Bacteriostatic contraceptive gel containing total alkaloids of sophora alopecuroides for gynecology department

A technology of sophora bean and gel, which is applied in the field of medical care products, can solve the problems of large side effects and weak antibacterial effect of synthetic chemical components, avoid the side effects of the vagina, increase the viscosity and hardness of the gel, and maintain the antibacterial effect. effective effect

Inactive Publication Date: 2019-10-15
江苏加南美地生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Based on the technical problems existing in the background technology, the present invention proposes a gynecological antibacterial and contraceptive gel containing the total alkaloids of Sophora Sophorae, which has quick effect, good contraceptive effect, good antibacterial effect and continuous effective antibacterial effect, and is effective for vaginal The advantage of no influence on the internal environment, solves the problem of relatively large side effects of traditional synthetic chemical components, and the general weak antibacterial effect of traditional contraceptive gels

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A gynecological antibacterial and contraceptive gel containing the total alkaloids of Sophora sophora, the components are 1% of the total alkaloids of Sophora sophora, 4.5% of lupeol, 4.5% of camellia saponin, 4.5% of pulsatilla saponin, glycol 1.5% acid, 1% agave extract, 1% VC ethyl ether, 1% humectant, 1% xanthan gum, 30% matrix, 1% preservative, and the balance is deionized water.

[0037] The samples of Example 1 were sampled and tested with reference to "GB15979-2002 Hygienic Standards for Disposable Sanitary Products" and "QB / T2738-2012 Evaluation Method for Antibacterial and Antibacterial Effects of Daily Chemical Products" standard test: the number of bacterial colonies was 12, and the vaginal mucosa was irritated Test and skin allergy test are normal pass. The antibacterial rate to Staphylococcus aureus test is 87%, and the bacteriostatic rate to Pseudomonas aeruginosa test is 94%.

[0038] The sperm inactivation effect test was carried out on the sample of E...

Embodiment 2

[0040] A kind of antibacterial and contraceptive gel for gynecology containing the total alkaloids of Sophora sophora, the components are 2% of total alkaloids of Sophora sophora, 5.5% of lupeol, 5.5% of camellia saponin, 5.5% of pulsatilla saponin, glycol 3% acid, 1.5% agave extract, 1.5% VC ethyl ether, 1.5% humectant, 3% xanthan gum, 37.5% matrix, 1.5% preservative, and the balance is deionized water.

[0041]The samples of Example 2 were sampled and tested with reference to the standards of "GB15979-2002 Hygienic Standard for Disposable Sanitary Products" and "QB / T2738-2012 Evaluation Method for Antibacterial and Antibacterial Effects of Daily Chemical Products": the number of bacterial colonies was 10, and the vaginal mucosa was irritated. Test and skin allergy test are normal pass. The antibacterial rate to Staphylococcus aureus test is 95%, and the bacteriostatic rate to Pseudomonas aeruginosa test is 97%.

[0042] The sperm inactivation effect test was carried out on ...

Embodiment 3

[0044] A kind of gynecological antibacterial contraceptive gel containing the total alkaloids of Sophora aphorae, the components are 2.9% of total alkaloids of Sophora sophora, 7% of lupeol, 7% of camellia oleifera saponin, 7% of pulsatilla saponin, glycol Acid 4%, agave extract 2%, VC ethyl ether 2%, humectant 2%, xanthan gum 5%, matrix 45%, preservative 2%, and deionized water as the balance.

[0045] The sample of Example 3 was sampled and tested with reference to the standards of "GB15979-2002 Hygienic Standard for Disposable Sanitary Products" and "QB / T2738-2012 Evaluation Method for Antibacterial and Antibacterial Effects of Daily Chemical Products": the number of bacterial colonies was 9, and the vaginal mucosa was irritated Test and skin allergy test are normal pass. The antibacterial rate to Staphylococcus aureus test is 97%, and the bacteriostatic rate to Pseudomonas aeruginosa test is 99%.

[0046] The sperm inactivation effect test was carried out on the sample of...

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Abstract

The invention relates to the technical field of medical and nursing appliances and particularly discloses bacteriostatic contraceptive gel containing total alkaloids of sophora alopecuroides for the gynecology department. The bacteriostatic contraceptive gel is prepared from the following components: total alkaloids of sophora alopecuroides, a contraceptive effective ingredient, agave Americana extract, VC ethyl ether, a wetting agent, xanthan gum, matrix and deionized water. The contraceptive gel has the effects of contraceptive gel and the effects of bacteriostatic gel, has an effect of efficiently killing sperms of human bodies with the response rate of 100 percent, has a relatively strong inhibition effect and a bacteriostatic rate being 94 percent or more by adding the total alkaloidsof sophora alopecuroides, can avoid the side effect of long-time use of traditional synthesized chemical contraceptive ingredients on the vagina as far as possible while ensuring the contraceptive effect, does not influence the acid environment and normal flora in the vagina by repeated use and is suitable for nursing before and after sexual intercourses and daily nursing for reproductive organsof males and females.

Description

technical field [0001] The invention relates to the technical field of medical care products, in particular to a gynecological antibacterial and contraceptive gel containing the total alkaloid component of Sophora Sophora. Background technique [0002] Most of the gynecological contraceptive gels currently on the market are mainly composed of nonoxynol, octoxynol and other chemical spermicidal surfactants, which have relatively large side effects after use. 60-70% of women will feel vaginal burning and even pain. Individuals will have a small amount of bleeding, which is mostly caused by the stimulation of the vaginal mucosa by these chemical surfactants. Long-term use of these contraceptive gels will not only cause damage to the vaginal mucosa, but also interfere with and destroy the normal physiological environment of the vagina, causing gynecological infections such as the vagina and even the uterus and pelvic cavity. Moreover, these gynecological contraceptive gels gene...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K47/36A61K36/88A61P31/04A61P15/18A61K31/375A61K31/56A61K31/704A61K31/19
CPCA61K9/06A61K9/0034A61K47/36A61K36/489A61K36/88A61K31/375A61K31/56A61K31/704A61K31/19A61P31/04A61P15/18A61K2300/00
Inventor 赵丽娟
Owner 江苏加南美地生物科技有限公司
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