through the detection of the appearance, cleanliness, epithelial cells, white blood cells, various bacteria, fungi and parasites of female vaginal secretions, a systematic evaluation of the microecology in the vagina is made to understand the health status of women. [0003] According to the "National Clinical Testing Operation Regulations", the standard operation of routine testing of vaginal secretions requires Gram staining. The advantage of Gram staining is that bacteria and fungi are easy to judge, but traditional Gram staining has the following p...

Claims

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Application Information

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IPC IPC(8): G01N1/30G01N15/10A61K35/747A61P15/00
CPCG01N1/30G01N15/10A61K35/747A61P15/00G01N2001/302G01N2015/1006G01N2015/1022G01N2015/1024A61K2300/00
Inventor 熊文芳吕正和陈永洪杜厚明杨平平侯莉赖文成
Owner 江西业力医疗器械有限公司
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