Drug monitoring tool

A technology of drugs and tools, applied in the field of drug monitoring tools, can solve problems such as limiting the usefulness of information, determination, and inability to determine bleeding risks

Pending Publication Date: 2019-10-25
TAKEDA PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, with the current system, if the patient participates in an activity such as playing football at any point after the infusion event, the patient cannot determine the bleeding risk
Specifically, with current electronic diaries, patients cannot determine their factor levels at any given point in time after a prophylactic infusion event, which significantly limits the usefulness of the information provided by such sources

Method used

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Examples

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Embodiment Construction

[0034] The following is a description of example embodiments of the invention.

[0035] The present invention relates to a drug monitoring tool that enables a patient to view a personalized real-time indication of Factor VIII levels following a prophylactic infusion event. For example, drug monitoring tools include factor meters that enable users to determine real-time levels of coagulation Factor VIII. Armed with such information, patients may be better equipped, for example, to decide whether they should engage in physically demanding activities (eg, sports such as soccer). Thus, drug monitoring tools enable patients to make informed decisions about their activity levels based on accurate information about their Factor VIII levels. In addition, the factor meter provided by the drug monitoring tool enables patients to determine the time-varying factor VIII in their system at any given time after a prophylactic infusion event. Advantageously, the patient is then able to plan...

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Abstract

Embodiments of the present disclosure relate to a drug monitoring tool. The drug monitoring tool comprises a data receiver and an interactive user interface. The data receiver is configured to receivea pharmacokinetic (PK) profile of a patient. The interactive user interface is configured to display, to the patient, a time-varying therapeutic plasma protein level of the patient. The time-varyingtherapeutic plasma protein level is based on an administered dose of a clotting factor VIII and the PK profile of the patient.

Description

[0001] Related applications [0002] This application claims the benefit of U.S. Provisional Application No. 62 / 451,391, filed January 27, 2017. The entire teachings of the above applications are incorporated herein by reference. Background technique [0003] Factor VIII is a blood clotting protein that is activated in response to injury or bleeding. Individuals with relatively low levels of factor VIII are susceptible to prolonged internal or external bleeding events resulting from unexplained injury and / or spontaneous bleeding. Although skin bleeding is not serious, internal bleeding in joints, muscles, and organs can cause permanent damage, disfigurement, and even death. [0004] Patients with hemophilia A have a genetic defect that causes low levels of clotting factor VIII. The amount of factor VIII in the patient is expressed as a percentage relative to normal levels. Patients with factor VIII of 5 to 40 percent are considered to have mild hemophilia A, while those w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H20/10G16H50/30G16H50/50G06N7/00G09C5/00G06V30/224
CPCA61K38/37A61K38/48C07K14/755C12N9/64G06N7/00G16H50/30G16H50/50G09C5/00G16B40/00G16B50/00G16C20/90G16H20/10G06N7/01G16H10/60G16C20/30H04L9/0637
Inventor M·纳尔逊R·皮希勒G·施波茨
Owner TAKEDA PHARMA CO LTD
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