A kind of hyaluronic acid oral care composition and its preparation method and application

Abstract

A hyaluronic acid oral care composition and a preparation method and application thereof, the composition is composed of the following components: hydrolyzed hyaluronic acid with a molecular weight of 2 to 5 kDa or 30% to 40% of a salt thereof, and a molecular weight of 200 to 600 kDa 35%~45% of hyaluronic acid or its salts, 20%~30% of hyaluronic acid or its salts with a molecular weight of 1300~1500 kDa. The composition of the present invention is pure hyaluronic acid or its salt, no other functional ingredients are added, and the various nursing effects of HA of different molecular weight segments on the oral cavity and oral cells are fully exploited and utilized, and it has significant oral moisturizing, resisting gingival cell inflammation, repairing Damaged oral cells and other effects can comprehensively care for oral health, providing more basis for expanding the application field of hyaluronic acid and the development of other oral care products.

Description

technical field [0001] The present invention relates to a hyaluronic acid oral care composition for oral care, and also relates to a preparation method of the composition and its application in oral care products. Background technique [0002] Hyaluronic acid (HA) is an acidic mucopolysaccharide, an unbranched macromolecular glycosaminoglycan composed of repeating units of N-acetylglucosamine and D-glucuronic acid disaccharide, which exists in animal tissue cells in the stroma and in the capsule of some bacteria. Hyaluronic acid is widely used in medicine, cosmetics, food and other fields, and its molecular weight is generally 10 5 ~10 7 Da (Dalton). In addition to the functions of water retention and lubrication and regulation of osmotic pressure, hyaluronic acid also has many physiological functions, such as anti-inflammatory, anti-infection, anti-edema, promoting tissue reconstruction and wound healing. With the deepening of research and the accumulation of clinical e...

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Problems solved by technology

First of all, the above-mentioned products in the prior art are finished products of liquid dosage forms and films, which belong to terminal products and cannot be added to other oral care products, so the application range is narrow; secondly, the above-mentioned products are mainly aimed at the problem of dry mouth. The main focus is the moisturizing effect of hyaluronic acid, and the other effects of hyaluronic acid have not been fully developed. It is still necessary to add other non-hyaluronic acid ingredients or auxiliary materials with oral care effects (such as antibacterial, repairing, etc.) to meet the requirements. Care needs for other oral problems

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