Preparation and method of an immunomodulatory peptide

Abstract

The invention provides a method for separating and purifying immunomodulatory peptides by using Radix Pseudostellariae. The method takes Radix Pseudostellariae as raw material, and obtains specific immunomodulatory peptides after protein extraction, pepsin and trypsin hydrolysis, separation and purification, and freeze-drying. The polypeptide has a molecular weight of 522 Da and its complete amino acid sequence is: Arg‑Gly‑Pro‑Pro‑Pro. The invention eliminates the defects of immunoregulatory drugs, eliminates public concerns about artificial immune modulators, and lays a theoretical foundation for the development of immune polypeptides based on food sources and the exploration of their wide application in food and medicine.

Description

technical field

[0001] The invention relates to a method for separating and purifying immunoregulatory peptides from Radix Pseudostellariae, belonging to the field of biotechnology. Background technique

[0002] Immunity is a specific physiological reaction that occurs when the body contacts "antigenic foreign bodies" or "foreign molecules", and its main purpose is to maintain the homeostasis of the body. The immune system, which is responsible for carrying out the immune function of the body, is a network of cells, tissues and organs that eliminates potentially harmful substances such as bacteria, viruses, fungi, protozoa, and prevents the growth of cancer cells. In the body's survival, the immune system acts as the first line of defense against pathogens, providing protection before bodily functions are impaired. However, the immune system is also affected by many factors, including stress, unhealthy lifestyle, pathogens and antigens, which can damage the body's immune sy...

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