Standardized morus australis root extract as well as preparation method and application thereof

A technology of extract and mulberry, applied in the field of standardized extract of mulberry root and preparation thereof, can solve the problem that the chemical composition of the root and its activity are less researched, and there is no report on the application of mulberry root extract and its components. and other problems, to achieve the effect of good liver protection activity

Inactive Publication Date: 2019-12-13
NORTHWEST UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Find through literature search to prior art, for the research of chicken mulberry, concentrate on leaf and bark part more, to the chemical composit

Method used

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  • Standardized morus australis root extract as well as preparation method and application thereof
  • Standardized morus australis root extract as well as preparation method and application thereof
  • Standardized morus australis root extract as well as preparation method and application thereof

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Embodiment Construction

[0025] In order to make the objects and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the embodiments and accompanying drawings. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0026] like figure 1 Shown, the preparation method of a kind of chicken mulberry root standardized extract of the present invention comprises the following steps:

[0027] Step 1, take chicken mulberry root 8.0kg, and pulverize;

[0028] Step 2, pass the pulverized chicken mulberry root through a 100-mesh sieve, first extract twice with absolute ethanol at room temperature, each time for 24 hours, each time with 40 L of absolute ethanol, filter, and combine the two ethanol extracts to obtain chicken mulberry root -EtOH extract; the filter residue is then extracted with water and extracted twice by normal temperatur...

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Abstract

The invention discloses a standardized morus australis root extract as well as a preparation method and application thereof. The extract comprises the following active components: 12.12 mg/g of Cudraflavone B; 1.86 mg/g of Morusingin L; 14.03 mg/g of Cudraflavone C; 7.70 mg/g of Kuwanon C; 1.42 mg/g of Austraone A; 8.53 mg/g of Morusin; 12.74 mg/g of Mulberrofuran G; 43.42 mg/g Mulberrofuran F; 86.51 mg/g Moracenin B and 4.36 mg/g of Kuwanon H. The results of activity test show that the morus australis root extract and the components have liver protection activity and can be used for preparingliver protection medicines.

Description

technical field [0001] The invention relates to the technical field of plant extraction and separation, in particular to a standardized extract of chicken mulberry root and its preparation method and application. Background technique [0002] Today, with the rapid development of medical science and technology in the world, people are facing more and more diseases. It is still difficult to achieve the effect of curing many diseases that threaten human life. Under this severe situation, medical workers are committed to developing more mild and effective treatments. Treatment methods and drugs with better effects have also achieved certain results. However, the clinical application of chemically synthesized drugs can no longer meet the treatment requirements, and more urgently, the side effects they bring to the human body have also been paid more and more attention. Natural medicines have a long history of use and play an important role in the history of human diseases. They ...

Claims

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Application Information

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IPC IPC(8): C07D493/04C07D311/40C07D311/30C07D493/06A61P1/16
CPCA61P1/16C07D311/30C07D311/40C07D493/04C07D493/06
Inventor 白乃生郭森张姗姗岳文平杨闯高兵郭雅欣王天义
Owner NORTHWEST UNIV
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